Results 191 to 200 of about 670,781 (328)

Perturbed synaptic adhesion molecules signaling in neurodevelopmental disorders: The impact of metal neurotoxicity

Ibrain, EarlyView.
Synaptic adhesion molecules (SAM) are essential for the formation, maturation, function, plasticity, and assembly of synaptic connections, all critical for normal neurodevelopment. Excessive exposure to neurotoxic metals during development could disrupt the developing brain and potentially lead to neurodevelopmental disorders (NDDs).
Toheeb O. Oyerinde, Victor E. Anadu, Tobiloba S. Olajide, Ileje I. Ukwubile, Olayemi K. Ijomone, Kingsley A. Iteire, Michael Aschner, Omamuyovwi M. Ijomone   +7 more
wiley   +1 more source

A comprehensive benchmarking for spatially resolved transcriptomics clustering methods across variable technologies, organs, and replicates

iMeta, EarlyView.
Spatial clustering is a critical step in spatially resolved transcriptomics. Here, we conducted a comprehensive benchmarking analysis of 14 spatial clustering methods using ~600 datasets, including both real‐world and simulated data spanning ten technologies and eight organs.
Renjie Chen, Yue Yao, Jingyang Qian, Xin Peng, Xin Shao, Xiaohui Fan   +5 more
wiley   +1 more source

Assessment of Small Vessel Density Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalophy (CADASIL) by High‐Resolution Black‐Blood MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Direct assessments of cerebral small vessels in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) remain a challenge. Purpose To investigate changes of cerebral small vessels in CADASIL using iso‐0.5 mm black‐blood MRI. Study Type Case control study.
Zidong Yang, Fanhua Guo, Steve Mendoza, Ziyang Huang, Yingying Li, Yunqing Ying, Xin Cheng, Qi Yang, Yonggang Shi, Danny J. J. Wang   +9 more
wiley   +1 more source

A Major Role for Intracortical Circuits in the Strength and Tuning of Odor-Evoked Excitation in Olfactory Cortex [PDF]

, 2011
Cindy Poo, Jeffry S. Isaacson
openalex   +1 more source

The Sense of Smell (SoS) Atlas: Its Creation and First Application to Investigate COVID‐19 Related Anosmia With a Comprehensive Quantitative MRI Protocol

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The loss of smell (anosmia) has been noted in numerous diseases, including COVID‐19. Inflammatory and microstructural alterations are possible underlying mechanisms of anosmia in COVID‐19. However, no atlas exists to study olfaction and the associated tissue property changes.
Marta Gaviraghi, Eleonora Lupi, Elena Grosso, Andrea Fusari, Mattia Baiguera, Anita Monteverdi, Marco Battiston, Francesco Grussu, Baris Kanber, Ferran Prados Carrasco, Rebecca S. Samson, Janine Makaronidis, Marios C. Yiannakas, Michael S. Zandi, Rachel L. Batterham, Egidio D'Angelo, Fulvia Palesi, Claudia A. M. Gandini Wheeler‐Kingshott   +17 more
wiley   +1 more source

Alterations in Olfactory Cortex Volume in Mild Cognitive Impairment and Mild Alzheimer's Disease Dementia: A Study of Sex-Related Differences. [PDF]

Brain Sci
Alotaibi MM, De Marco M, Graham R, Venneri A.   +3 more
europepmc   +1 more source

NMDA antagonists increase recovery of evoked potentials from slices of rat olfactory cortex after anoxia [PDF]

, 1994
Maged M. Yassin, C. Norman Scholfield
openalex   +1 more source

Balanced feedforward inhibition and dominant recurrent inhibition in olfactory cortex

Proceedings of the National Academy of Sciences of the United States of America, 2016
Adam M. Large, N. Vogler, S. Mielo, A. Oswald   +3 more
semanticscholar   +1 more source

Basal Forebrain Volume Predicts Disease Conversion in Prodromal Synucleinopathy

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal stage of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The basal forebrain (BF), a key cholinergic structure, is a site of known pathology in later stages of Lewy body disorders.
Lachlan Churchill, Ajay Konuri, Anna Ignatavicius, Jack Anderson, Simon J.G. Lewis, Elie Matar   +5 more
wiley   +1 more source

The Wire Is Not the Territory: Understanding Representational Drift in Olfaction With Dynamical Systems Theory

Topics in Cognitive Science, EarlyView., 2023
Abstract Representational drift is a phenomenon of increasing interest in the cognitive and neural sciences. While investigations are ongoing for other sensory cortices, recent research has demonstrated the pervasiveness in which it occurs in the piriform cortex for olfaction.
Ann‐Sophie Barwich, Gabriel J. Severino   +1 more
wiley   +1 more source