Results 111 to 120 of about 115,804 (336)

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source

Biochemical and Genetic Studies of UBR3, a Ubiquitin Ligase with a Function in Olfactory and Other Sensory Systems [PDF]

, 2007
Our previous work identified E3 ubiquitin ligases, termed UBR1-UBR7, that contain the ~70-residue UBR box, a motif important for the targeting of N-end rule substrates.
Hellweg, Rainer, Hörtnagl, Heidi, Kwon, Yong Tae, Sohr, Reinhard, Tasaki, Takafumi, Varshavsky, Alexander, Xia, Zanxian   +6 more
core   +1 more source

Trajectory of olfactory cortex degeneration from normal cognition to Alzheimer's disease: Insights from multimodal neuroimaging

Neurobiology of Disease
Objective: The olfactory cortex is among the earliest brain regions affected by Alzheimer's disease (AD), with olfactory deficits frequently preceding cognitive decline.
Simin Yang, Bo Xie, Dan Liao, Yuejiao Sun, Zhuo Wang, Huimao Zhang, Yu Yang, Chunjie Guo   +7 more
doaj   +1 more source

Review of Memristors for In‐Memory Computing and Spiking Neural Networks

Advanced Intelligent Systems, EarlyView.
Memristors uniquely enable energy‐efficient, brain‐inspired computing by acting as both memory and synaptic elements. This review highlights their physical mechanisms, integration in crossbar arrays, and role in spiking neural networks. Key challenges, including variability, relaxation, and stochastic switching, are discussed, alongside emerging ...
Mostafa Shooshtari, Teresa Serrano‐Gotarredona, Bernabé Linares‐Barranco   +2 more
wiley   +1 more source

Plasticity of olfactory bulb inputs mediated by dendritic NMDA-spikes in piriform cortex [PDF]

, 2021
Amit Kumar, Edi Barkai, Jackie Schiller
openalex   +1 more source

Modulation of auditory responses by modality-specific attention in rat primary auditory cortex [PDF]

, 2008
How does attention modulate sensory representations? In order to probe the underlying neural mechanisms, we established a simple rodent model of modality-specific attention.
Anthony M. Zador, Lung-Hao Tai
core   +2 more sources

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Sensory Measurements: Coordination and Standardization [PDF]

, 2015
Do sensory measurements deserve the label of “measurement”? We argue that they do. They fit with an epistemological view of measurement held in current philosophy of science, and they face the same kinds of epistemological challenges as physical ...
A Ferguson, A Keller, A Majid, A Sorowska, A-S Barwich, Ann-Sophie Barwich, BAAS, C Bushdid, C Darwin, C Sell, CH Hawkes, DA Baylor, DA Deems, DD Stettler, DT Jones, E Barkai, E Tal, E Wnuk, EAM Gamble, FF Chen, GM Shepherd, GM Shepherd, H Chang, H Chang, Hasok Chang, I Tourbier, IJ Deary, J Canales, J Lötsch, J Michell, JH Cho, JY Lettvin, KC Elliott, LB Buck, M Jones-Gotman, M Meister, M Spehr, NE Bowman, PB Sklar, PM Wise, R Axel, RA Frank, RC Gerkin, RL Doty, RL Doty, S Firestein, S Firestein, S Hecht, S Pinker, SA Klein, SS Stevens, SS Stevens, T Hummel, T Hummel, U Pace, W Bechtel, Y Oka   +56 more
core   +1 more source

Circuit dynamics of the olfactory pathway during olfactory learning

Frontiers in Neural Circuits
The olfactory system plays crucial roles in perceiving and interacting with their surroundings. Previous studies have deciphered basic odor perceptions, but how information processing in the olfactory system is associated with learning and memory is ...
Yutian J. Zhang, Jason Y. Lee, Kei M. Igarashi, Kei M. Igarashi, Kei M. Igarashi, Kei M. Igarashi, Kei M. Igarashi   +6 more
doaj   +1 more source

Trace Amine-Associated Receptor 5 Provides Olfactory Input Into Limbic Brain Areas and Modulates Emotional Behaviors and Serotonin Transmission

Frontiers in Molecular Neuroscience, 2020
Trace amine-associated receptors (TAARs) are a class of G-protein-coupled receptors found in mammals. While TAAR1 is expressed in several brain regions, all the other TAARs have been described mainly in the olfactory epithelium and the glomerular layer ...
Stefano Espinoza, Ilya Sukhanov, Evgeniya V. Efimova, Alena Kozlova, Kristina A. Antonova, Placido Illiano, Damiana Leo, Natalia Merkulyeva, Natalia Merkulyeva, Daria Kalinina, Daria Kalinina, Pavel Musienko, Pavel Musienko, Anna Rocchi, Anna Rocchi, Liudmila Mus, Liudmila Mus, Tatiana D. Sotnikova, Raul R. Gainetdinov, Raul R. Gainetdinov   +19 more
doaj   +1 more source