Results 91 to 100 of about 15,454 (234)

Plant mitochondria possess a short-patch base excision DNA repair pathway [PDF]

, 2009
Despite constant threat of oxidative damage, sequence drift in mitochondrial and chloroplast DNA usually remains very low in plant species, indicating efficient defense and repair.
Boesch, Pierre, Cosset, Anne, Dietrich, André, Ibrahim, Noha, Paulus, François, Tarasenko, Vladislav   +5 more
core   +2 more sources

Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells

Journal of Lipid Research, 2004
High glucosylceramide synthase (GCS) activity is one factor contributing to multidrug resistance (MDR) in breast cancer. Enforced GCS overexpression has been shown to disrupt ceramide-induced apoptosis and to confer resistance to doxorubicin.
Yong-Yu Liu, Tie Yan Han, Jing Yuan Yu, Arie Bitterman, Ahn Le, Armando E. Giuliano, Myles C. Cabot   +6 more
doaj  

Gas-phase dissociation of oligoribonucleotides and their analogs studied by electrospray ionization tandem mass spectrometry [PDF]

, 2018
Oligoribonucleotides (RNA) and modified oligonucleotides were subjected to low-energy collision-induced dissociation in a hybrid quadrupole time-of-flight mass spectrometer to investigate their fragmentation pathways.
Schürch, Stefan, Tromp, Jan
core  

Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions [PDF]

, 1989
Sindbis virus mutant ts103 is aberrant in the assembly of virus particles. During virus budding, proper nucleocapsid-glycoprotein interactions fail to occur such that particles containing many nucleocapsids are formed, and the final yield of virus is low.
Hahn, Chang S., Lenches, Edith M., Rice, Charles M., Strauss, Ellen G., Strauss, James H.   +4 more
core  

G-quadruplex DNA aptamers and their ligands: Structure, function and application [PDF]

, 2012
Highly specific and tight-binding nucleic acid aptamers have been selected against a variety of molecular targets for over 20 years. A significant proportion of these oligonucleotides display G-quadruplex structures, particularly for DNA aptamers, that ...
Shum, KT, Tanner, JA, Tucker, WO
core   +1 more source

Sequence-specific cleavage of double helical DNA by triple helix formation [PDF]

, 1987
Homopyrimidine oligodeoxyribonucleotides with EDTA-Fe attached at a single position bind the corresponding homopyrimidine-homopurine tracts within large double-stranded DNA by triple helix formation and cleave at that site.
Dervan, Peter B., Moser, Heinz E.
core   +1 more source

Role of apurinic sites in the resistance of methylated oligodeoxyribonucleotides to degradation by spleen exonuclease [PDF]

, 1976
G. P Margison, P. J O'Connor, A Cornish-Bowden   +2 more
openalex   +1 more source

Application of 2-cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite forin situpreparation of deoxyribonucleoside phosphoramidites and their use in polymer-supported synthesis of oligodeoxyribonucleotides [PDF]

, 1986
John Nielsen, Michael Taagaard, J. E. MARUGG, Jacques H. van Boom, Otto Dahl   +4 more
openalex   +1 more source

Efficient cut and paste: directional oligodeoxynucleotide-based targeted insertion (DOTI) as a precise genome-editing method. [PDF]

Plant Cell, 2023
Sanchez-Muñoz R.
europepmc   +1 more source

Mass Spectrometric Analysis of the Active Site Tryptic Peptide of Recombinant O⁶-Methylguanine-DNA Methyltransferase Following Incubation with Human Colorectal DNA Reveals the Presence of an O⁶-Alkylguanine Adductome. [PDF]

Chem Res Toxicol, 2023
Abdelhady R, Senthong P, Eyers CE, Reamtong O, Cowley E, Cannizzaro L, Stimpson J, Cain K, Wilkinson OJ, Williams NH, Barran PE, Margison GP, Williams DM, Povey AC.   +13 more
europepmc   +1 more source