Results 121 to 130 of about 81,187 (302)

Myelin biogenesis: tranport of proteolipids in oligodendrocytes. [PDF]

, 1998
The objective of the study described in this thesis was to obtain insight into cell-biological processes that are operative in the biogenesis and maintenance of myelin. In particular, the characteristics and mechanisms of protein and lipid trafficking in
Haar, Marjan Ellen van der, Haar, Marjan Ellen van der,   +1 more
core  

Can oligodendrocytes attached to myelin proliferate?

, 1988
The uptake of thymidine by oligodendrocytes in the brains of adult mice was examined after the induction of cortical traumatic lesions in an attempt to determine whether mature oligodendrocytes actively attached to myelin sheaths were capable of ...
DA Bakker, SK Ludwin
core   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

The neurovirulent GDVII strain of Theiler's virus can replicate in glial cells

, 1995
The distribution, spread, neuropathology, tropism, and persistence of the neurovirulent GDVII strain of Theiler's virus in the central nervous system (CNS) was investigated in mice susceptible and resistant to chronic demyelinating infection with TO ...
Dyson, H, Fazakerley, J K, Simas, J P
core  

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Zebrafish optic nerve regeneration involves resident and retinal oligodendrocytes

Neural Regeneration Research
The visual system of teleost fish grows continuously, which is a useful model for studying regeneration of the central nervous system. Glial cells are key for this process, but their contribution is still not well defined. We followed oligodendrocytes in
Cristina Pérez-Montes, Rosalía Hernández-García, Jhoana Paola Jiménez-Cubides, Laura DeOliveira-Mello, Almudena Velasco, Rosario Arévalo, Marina García-Macia, Adrián Santos-Ledo   +7 more
doaj   +1 more source

A role of oligodendrocytes in information processing

, 2020
Myelinating oligodendrocytes enable fast propagation of action potentials along the ensheathed axons. In addition, oligodendrocytes play diverse non-canonical roles including axonal metabolic support and activity-dependent myelination.
de Hoz, L., Tzvetanova, I., Battefeld, Arne, Meschkat, M., Kusch, K., de Hoz, Livia, Trevisiol, Andrea, Kole, M., Möbius, Wiebke, Ruhwedel, Torben, Trevisiol, A., Nave, Klaus-Armin, Kole, Maarten H. P., Kusch, Kathrin, Nave, K., Strenzke, N., Meschkat, Martin, Ruhwedel, T., Möbius, W., Battefeld, A., Moore, Sharlen, Strenzke, Nicola, Moore, S., Tzvetanova, Iva D.   +23 more
core   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

NADPH oxidase induction in oligodendrocytes increases cytotoxicity.

, 2013
(A) Injured astrocytes stimulate NADPH oxidase activity in oligodendrocytes. NADPH oxidase activity was measured in cultures treated with either oligodendrocyte media alone (OM) or injured astrocyte media (IAM) for 3 hrs.
Joshua T. Johnstone (486882), Andrea L. Johnstone (486885), John R. Bethea (152001), Paul D. Morton (486883), Damien D. Pearse (486888), Han Gao (486886), Valerie Bracchi-Ricard (486887), Arumugam R. Jayakumar (486884), Michael D. Norenberg (486889)   +8 more
core   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source