Results 101 to 110 of about 11,432 (197)
, 1989 We report that a double-stranded DNA template can direct the sequence-specific formation of a phosphodiester linkage between oligodeoxyribonucleotides in aqueous solution by juxtaposing the termini head-to-tail in a triple-helical complex (Figure 1).
Dervan, Peter B., Luebke, Kevin J.
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The Reactivity of the 5-Hydroxy-5,6-dihydrothymidin-6-yl Radical in Oligodeoxyribonucleotides
, 2016 Hydroxyl radical can be induced from Fenton reaction or γ radiolysis of water. It can add preferentially to the C5 position of thymidine to give the 5-hydroxy-5,6-dihydrothymidin-6-yl radical.
Qibin Zhang (8698), Yinsheng Wang (8699)
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, 1983 d-GGAATTCC (XI) was prepared by phosphomonotriazolide method in solution. Synthesis of oligodeoxyribonucleotides by phosphite method in solution using methyl phosphodichloridite was studied. Preparation of P-methyl esters of protected d-CA (XVII), d-CAT (
Hana Večerková, Jiří Smrt
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, 2008 Structural insight into DNA quadruplex structures formed by oligodeoxyribonucleotides 3'TG5'-5'GGGT3' (QS55) and 5'TG3'-3'GGGT5' (QS33) is presented. NMR anal. reveals that QS33 forms a parallel-like four-fold sym.
MAYOL, LUCIANO +4 more
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, 1986 The syntheses are described of two types of linker molecule useful for the specific attachment of non-radioactive labels such as biotin and fluorophores to the 5 ' terminus of synthetic oligodeoxyribonucleotides.
Michael J. Gait +2 more
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Phosphodiester-Mediated Reaction of Cisplatin with Guanine in Oligodeoxyribonucleotides
, 2016 The cancer chemotherapeutic agent cis-diamminedichloroplatinum(II) or cisplatin reacts primarily with guanines in DNA to form 1,2-Pt-GG and 1,3-Pt-GNG intrastrand cross-links and, to a lesser extent, G-G interstrand cross-links.
Meghan A. Campbell (1990066) +1 more
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, 1997 To detect potential intracellular binding sites for antisense oligodeoxyribonucleotides (ODN), 3'−fluorescence−tagged phosphodiester (P) and phosphorothioate (S) analogs of a series of model and vimentin and actin antisense ODN were applied to ...
Grueb, Sabine +14 more
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, 2015 Effects of background electrolyte pH, composition and concentration on the electrophoretic transport of short oligodeoxyribonucleotides (ODNs) in fused silica capillaries have been investigated in the presented study.
Vítová, Lada
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, 1970 The high degree of specificity of base interactions of complementary polynucleotides is a fundamental property of biological systems. Through interactions of this type, genetic information is able to flow, to succeeding generations by replication of the ...
Astell, Caroline Ruth
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