Results 251 to 260 of about 113,519 (282)

Mislocalisation of TDP-43 to the cytoplasm of either neurons or oligodendrocytes causes axonopathy and dysmyelination

Keatinge M, Juhasz SC, Shaw-McGrath T, Albayrak J, Soong D, Marshall-Phelps K, Story D, Hoodless L, Cooper J, Almeida RG, Czopka T, Hardingham G, Lyons DA, Chandran S.   +13 more
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Oligodendrocytic Gliomatosis Cerebri

Acta Neurochirurgica, 2000
We describe a very unusual case of gliomatosis cerebri (GC) with oligodendrocytic differentiation. A 65-year-old man presented with a convulsive seizure. Magnetic resonance (MR) documented diffuse enlargement of cerebral hemispheres, brainstem, and right cerebellar hemisphere.
Tancredi, A, Mangiola, A, Guiducci, A, Peciarolo, A, Ottaviano, P   +4 more
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Oligodendrocyte differentiation

2016
In the nervous system, axons transmit information in the form of electrical impulses over long distances. The speed of impulse conduction is enhanced by myelin, a lipid-rich membrane that wraps around axons. Myelin also is required for the long-term health of axons by providing metabolic support.
E S, Mathews, B, Appel
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Oligodendrocyte origins

Trends in Neurosciences, 1996
In the adult vertebrate CNS, oligodendrocytes are ubiquitously distributed throughout white matter. By contrast, in the embryonic CNS, recent studies suggest that oligodendrocyte precursors arise in a discrete ventral location. Thus, local ventral environmental signals that contribute to the overall patterning of the CNS are likely to influence the ...
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Oligodendrocytes and Myelin

Neurologic Clinics, 1995
Although it was initially thought to be a passive structure, the oligodendrocyte and myelin unit is now considered highly dynamic with many important functions beyond its role in myelination. Inhibitors of neurite growth can be localized to oligodendrocyte and myelin, highlighting the importance of oligodendrocytes in general CNS maintenance and in ...
J A, McLaurin, V W, Yong
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Oligodendrocytes and Alzheimer's disease

International Journal of Neuroscience, 2015
Extensive evidence has indicated that the breakdown of myelin is associated with Alzheimer's disease (AD) since the vulnerability of oligodendrocytes under Alzheimer's pathology easily induces the myelin breakdown and the loss of the myelin sheath which might be the initiating step in the changes of the earliest stage of AD prior to appearance of ...
Zhiyou, Cai, Ming, Xiao
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Regulation of oligodendrocyte development

Molecular Neurobiology, 1998
Oligodendrocytes are the cells responsible for the formation of myelin in the central nervous system. Recent studies demonstrated that cells of the oligodendrocyte lineage initially arise in distinct regions of the ventricular zone during early development.
D M, Orentas, R H, Miller
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The oligodendrocytic junctional complex

Cell and Tissue Research, 1978
The junctional complex of oligodendrocytes was studied by means of different electron microscopical techniques. This complex is composed of the following junctional membrane formations: 1) tight junctional domains in the oligodendrocytic membrane near the some of the cells, 2) fasciae occludentes or focal tight junctions on the outer oligodendrocytic ...
R, Dermietzel, D, Schünke, A, Leibstein
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Regulation of oligodendrocyte development

Microscopy Research and Technique, 2001
AbstractOligodendrocytes are myelinating cells in the central nervous system. Recent studies demonstrated that oligodendrocyte progenitor cells are generated from a restricted region in the ventricular zone. In the rodent spinal cord, progenitor cells appear from narrow and bilateral longitudinal columns in the ventral ventricular zone, and then ...
T, Kagawa, T, Wada, K, Ikenaka
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