Correction to: Inflammation's impact on the interaction between oligodendrocytes and axons. [PDF]
europepmc +1 more source
Brain-wide mapping of oligodendrocyte organization, oligodendrogenesis, and myelin injury. [PDF]
Xu YKT +10 more
europepmc +1 more source
STAIR‐UTE, STAIR‐STE, and MT‐derived myelin biomarkers (MPF, MWF, MMF, MTR) strongly correlate in WM, gray matter, and MS lesions. All distinguish normal from abnormal tissue, though subtle differences suggest complementary information. Histological validation is needed to confirm specificity.
James Lo +7 more
wiley +1 more source
The Flavonoid Apigenin Modulates Oligodendroglial Plasticity and Has a Neuroprotective Effect in Cerebellar Slice Cultures with Oxygen Glucose Deprivation. [PDF]
Carreira RB +7 more
europepmc +1 more source
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong +8 more
wiley +1 more source
DNAJC6 Parkinson's disease: Endolysosomal dysfunction and emerging roles for oligodendrocytes. [PDF]
Allen AG +3 more
europepmc +1 more source
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato +15 more
wiley +1 more source
Impaired myelination in multiple sclerosis organoids: p21 links oligodendrocyte dysfunction to disease subtype. [PDF]
Sadiq SA +4 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Human Myelin Spheres for in Vitro Oligodendrocyte Maturation, Myelination and Neurological Disease Modeling. [PDF]
Ahuja K +23 more
europepmc +1 more source

