Results 91 to 100 of about 259,025 (282)

Immunolocalization of arthropsin in the onychophoran Euperipatoides rowelli (Peripatopsidae)

open access: yesFrontiers in Neuroanatomy, 2016
Opsins are light-sensitive proteins that play a key role in animal vision and are related to the ancient photoreceptive molecule rhodopsin found in unicellular organisms. In general, opsins involved in vision comprise two major groups: the rhabdomeric (r-
Isabell Schumann   +3 more
doaj   +1 more source

Underlying Mathematics in Diversification of Human Olfactory Receptors in Different Loci [PDF]

open access: yes, 2010
As per conservative estimate, approximately (51-105) Olfactory Receptors (ORs) loci are present in human genome occurring in clusters. These clusters are apparently unevenly spread as mosaics over 21 pair of human chromosomes.
Arunava Goswami   +2 more
core   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

open access: yesAdvanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi   +15 more
wiley   +1 more source

Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway

open access: yesFrontiers in Cellular Neuroscience, 2018
One key signaling pathway known to influence neuronal migration involves the extracellular matrix protein Reelin. Typically, signaling of Reelin occurs via apolipoprotein E receptor 2 (ApoER2) and very low-density lipoprotein receptor (VLDLR), and the ...
Leigh Dairaghi   +11 more
doaj   +1 more source

Pregnancy Changes the Response of the Vomeronasal and Olfactory Systems to Pups in Mice [PDF]

open access: gold, 2020
Cinta Navarro-Moreno   +7 more
openalex   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

open access: yesAdvanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie   +5 more
wiley   +1 more source

Projection neurons are necessary for the maintenance of the mouse olfactory circuit

open access: yeseLife
The assembly and maintenance of neural circuits is crucial for proper brain function. Although the assembly of brain circuits has been extensively studied, much less is understood about the mechanisms controlling their maintenance as animals mature.
Luis Sánchez-Guardado   +4 more
doaj   +1 more source

Histological markers in nasal mucosa of patients with Alzheimer's disease [PDF]

open access: yes, 1998
Neuropathological changes such as dystrophic neurites and the presence of abnormal tau protein in the olfactory system, including primary sensory cells and nerve fibres have previously been demonstrated in nasal mucosa tissue of patients with Alzheimer's
Golombowski, Sidonie   +7 more
core   +1 more source

Cortico‐Striatal‐Midbrain Circuit Dysregulation Underlying MK‐801 Induced Impulsivity and the Ameliorative Effects of SEP

open access: yesAdvanced Science, EarlyView.
Impulsivity is a symptom across multiple psychiatric disorders, yet its neural basis remains elusive. This study shows that the NMDAR antagonist MK‐801 elevates dopamine release and disrupts neuronal selectivity in the nucleus accumbens, leading to impulsive behavior.
Xueru Wang   +6 more
wiley   +1 more source

Neuroethology of olfactory-guided behavior and its potential application in the control of harmful insects [PDF]

open access: yes, 2016
Harmful insects include pests of crops and storage goods, and vectors of human and animal diseases. Throughout their history, humans have been fighting them using diverse methods.
Guerenstein, Pablo Gustavo   +2 more
core   +2 more sources

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