Results 71 to 80 of about 247,698 (320)
Journal of Neuroinflammation, 2012 Background The primary olfactory pathway is a potential route through which microorganisms from the periphery could potentially access the central nervous system.
Herbert Rosalind P +5 more
doaj +1 more source
Intact olfaction in a mouse model of multiple system atrophy. [PDF]
PLoS ONE, 2013 BACKGROUND: Increasing evidence suggests that olfaction is largely preserved in multiple system atrophy while most patients with Parkinson's disease are hyposmic.
Florian Krismer +4 more
doaj +1 more source
Metal concentrations and distributions in the human olfactory bulb in Parkinson’s disease
Scientific Reports, 2017 In Parkinson’s disease (PD), the olfactory bulb is typically the first region in the body to accumulate alpha-synuclein aggregates. This pathology is linked to decreased olfactory ability, which becomes apparent before any motor symptoms occur, and may ...
Bronwen Gardner +6 more
semanticscholar +1 more source
The role of two anatomically separate olfactory bulbs in shark food odor tracking [PDF]
, 2017 Most sharks have well-developed olfactory systems and depend to a large degree on odor information to locate food, home and navigate, and possibly detect predators and mates.
Lohe, Adrienne
core +1 more source
Metastasizing esthesioneuroblastoma in a dog [PDF]
, 2014 A 7-year-old Afghan hound presented with a history of disorientation, loss of vision, and seizures. Magnetic resonance imaging helped identify a mass at the level of the main olfactory bulb that compressed and displaced adjacent tissues in the cribriform
Herden, Christiane +3 more
core +1 more source
Advanced Materials, EarlyView.This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba +20 more
wiley +1 more source
Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. [PDF]
PLoS ONE, 2017 Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfactory nerves. We have previously demonstrated that the cribriform plate is permissive for T cells and monocytes and that viruses can enter the bulb upon ...
Carolin Piotrowski +7 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2022 Major depression (MD) is a severe mental illness that creates a heavy social burden, and the potential molecular mechanisms remain largely unknown. Lots of research demonstrate that the olfactory bulb is associated with MD.
Guanghui Chen +6 more
doaj +1 more source
Corticofugal projections from the anterior olfactory nucleus target olfactory bulb principal cells [PDF]
, 2011 The anterior olfactory nucleus (AON) is a cortical structure reciprocally connected with the olfactory bulb (OB) and the piriform cortex. Here, using small extracellular and intracellular injections to trace the terminal projections in the OB from ...
Kurt R. Illig
core +2 more sources
Advanced Science, EarlyView.The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi +15 more
wiley +1 more source