Effective primer design for genotype and subtype detection of highly divergent viruses in large scale genome datasets [PDF]
Identification of microorganisms in a biological sample is a crucial step in diagnostics, pathogen screening, biomedical research, evolutionary studies, agriculture, and biological threat assessment.
Burak Demiralay, Tolga Can
doaj +2 more sources
Sequencing analysis of HPV-other type on an HPV DNA chip [PDF]
ObjectivesTo identify the specific human papillomavirus (HPV) genotypes from HPV-other type on an HPV DNA chip test by sequencing.MethodsAmong 13,600 women undergoing a routine gynecology examination including Pap smear and/or HPV test by DNA chip test ...
Min-Jeong Kim, Jin Ju Kim, Sunmie Kim
doaj +1 more source
Identification of genomic imbalances in oral clefts
Objective: This article presents a clinical and cytogenomic approach that focuses on the diagnosis of syndromic oral clefts (OCs). Methods: The inclusion criteria were individuals with OC presenting four or more minor signs and no major defects (non ...
Elaine Lustosa-Mendes +9 more
doaj +1 more source
Systematic validation and atomic force microscopy of non-covalent short oligonucleotide barcode microarrays. [PDF]
BACKGROUND: Molecular barcode arrays provide a powerful means to analyze cellular phenotypes in parallel through detection of short (20-60 base) unique sequence tags, or "barcodes", associated with each strain or clone in a collection.
Michael A Cook +6 more
doaj +1 more source
Genomic Profiling of Liver Cancer [PDF]
Development of liver cancers is driven largely by genomic alterations that deregulate signaling pathways, influencing growth and survival of cancer cells. Because of the hundreds or thousands of genomic/epigenomic alterations that have accumulated in the
Ju-Seog Lee
doaj +1 more source
Comparison of Analytical and Clinical Performance of HPV 9G DNA Chip, PANArray HPV Genotyping Chip, and Hybrid-Capture II Assay in Cervicovaginal Swabs [PDF]
Background: Human papillomavirus (HPV) infection can be detected by using several molecular methods, including Hybrid-Capture II (HC2) assay and variable HPV DNA chip tests, although each method has different sensitivities and specificities.
Ho Young Jung +5 more
doaj +1 more source
Molecular analysis of endocrine disruption in hornyhead turbot at wastewater outfalls in southern california using a second generation multi-species microarray. [PDF]
Sentinel fish hornyhead turbot (Pleuronichthysverticalis) captured near wastewater outfalls are used for monitoring exposure to industrial and agricultural chemicals of ~ 20 million people living in coastal Southern California.
Angert, Mila +15 more
core +8 more sources
Background Nonsyndromic cleft lip and/or without cleft palate (NSCL/P) with or without hypodontia is a common developmental aberration in humans and animals.
Norliana Ghazali +4 more
doaj +1 more source
Physico-chemical foundations underpinning microarray and next-generation sequencing experiments [PDF]
Hybridization of nucleic acids on solid surfaces is a key process involved in high-throughput technologies such as microarrays and, in some cases, next-generation sequencing (NGS).
A. Buhot +70 more
core +3 more sources
Expresión específica de los genes de la respuesta inflamatoria en subpoblaciones de macrófagos.
Como brazo efectivo de la respuesta inmune, los macrófagos reconocen, fagocitan y destruyen patógenos potenciales. También, coordinan respuestas adicionales del hospedero mediante la síntesis de un amplio rango de mediadores de la inflamación que, en ...
Vera María Ripoll +2 more
doaj +1 more source

