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Oleuropein and related compounds

Journal of the Science of Food and Agriculture, 2000
Peer ...
Juan CARLOS Espin, Hj Wichers
exaly   +4 more sources

The biotransformation of oleuropein in rats

Biomedical Chromatography, 2013
ABSTRACTA highly sensitive and specific LC‐MS/MS method was developed to investigate the in vivo bio‐transformation of oleuropein in rat. Rat feces and urine samples collected after oral administration were determined by liquid chromatography coupled to tandem mass spectrometry with electrospray ionization in the negative‐ion mode.
Peiyan, Lin   +5 more
openaire   +2 more sources

The Antimicrobial Activities of Oleuropein and Hydroxytyrosol

2022
Several studies have reported that olive leaf extract and its constituents, particularly oleuropein and hydroxytyrosol, have health benefits including antioxidant and antimicrobial properties. Oleuropein and hydroxytyrosol have significant in vitro activity against fungi including opportunistic pathogen Candida albicans. Both compounds target virulence
Nataša Zorić, Ivan Kosalec
openaire   +1 more source

Highlights in Oleuropein Aglycone structure

Natural Product Research, 2005
Oleuropein hydrolysis products, obtained both by endogenous beta-glucosidase and almond commercial one, were investigated by classic methodologies and by 1HNMR experiments. We found that both presence and relative amount of the different compounds in the reaction mixture are stricly related to the used enzyme.
MARRA C., GUISO, Marcella
openaire   +3 more sources

Oleuropein: Molecular Dynamics and Computation

Current Medicinal Chemistry, 2017
Olive oil and table olive biophenols have been shown to significantly enrich the hedonic-sensory and nutritional quality of the Mediterranean diet. Oleuropein is one of the predominant biophenols in green olives and leaves, which not only has noteworthy freeradical quenching activity but also putatively reduces the incidence of various cancers ...
Gentile, Luigi   +2 more
openaire   +3 more sources

Antimycoplasmal Activity of Oleuropein

2010
Publisher Summary One of the most critical aspects of mycoplasmal infections is the frequent inability to control such infections with appropriate broad-spectrum antibiotics. Although the tetracyclines and erythromycin are effective chemotherapeutic agents for many mycoplasmal infections, M. fermentans and M.
P. M. Furneri   +2 more
openaire   +3 more sources

NMR Experiments of Oleuropein Biomimetic Hydrolysis

Journal of Agricultural and Food Chemistry, 1999
The oleuropein hydrolytic conversion, under biomimetic conditions, induced by the endogenous enzymatic system of the olive fruit, has been monitored by the intermediate derivative formation through (1)H and (13)C NMR spectra; the assigned molecular structures reveal the identity of new bioactive biophenolic metabolites, the hemiacetal aglycon, and the ...
A. D. BIANCO   +3 more
openaire   +3 more sources

Hemisynthetic derivatives of oleuropein

Planta Medica, 2012
Oleuropein (1), the major constituent of Olea europea leaves, has been found to possess a large range of pharmacological properties. In this context, because of the non-specificity of these effects, different analogs have been synthesized from 1 in order to study structure/activity relationships.
C Lemus   +2 more
openaire   +1 more source

Studies on the Mechanism of the Antimicrobial Action of Oleuropein*

Journal of Applied Bacteriology, 1972
S ummary : Oleuropein, the bitter principle of green olives, is surface active; this and its effect on cell membranes, as demonstrated with human erythrocytes, seems to be the basis of its antimicrobial activity.
B, Juven, Y, Henis, B, Jacoby
openaire   +2 more sources

Oleuropein Ameliorates Acute Colitis in Mice

Journal of Agricultural and Food Chemistry, 2011
Oleuropein, the major secoiridoid in olive tree leaves, possesses a wide range of health promoting properties. It has recently been shown to exhibit anti-inflammatory activity. We have evaluated the effect of oleuropein on dextran sulfate sodium (DSS)-induced experimental colitis in mice in order to provide insight into its mechanisms of action.
Elisa, Giner   +5 more
openaire   +2 more sources

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