Results 61 to 70 of about 5,107 (150)

The Sense of Smell (SoS) Atlas: Its Creation and First Application to Investigate COVID‐19 Related Anosmia With a Comprehensive Quantitative MRI Protocol

Journal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 574-593, February 2026.
ABSTRACT Background The loss of smell (anosmia) has been noted in numerous diseases, including COVID‐19. Inflammatory and microstructural alterations are possible underlying mechanisms of anosmia in COVID‐19. However, no atlas exists to study olfaction and the associated tissue property changes.
Marta Gaviraghi, Eleonora Lupi, Elena Grosso, Andrea Fusari, Mattia Baiguera, Anita Monteverdi, Marco Battiston, Francesco Grussu, Baris Kanber, Ferran Prados Carrasco, Rebecca S. Samson, Janine Makaronidis, Marios C. Yiannakas, Michael S. Zandi, Rachel L. Batterham, Egidio D'Angelo, Fulvia Palesi, Claudia A. M. Gandini Wheeler‐Kingshott   +17 more
wiley   +1 more source

Selection for Function in Complex Distributed Pathological Systems

Evolutionary Applications, Volume 19, Issue 2, February 2026.
ABSTRACT Pathological processes are often conceptualized as localized phenomena anchored in a primary tumor, a focal lesion, or a single organ. However, growing evidence indicates that many diseases persist and progress as complex distributed systems, maintained by interactions among multiple sites.
Frédéric Thomas, Antoine M. Dujon, Daniel Vaiman, Gerard Eberl, Catherine Alix‐Panabières, Pascal Pujol, Beata Ujvari, Jordan Meliani, Aurora M. Nedelcu, Jean‐Pascal Capp   +9 more
wiley   +1 more source

Characterization of aromatase expression in the adult male and female mouse brain. I. Coexistence with oestrogen receptors α and β, and androgen receptors. [PDF]

PLoS ONE, 2014
Aromatase catalyses the last step of oestrogen synthesis. There is growing evidence that local oestrogens influence many brain regions to modulate brain development and behaviour.
Davor Stanić, Sydney Dubois, Hui Kheng Chua, Bruce Tonge, Nicole Rinehart, Malcolm K Horne, Wah Chin Boon   +6 more
doaj   +1 more source

Cervical Intranodal Schwannoma and Its Malignant Transformation: A Case Report With Literature Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case report highlights a rare malignant transformation of a cervical intranodal schwannoma in a 46‐year‐old man. The patient first came in with a slow‐growing, painless nodule in the right neck. Surgical excision was performed and histopathological examinations revealed a benign intranodal cellular schwannoma.
Shahab Hussain, Zia Ullah Khan, Nazneen Liaqat, Syed Wajihullah Shah, Kainat Khan, Jibran Ikram   +5 more
wiley   +1 more source

Herpes Simplex Virus Infection With Multiple Cerebral Hemorrhages: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Herpes simplex virus (HSV) infection may trigger rare vascular complications that lead to multiple cerebral hemorrhages. This case emphasizes considering HSV in unexplained cerebral hemorrhage among immunocompromised individuals with systemic symptoms, as timely antiviral treatment effectively improves clinical outcomes.
Zhongzhan Wu, Fangfang Liu, Fugui Wang, Jie Li, Houqing Lu   +4 more
wiley   +1 more source

Oxytocinergic Signaling in Zebrafish: Translational Perspectives for Autism Spectrum Disorder

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Alterations in oxytocin signaling are strongly implicated in the social and cognitive deficits characterizing Autism Spectrum Disorder (ASD) and other neurodevelopmental conditions. However, the precise mechanisms remain unclear. The zebrafish (Danio rerio) has emerged as a powerful translational model due to its evolutionarily conserved oxytocin ...
Géssica Peres, Melissa Talita Wiprich, Darlan Gusso, Carla Denise Bonan   +3 more
wiley   +1 more source

Hyperactive mTORC1 in striatum dysregulates dopamine receptor expression and odor preference behavior

Frontiers in Neuroscience
Mechanistic target of rapamycin (mTOR) plays an important role in brain development and synaptic plasticity. Dysregulation of the mTOR pathway is observed in various human central nervous system diseases, including tuberous sclerosis complex, autism ...
Lin Chen, Lin Chen, Ryo Saito, Shoko Noda-Narita, Hidetoshi Kassai, Hidetoshi Kassai, Atsu Aiba, Atsu Aiba   +7 more
doaj   +1 more source

Nanoparticles Decorated Nanotubes: Advanced Local Therapies From Anodized Nanoengineered Titanium Implants

Advanced Functional Materials, Volume 35, Issue 50, December 9, 2025.
This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra, Liwen Zhang, Tianqi Guo, Sašo Ivanovski, Ruirui Qiao, Karan Gulati   +5 more
wiley   +1 more source

Differential potentiation of odor aversion and yawning by melanocortin 4 receptor signaling in distinct regions of the ventral striatum

Frontiers in Neuroscience
Although animal behavior is influenced by neuromodulatory signals, the underlying mechanism remains elusive. The ventral striatum, which consists of the olfactory tubercle (OT) and nucleus accumbens (NAc), promotes motivated behaviors and receives ...
Md Tasnim Alam, Md Monjurul Ahasan, Shogo Shimizu, Yoshihiro Murata, Mutsuo Taniguchi, Masahiro Yamaguchi   +5 more
doaj   +1 more source

CD73 is a major regulator of adenosinergic signalling in mouse brain.

PLoS ONE, 2013
CD73 (ecto-5'-nucleotidase) is a cell surface enzyme that regulates purinergic signalling by desphosphorylating extracellular AMP to adenosine. 5'-nucleotidases are known to be expressed in brain, but the expression of CD73 and its putative physiological
Natalia Kulesskaya, Vootele Võikar, Marjaana Peltola, Gennady G Yegutkin, Marko Salmi, Sirpa Jalkanen, Heikki Rauvala   +6 more
doaj   +1 more source