Results 151 to 160 of about 50,072 (244)

Prodromal Lewy Body Symptoms and α-Synuclein Seeding in Idiopathic Olfactory Dysfunction. [PDF]

open access: yesMov Disord Clin Pract
McWilliam OH   +15 more
europepmc   +1 more source

Characterization of postnatal brain injury and behavioural deficits in a rat model of placental insufficiency‐induced fetal growth restriction

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Fetal growth restriction (FGR) is a common pregnancy complication associated with long‐term neurodevelopmental impairments. Using the reduced uterine perfusion pressure (RUPP) rat model of placental insufficiency‐induced FGR, this study demonstrates that FGR leads to persistent anatomical, histological and behavioural ...
Judit Alhama‐Riba   +8 more
wiley   +1 more source

miR‐146a/b‐5p‐IRAK1‐NF‐κB Axis Regulates Unexplained Recurrent Spontaneous Abortion

open access: yesJournal of Molecular Recognition, Volume 39, Issue 3, May 2026.
ABSTRACT Unexplained recurrent spontaneous abortion (URSA) remains a prevalent obstetric issue, the underlying causes of which are still not fully understood. MicroRNAs (miRNAs) have the potential to influence URSA through their regulation of gene expression.
Fengping He   +7 more
wiley   +1 more source

Early‐life Giardia infection and behavioural dysregulation in two dogs: A case‐based exploration of the gut microbiome–brain axis

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This case report describes two dogs exhibiting severe behavioural problems, both diagnosed with early‐life giardiasis and raised in environments lacking adequate maternal care and socialisation. Both dogs experienced chronic gastrointestinal and dermatological issues, as well as prolonged early‐life stress, which likely contributed to ...
Daniëlle Hartman   +3 more
wiley   +1 more source

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

open access: yesClinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu   +10 more
wiley   +1 more source

VGLUT1 and PSD‐95 Expression Remains Stable in the Prefrontal and Cerebellar Cortices of the VPA Autism Rat Model

open access: yesDevelopmental Neurobiology, Volume 86, Issue 2, April 2026.
ABSTRACT Autism spectrum disorder (ASD) has recently been described as a synaptopathy where dysregulation at the level of the synapse is thought to evoke an excitation–inhibition (E/I) imbalance implicated in its pathogenesis. The mechanisms through which alterations in glutamatergic signaling bring about an E/I imbalance remain elusive.
Megan Reveley   +4 more
wiley   +1 more source

Editorial: Olfactory dysfunction in neurodegenerative diseases. [PDF]

open access: yesFront Neurosci
Dasgupta D, Heinbockel T, Ghatak S.
europepmc   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi   +5 more
wiley   +1 more source

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