Results 71 to 80 of about 243,434 (387)

Melatonin in the mammalian olfactory bulb [PDF]

Neuroscience, 2014
Melatonin is a neurohormone associated with circadian rhythms. A diurnal rhythm in olfactory sensitivity has been previously reported and melatonin receptor mRNAs have been observed in the olfactory bulb, but the effects of melatonin in the olfactory bulb have not been explored.
John T. Corthell, James Olcese, Paul Q. Trombley   +2 more
openaire   +4 more sources

In Situ Proliferating Peptide Nanoparticle Augments Multi‐Target Intervention of Secondary Brain Damage Following Subarachnoid Hemorrhage

Advanced Science, EarlyView.
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang, Peisen Yao, Fuxiang Chen, Shufa Zheng, Xuegang Niu, Haojie Wang, Yuanxiang Lin, Bin Gao, Dezhi Kang   +8 more
wiley   +1 more source

Olfactory bulb surroundings can help to distinguish Parkinson’s disease from non-parkinsonian olfactory dysfunction

NeuroImage: Clinical, 2020
Background: The olfactory bulb is one of the first regions of insult in Parkinson’s disease (PD), consistent with the early onset of olfactory dysfunction. Investigations of the olfactory bulb may, therefore, help early pre-motor diagnosis.
Cécilia Tremblay, Jie Mei, Johannes Frasnelli   +2 more
doaj  

Intact olfaction in a mouse model of multiple system atrophy. [PDF]

PLoS ONE, 2013
BACKGROUND: Increasing evidence suggests that olfaction is largely preserved in multiple system atrophy while most patients with Parkinson's disease are hyposmic.
Florian Krismer, Gregor K Wenning, Yuntao Li, Werner Poewe, Nadia Stefanova   +4 more
doaj   +1 more source

Tryptophan-5-HT pathway disorder was uncovered in the olfactory bulb of a depression mice model by metabolomic analysis

Frontiers in Molecular Neuroscience, 2022
Major depression (MD) is a severe mental illness that creates a heavy social burden, and the potential molecular mechanisms remain largely unknown. Lots of research demonstrate that the olfactory bulb is associated with MD.
Guanghui Chen, Siqi Zhou, Qiang Chen, Mengmeng Liu, Meixue Dong, Jiabao Hou, Benhong Zhou   +6 more
doaj   +1 more source

The Role of Astrocytes in the Generation, Migration, and Integration of New Neurons in the Adult Olfactory Bulb

Frontiers in Neuroscience, 2016
In mammals, new neurons in the adult olfactory bulb originate from a pool of neural stem cells in the subventricular zone of the lateral ventricles. Adult-born cells play an important role in odor information processing by adjusting the neuronal network ...
Archana Gengatharan, R. R. Bammann, A. Saghatelyan   +2 more
semanticscholar   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

Advanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang, Wengui Lu, Zhifei Cheng, Luyao Wang, Zhenzhen Jiang, Yike Yue, Pengyu Jiang, Zehua Xia, Lei He, Fengying Wang, Limin Wu, Qi Wang, Hui Han   +12 more
wiley   +1 more source

Cytokines and olfactory bulb microglia in response to bacterial challenge in the compromised primary olfactory pathway

Journal of Neuroinflammation, 2012
Background The primary olfactory pathway is a potential route through which microorganisms from the periphery could potentially access the central nervous system.
Herbert Rosalind P, Harris Julie, Chong Kim, Chapman Jamie, West Adrian K, Chuah Meng   +5 more
doaj   +1 more source

First Natural Endocranial Cast of a Fossil Snake (Cretaceous of Patagonia, Argentina) [PDF]

, 2017
In this study, we describe a natural endocranial cast included in a partially preserved medium‐sized skull of the Upper Cretaceous South American snake Dinilysia patagonica.
Albino, Adriana Maria, Dozo, Maria Teresa, Trivino, Laura Natalia, Williams, Jorge Daniel   +3 more
core   +2 more sources

The olfactory bulbs in Alzheimer's disease. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1984
The olfactory bulbs have been examined in patients with Alzheimer's disease and compared with those in elderly undemented and younger undemented control patients. In Alzheimer's disease neurofibrillary tangles were found in the anterior olfactory nucleus but not elsewhere in the olfactory bulb. Cell loss in the anterior olfactory nucleus was also found
Esiri, M, Wilcock, G
openaire   +4 more sources