Results 1 to 10 of about 714,572 (311)
Carcinoma de mama: novos conceitos na classificação Breast cancer: new concepts in classification
Revista Brasileira de Ginecologia e Obstetrícia, 2008 O carcinoma de mama é a neoplasia maligna mais comum em mulheres. Estudos moleculares do carcinoma de mama, baseados na identificação do perfil de expressão gênica por meio do cDNA microarray, permitiram definir pelo menos cinco sub-grupos distintos ...
Daniella Serafin Couto Vieira +3 more
doaj +1 more source
Structural and functional-annotation of an equine whole genome oligoarray
BMC Bioinformatics, 2009 Background The horse genome is sequenced, allowing equine researchers to use high-throughput functional genomics platforms such as microarrays; next-generation sequencing for gene expression and proteomics.
Chowdhary Bhanu +4 more
doaj +1 more source
BMC Genomics, 2006 Background Eukaryotic replication origins exhibit different initiation efficiencies and activation times within S-phase. Although local chromatin structure and function influences origin activity, the exact mechanisms remain poorly understood.
Aparicio Oscar M +3 more
doaj +1 more source
Microarrays as a functional approach to the transcriptome [PDF]
, 2016 Knowing a cell’s transcriptome is a fundamental requisite in order to analyze its response to the environment. Microarrays have supposed a revolution on this field as they are able to yield an overview of gene expression at any environmental condition on
Barrionuevo Moreno, Ignacio +1 more
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Quality assessment for short oligonucleotide microarray data [PDF]
arXiv, 2007 Quality of microarray gene expression data has emerged as a new research topic. As in other areas, microarray quality is assessed by comparing suitable numerical summaries across microarrays, so that outliers and trends can be visualized, and poor quality arrays or variable quality sets of arrays can be identified.
arxiv
Limit Theorems for Hybridization Reactions on Oligonucleotide Microarrays [PDF]
arXiv, 2008 We derive herein the limiting laws for certain stationary distributions of birth-and-death processes related to the classical model of chemical adsorption-desorption reactions due to Langmuir. The model has been recently considered in the context of a hybridization reaction on an oligonucleotide DNA microarray.
arxiv
RPA: Probabilistic analysis of probe performance and robust summarization [PDF]
arXiv, 2011 Probe-level models have led to improved performance in microarray studies but the various sources of probe-level contamination are still poorly understood. Data-driven analysis of probe performance can be used to quantify the uncertainty in individual probes and to highlight the relative contribution of different noise sources.
arxiv
A new formalism for calculation of the partition function of single stranded nucleic acids [PDF]
arXiv, 2005 A new formalism for calculation of the partition function of single stranded nucleic acids is presented. Secondary structures and the topology of structure elements are the level of resolution that is used. The folding model deals with matches, mismatches, symmetric and asymmetric interior loops, stacked pairs in loop and dangling end regions, multi ...
arxiv
Mutation model for oligonucleotides fitting a Yule distribution [PDF]
arXiv, 2004 A spin chain, describing a nucleotides sequence, is identified by the labels of a vector state of an irreducible representation of U_q->0(sl2). A master equation for the distribution function is written, where the intensity of the one-spin flip is assumed to depend on the variation of the labels.
arxiv
Aptamers in oncology: a diagnostic perspective [PDF]
, 2008 Nucleic acid sequences can produce a wide variety of three-dimensional conformations. Some of these structural forms are able to interact with proteins and small molecules with high affinity and specificity.
Khan, Huma, Missailidis, Sotiris
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