Results 131 to 140 of about 81,187 (302)
Role of SoxE transcription factors in development and disease
Developmental Dynamics, EarlyView.Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley +1 more source
Identification of oligodendrocytes.
, 2013 (A-F) Low (A-C) and high (D-F) magnification images showing cells from P15 CD-1 mice expressing Olig2 and CNPase, identified as oligodendrocytes after 7 days in culture.
Ana Bribián (171285) +3 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng +11 more
wiley +1 more source
WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy
Epilepsia, EarlyView.Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara +7 more
wiley +1 more source
NADPH-diaphorase histochemistry reveals oligodendrocytes in the rainbow trout (teleosts).
, 1996 We studied the distribution of NADPH-diaphorase (NADPHd) in the brain of the rainbow trout. Not only neurons but also tanycytes and oligodendrocytes showed NADPHd positivity.
Rodriguez, M A +4 more
core +1 more source
The Pathobiology of the Oligodendrocyte [PDF]
Journal of Neuropathology and Experimental Neurology, 1997 openaire +2 more sources
A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis
Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo +7 more
wiley +1 more source
Oligodendrocytes damage in Alzheimer's disease: Beta amyloid toxicity and inflammation
Biological Research, 2005 Research on Alzheimer's disease (AD) focuses mainly on neuronal death and synaptic impairment induced by β-Amyloid peptide (Aβ), events at least partially mediated by astrocyte and microglia activation.
ALEJANDRO D ROTH +3 more
doaj
HIV-1 Infection of Cultured Human Adult Oligodendrocytes
, 1996 The mechanism through which HIV-1 causes HIV dementia (HIVD) is not well understood. Myelin pallor is a common pathological finding in HIVD and could be explained by a direct infection of oligodendrocytes or interaction with HIV-1 gp 120. To determine if
ALBRIGHT, ANDREW V. +5 more
core +1 more source
iNew Medicine, EarlyView.ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu +2 more
wiley +1 more source