Results 91 to 100 of about 11,432 (197)

Chemical and enzymatic biotin-labeling of oligodeoxyribonucleotides

Nucleic Acids Research, 1985
Biotin has been converted to 2-(biotinylamido)ethanol and condensed to phosphorylated oligonucleotides in a solid phase synthesis. The 5'-biotinylated oligonucleotides were enzymatically coupled to other DNA fragments by T4 DNA ligase or T4 RNA ligase. The hybridization properties of such biotin-labeled oligonucleotide probes were studied.
Tomas Kempe, Wesley I. Sundquist, Flora Chow, Shiu-Lok Hu   +3 more
openaire   +3 more sources

The chemical end-ligation of homopyrimidine oligodeoxyribonucleotides within a DNA triple helix

, 1997
Background: Triple-helical nucleic acids, first reported in the late 1950s, are receiving attention for their possible involvement in controlling gene expression. Certain sequences of DNA are believed to form local triple-helical structures (H-form DNA),
Li, Tianhu, Nicolaou, K.C., Weinstein, David S.   +2 more
core   +1 more source

Interaction of the recombinant human methylpurine-DNA glycosylase (MPG protein) with oligodeoxyribonucleotides containing either hypoxanthine or abasic sites

, 1998
Methylpurine-DNA glycosylases (MPG proteins, 3-methyladenine-DNA glycosylases) excise numerous damaged bases from DNA during the first step of base excision repair.
Miao, Feng, O'Connor, Timothy R, Bouziane, Mohammed   +2 more
core   +1 more source

A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY SITE

, 2005
A NEW CLASS OF DNA QUADRUPLEX FORMED BY OLIGODEOXYRIBONUCLEOTIDES CONTAINING A 3'-3' OR 5'-5' INVERSION OF POLARITY ...
MAYOL, LUCIANO, VIRGILIO, ANTONELLA, ESPOSITO, VERONICA, RANDAZZO, ANTONIO, GALEONE, ALDO   +4 more
core  

3'-O-Formyl-(N-acyl)-2'-deoxyribonucleosides as building units in the synthesis of oligodeoxyribonucleotides

, 1982
5'-O-Dimethoxytrityl-(N-acyl)-2'-deoxyribonucleosides afford 3'-O-formyl-(N-acyl)-2'-deoxyribonucleosides Ia-Id by the action of formic acetic anhydride followed by the action of 80% aqueous acetic acid.
Jiří Smrt
core   +1 more source

Methods towards the incorporation of metal carbonyl complexes into oligodeoxyribonucleotides

, 1993
There has been considerable interest in the development of non-radioactively labeled oligodeoxyribonucleotides for use as (1) probes in molecular biology research, (2) medical diagnostic tools, and (3) agents for the investigation of protein/DNA ...
Dalla Riva Toma, Joan Marie
core  

Biochemical properties of phosphonoacetate and thiophosphonoacetate oligodeoxyribonucleotides

, 2003
Phosphorus-modi®ed phosphonoacetate and thio-phosphonoacetate oligodeoxyribonucleotides were chemically synthesized and their biochemical pro-perties evaluated.
David Sheehan, Marvin H. Caruthers, Benjamin Lunstad, Brian G. Stell, Douglas J. Dellinger, Christina M. Yamada   +5 more
core  

Comparison of controlled pore glass and Kieselguhr-polydimethylacrylamide composite as supports for solid-phase synthesis of 23-residue oligodeoxyribonucleotides in milligram amounts

, 1985
Two 23-residue oligodeoxyribonucleotides, corresponding to both strands of a DNA duplex at the OR3 site of bacteriophage λ, have been synthesized in good yields and in milligram quantities by a solid-phase phosphotriester method using two different ...
Minganti, Carlo, Ganesh, K. N., Sproat, Brian S., Gait, Michael J.   +3 more
core   +1 more source

The Synthesis of Oligodeoxyribonucleotides With Rna Ligase

, 1980
RNA ligase, isolated from bacteriophage T4-infected Escherichia coli catalyzes the ATP-dependent formation of a 3' (--->) 5'-phosphodiester bond between one oligonucleotide with a 3'-hydroxyl group (the acceptor molecule) and another with a 5 ...
Hinton, Deborah Meetze
core  

Cross-Linking Antisense Oligodeoxyribonucleotides with a Photoresponsive α‑Chloroaldehyde Moiety for RNA Point Mutations

, 2016
Because point mutations in GTPase-coding genes have been reported to be responsible for the transformation of cells, anticancer reagents that react effectively and sequence selectively with target RNAs having a point mutation are highly desired.
Yuki Nakata (1395616), Asako Yamayoshi (1368726), Yuta Sugihara (1395613), Akira Murakami (331566), Akio Kobori (1368729)   +4 more
core   +1 more source