Results 211 to 220 of about 86,512 (250)
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Oligodendrocytes and Alzheimer's disease
International Journal of Neuroscience, 2015Extensive evidence has indicated that the breakdown of myelin is associated with Alzheimer's disease (AD) since the vulnerability of oligodendrocytes under Alzheimer's pathology easily induces the myelin breakdown and the loss of the myelin sheath which might be the initiating step in the changes of the earliest stage of AD prior to appearance of ...
Zhiyou, Cai, Ming, Xiao
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The oligodendrocytic junctional complex
Cell and Tissue Research, 1978The junctional complex of oligodendrocytes was studied by means of different electron microscopical techniques. This complex is composed of the following junctional membrane formations: 1) tight junctional domains in the oligodendrocytic membrane near the some of the cells, 2) fasciae occludentes or focal tight junctions on the outer oligodendrocytic ...
R, Dermietzel, D, Schünke, A, Leibstein
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Tight junctions of oligodendrocytes
Cell and Tissue Research, 1977Freeze-fracture replicas of the rat corpus callosum revealed prominent junctional strands in fractured cell membranes of the somata of oligodendrocytes. The junctional strands were characterized by an elaborate system of straight or slightly undulating rows of linear aggregates of particles or ridges in the P face and furrows in the E face.
E, Tani, T, Itagaki, M, Nakano
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Expression of plasmolipin in oligodendrocytes
Journal of Neuroscience Research, 1991AbstractPlasmolipin is a plasma membrane proteolipid which has recently been described as a component of myelin (Cochary et al.: Journal of Neurochemistry 55:602–610, 1990). The present study reports the expression and localization of plasmolipin in primary glial cultures and secondary oligooendrocyte cultures.
I, Fischer +3 more
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Regulation of oligodendrocyte development
Molecular Neurobiology, 1998Oligodendrocytes are the cells responsible for the formation of myelin in the central nervous system. Recent studies demonstrated that cells of the oligodendrocyte lineage initially arise in distinct regions of the ventricular zone during early development.
D M, Orentas, R H, Miller
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Oligodendrocyte degeneration in AD
Neurobiology of Aging, 2004Most would agree with a description of Alzheimer’s disease (AD) primarily as a degeneration of the cerebral cortex. As a result, much laboratory research in the past decade has focused on the cell death mechanisms of neurons. However, it may be time broaden the focus of AD research to include dysfunction of the tracts that connect cortical areas.
G T, Whitman, C W, Cotman
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Regulators of Oligodendrocyte Differentiation
Cold Spring Harbor Perspectives in BiologyMyelination has evolved as a mechanism to ensure fast and efficient propagation of nerve impulses along axons. Within the central nervous system (CNS), myelination is carried out by highly specialized glial cells, oligodendrocytes. The formation of myelin is a prolonged aspect of CNS development that occurs well into adulthood in humans, continuing ...
Ben, Emery, Teresa L, Wood
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Oligodendrocytes and Microglia: Key Players in Myelin Development, Damage and Repair
Biomolecules, 2021Ilias Kalafatakis, Domna Karagogeos
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Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain
Cell Metabolism, 2020Mikael Simons +2 more
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