Results 131 to 140 of about 69,587 (287)

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

The effect of polyamines on the expression of olfactory related genes in the diamondback moth, Plutella xylostella (Lepidoptera: Yponomeutidae)

European Journal of Entomology, 2015
Polyamines are nitrogenous compounds that alter the odour sensitivity of insects. The objective of this study was to determine the effects of polyamines on the expression levels of olfactory-related genes in male/female adult diamondback moths, Plutella ...
Zhichun ZHANG, Manqun WANG, Guanghua LUO, Gufeng ZHANG, Jichao FANG   +4 more
doaj   +1 more source

Evolution of a complex locus : exon gain, loss and divergence at the Gr39a locus in Drosophila [PDF]

, 2008
Background. Gene families typically evolve by gene duplication followed by the adoption of new or altered gene functions. A different way to evolve new but related functions is alternative splicing of existing exons of a complex gene.
Butlin, Roger K., Gardiner, Anastasia, Gardiner, A., Jordan, W.C., Ritchie Michael G., Ritchie, M.G., Jordan, William C., Michael G Ritchie, Barker, Daniel, William C Jordan, Barker, D., Ritchie, Michael G., Gardiner Anastasia, Daniel Barker, Anastasia Gardiner, Barker Daniel, Roger K Butlin, Jordan William C., Butlin, R.K., Butlin Roger K.   +19 more
core   +1 more source

SpaMode: A Broadly Applicable Framework for Deciphering Spatial Multi‐Omics Using Multimodal Mixture of Disentangled Experts

Advanced Science, EarlyView.
SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng, Xinlei Huang, Xiang Zhou, Dian Meng, Ziyue Qiao, Zhiyuan Yuan, Lixin Cheng   +6 more
wiley   +1 more source

Summary of olfactory genes and sex pheromone types in Lepidoptera. [PDF]

, 2016
Summary of olfactory genes and sex pheromone types in Lepidoptera.
Ya-Nan Zhang (192704), Tian-Tian Wang (68319), Long-Wa Zhang (734574), Shi-Chang Jiang (3220995), Jing Zhang (23775), Yun-Qiu Yang (3220998), Ke Kang (734573), Long Sun (572625), Chang-Chun Huang (3221007), Li-Ya Jiang (3221001), De-Gui Ding (3221004)   +10 more
core   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Real‐Time and Non‐Invasive Detection of Respiratory Viral Infections Using an Intelligent Odor Monitoring System (IOMS)

Advanced Science, EarlyView.
An intelligent odor monitoring system integrates an IVC animal model, gas sensor array, real‐time resistance readout, and machine‐learning analysis to continuously monitor infection‐associated odor changes. The platform captures longitudinal sensor responses, distinguishes infected from healthy states, and supports early‐stage respiratory viral ...
Yajie Shen, Weifeng Yuan, Long Li, Yucheng Zheng, Kenan Liu, Hegeng Li, Hua‐Yao Li, Yongliang Zhao, Binzhou Ying, Lanpeng Guo, Wenjian Zhang, Shu‐Ming Kuo, Zirui Zhang, Yufan Deng, Bohan Yin, Zhaocheng Luo, Ke Xu, Huan Liu   +17 more
wiley   +1 more source

Genomics of Mature and Immature Olfactory Sensory Neuron [PDF]

, 2016
The Excel file contains probabilistic predictions of which genes are expressed in mature versus immature olfactory sensory neurons, versus the sum of all other cell types in the olfactory epithelium.
McClintock, Timothy S.
core   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

YY1's DNA-Binding motifs in mammalian olfactory receptor genes [PDF]

, 2009
Background YY1 is an epigenetic regulator for a large number of mammalian genes. While performing genome-wide YY1 binding motif searches, we discovered that the olfactory receptor (OLFR) genes have an unusual cluster of YY1 binding sites within their ...
Faulk Christopher D, Faulk, Christopher D., Kim, Joomyeong, Kim Joomyeong   +3 more
core   +1 more source