Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong+4 more
wiley +1 more source
Pro-Inflammatory Molecules Implicated in Multiple Sclerosis Divert the Development of Human Oligodendrocyte Lineage Cells. [PDF]
Blaszczyk GJ+8 more
europepmc +1 more source
A Chemogenetic Toolkit for Inducible, Cell Type‐Specific Actin Disassembly
ChiActs are novel actin‐perturbing genetic tools that can be rapidly activated by chemical actuators and optogenetically targeted to distinct subcellular locations using light. ChiActs rapidly induce actin disassembly in several model cell types and are able to perturb actin‐dependent nano‐assembly and cellular functions, including inhibition of ...
Tien‐Hung Lan+5 more
wiley +1 more source
AMX0035 Mitigates Oligodendrocyte Apoptosis and Ameliorates Demyelination in MCAO Rats by Inhibiting Endoplasmic Reticulum Stress and Mitochondrial Dysfunction. [PDF]
Zhang L+5 more
europepmc +1 more source
Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman+33 more
wiley +1 more source
Editorial: Non-neuronal cells in neurodegenerative diseases and psychiatric disorders. [PDF]
Estudillo E+3 more
europepmc +1 more source
TPO1, a Member of a Novel Protein Family, Is Developmentally Regulated in Cultured Oligodendrocytes [PDF]
Winfried Krueger+6 more
openalex +1 more source
General Anesthetic Exposure in the Management of Pediatric Subglottic Stenosis
ABSTRACT Objectives This study describes time spent under general anesthesia (GA) and number of procedures in children with subglottic stenosis (SGS) treated with endoscopic balloon dilation (EBD), laryngotracheal reconstruction (LTR), or both. Methods Children treated for SGS surgically between November 2014 through August 2020 were included. Patients
Kevin Koss+4 more
wiley +1 more source
Macular microvascular and structural changes on optical coherence tomography angiography in atypical optic neuritis. [PDF]
Mahatme C+4 more
europepmc +1 more source