Results 261 to 270 of about 97,181 (355)

General Anesthetic Exposure in the Management of Pediatric Subglottic Stenosis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives This study describes time spent under general anesthesia (GA) and number of procedures in children with subglottic stenosis (SGS) treated with endoscopic balloon dilation (EBD), laryngotracheal reconstruction (LTR), or both. Methods Children treated for SGS surgically between November 2014 through August 2020 were included. Patients
Kevin Koss   +4 more
wiley   +1 more source

Analysis of Oligodendrocyte Lineage Cell Progression with Cre-Mediated RiboTag Reporter Lines. [PDF]

open access: yesASN Neuro
Melchor GS   +7 more
europepmc   +1 more source

Anti‐Human Endogenous Retrovirus and Anti‐Myelin Oligodendrocyte Glycoprotein Humoral Response in Cerebrospinal Fluid of Multiple Sclerosis Patients: A Case Control Study

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT It is believed that human endogenous retrovirus (HERV)‐W plays a fundamental role in multiple sclerosis (MS) pathogenesis, probably by inducing humoral and cellular immunopathological response. HERVs present regions of similarity to myelin oligodendrocyte glycoprotein (MOG) and therefore could induce autoimmunity through the mechanism of ...
Karin C. Garcia   +11 more
wiley   +1 more source

Patient‐Derived Cortical Organoids Reveal Senescence of Neural Progenitor Cells in Hutchinson‐Gilford Progeria Syndrome

open access: yesAging Cell, EarlyView.
HGPS patient‐derived cortical organoids exhibit progerin accumulation, nuclear abnormalities, and increased senescence in rosette structures, leading to impaired neuronal differentiation and altered gene expression. ABSTRACT Hutchinson‐Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by premature aging and primarily caused by ...
Seeun Jeon   +6 more
wiley   +1 more source

Age‐Related Complement C3 Drives Memory Impairments and Associated Neuropathologies in a Mouse Model

open access: yesAging Cell, EarlyView.
Age‐related complement C3 elevation induces memory impairments and neuropathology by dysregulating astrocytic insulin signaling and triggering mitochondrial dysfunction. Critically, antibody blockade of C3 in mouse brain tissue effectively reversed learning and memory deficits in mice, demonstrating that targeting C3 is a promising therapeutic strategy.
Miaomiao Du   +10 more
wiley   +1 more source

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