Results 221 to 230 of about 114,630 (300)

A posttranslational proteomic survey of a single anatomically preserved human 20‐week postconception brain

Journal of Anatomy, EarlyView.
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera, H. Bogetofte, P. Jensen, R. Hussain, S. A. Nischal, L. Rihova, G. J. Clowry, M. R. Larsen, Z. Molnár, B. C. Carlyle   +9 more
wiley   +1 more source

Myelin sheaths in the central nervous system can withstand damage and dynamically remodel. [PDF]

Science
Arafa D, van de Korput J, Braaker PN, Higgins KP, Meijns NRC, Marshall-Phelps KLH, Meng J, Soong D, Scalia E, Lathem K, Keatinge M, Richmond C, Klingseisen A, Main M, Neely SA, Hampton DW, Duncan GJ, Schenk GJ, Groot ML, Chandran S, Emery B, Luchicchi A, Kole MHP, Williams AC, Lyons DA.   +24 more
europepmc   +1 more source

Inflammatory Mediators Both Directly and Indirectly Promote Microglial Proliferation. [PDF]

Glia
Hammond BP, Hahn E, Lee KV, Kerr BJ, Plemel JR.   +4 more
europepmc   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Journal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads, Megan H. Hagenauer, Jinglin Xiong, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Elizabeth Flandreau, Stanley Watson Jr., Huda Akil   +8 more
wiley   +1 more source

Myelin is repaired by constitutive differentiation of oligodendrocyte progenitors. [PDF]

Science
Mironova YA, Dang B, Heo D, Xu YKT, Hsu AY, Eugenin von Bernhardi J, Molina-Castro GC, Kim AA, Lin JP, Reich DS, Bergles DE.   +10 more
europepmc   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles‐Associated DNA Triggers Inflammation by Inducing IL‐6 in Astrocytes

Molecular Oral Microbiology, EarlyView.
Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai, Kaya Yoshida, Yuka Hiroshima, Ayu Ikuta, Mariko Seyama, Yuta Uemura, Hiromichi Yumoto, Kazumi Ozaki   +7 more
wiley   +1 more source

Single-cell characterization of the adult male hippocampus suggests a prominent, and cell-type specific, role for Nrgn and Sgk1 in response to a social stressor. [PDF]

Mol Psychiatry
De Donno C, Lopez JP, Luecken MD, Kos A, Brivio E, Bordes J, Yang H, Deussing JM, Schmidt MV, Theis FJ, Chen A.   +10 more
europepmc   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Neurological fallout of hyperglycemia: A case report of a rare presentation of osmotic demyelination syndrome. [PDF]

Qatar Med J
Gupta R, Sachar C, Kaktyan P.
europepmc   +1 more source

Internalization of Exogenous Myelin by Oligodendroglia Promotes Lineage Progression. [PDF]

Glia
Peiró-Moreno C, Chara JC, Marshall-Phelps K, Ugarte-Arakistain I, Calovi S, De Almeida RG, Domercq M, Matute C.   +7 more
europepmc   +1 more source