Results 1 to 10 of about 708,274 (274)

Enhanced high density oligonucleotide array-based sequence analysis using modified nucleoside triphosphates [PDF]

Nucleic Acids Research, 1998
Pairs of high density oligonucleotide arrays (DNA chips) consisting of >96 000 oligonucleotides were designed to screen the entire 5.53 kb coding region of the hereditary breast and ovarian cancer BRCA1 gene for all possible sequence changes in the ...
J. Hacia
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Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1999
The p53 gene was sequenced in 100 primary human lung cancers by using direct dideoxynucleotide cycle sequencing and compared with sequence analysis by using the p53 GeneChip assay.
Steven A. Ahrendt, Sarel Halachmi, John T. Chow, Wu Li, Naomi Halachmi, Stephen C. Yang, Scott L. Wehage, Jin Jen, David Sidransky   +8 more
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Optimizing copy number variation analysis using genome-wide short sequence oligonucleotide arrays [PDF]

Nucleic Acids Research, 2010
The detection of copy number variants (CNV) by array-based platforms provides valuable insight into understanding human diversity. However, suboptimal study design and data processing negatively affect CNV assessment.
Derek A. Oldridge, Samprit Banerjee, Sunita R. Setlur, Andrea Sboner, Francesca Demichelis   +4 more
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Light-generated oligonucleotide arrays for rapid DNA sequence analysis.

Proceedings of the National Academy of Sciences of the United States of America, 1994
In many areas of molecular biology there is a need to rapidly extract and analyze genetic information; however, current technologies for DNA sequence analysis are slow and labor intensive.
Ann C. Pease, Dennis Solas, Elizabeth J. Sullivan, Mark T.D. Cronin, Christopher P. Holmes, Stephen P. A. Fodor   +5 more
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Experimental optimization of probe length to increase the sequence specificity of high-density oligonucleotide microarrays

BMC Genomics, 2007
Background High-density oligonucleotide arrays are widely used for analysis of genome-wide expression and genetic variation. Affymetrix GeneChips – common high-density oligonucleotide arrays – contain perfect match (PM) and mismatch (MM) probes generated
Kashiwagi Akiko, Furusawa Chikara, Ono Naoaki, Suzuki Shingo, Yomo Tetsuya   +4 more
doaj   +2 more sources

Identification of a deep intronic mutation in the COL6A2 gene by a novel custom oligonucleotide CGH array designed to explore allelic and genetic heterogeneity in collagen VI-related myopathies

BMC Medical Genetics, 2010
Background Molecular characterization of collagen-VI related myopathies currently relies on standard sequencing, which yields a detection rate approximating 75-79% in Ullrich congenital muscular dystrophy (UCMD) and 60-65% in Bethlem myopathy (BM ...
Merlini Luciano, Bertini Enrico, Mercuri Eugenio, Grumati Paolo, Fabris Marina, Sabatelli Patrizia, Urciuolo Anna, Martoni Elena, Neri Marcella, Bovolenta Matteo, Bonaldo Paolo, Ferlini Alessandra, Gualandi Francesca   +12 more
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Sequencing analysis of HPV-other type on an HPV DNA chip [PDF]

Obstetrics & Gynecology Science, 2018
ObjectivesTo identify the specific human papillomavirus (HPV) genotypes from HPV-other type on an HPV DNA chip test by sequencing.MethodsAmong 13,600 women undergoing a routine gynecology examination including Pap smear and/or HPV test by DNA chip test ...
Min-Jeong Kim, Jin Ju Kim, Sunmie Kim
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Systematic validation and atomic force microscopy of non-covalent short oligonucleotide barcode microarrays. [PDF]

PLoS ONE, 2008
BACKGROUND: Molecular barcode arrays provide a powerful means to analyze cellular phenotypes in parallel through detection of short (20-60 base) unique sequence tags, or "barcodes", associated with each strain or clone in a collection.
Michael A Cook, Chi-Kin Chan, Paul Jorgensen, Troy Ketela, Daniel So, Mike Tyers, Chi-Yip Ho   +6 more
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Genomic Profiling of Liver Cancer [PDF]

Genomics & Informatics, 2013
Development of liver cancers is driven largely by genomic alterations that deregulate signaling pathways, influencing growth and survival of cancer cells. Because of the hundreds or thousands of genomic/epigenomic alterations that have accumulated in the
Ju-Seog Lee
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Comparison of Analytical and Clinical Performance of HPV 9G DNA Chip, PANArray HPV Genotyping Chip, and Hybrid-Capture II Assay in Cervicovaginal Swabs [PDF]

Journal of Pathology and Translational Medicine, 2016
Background: Human papillomavirus (HPV) infection can be detected by using several molecular methods, including Hybrid-Capture II (HC2) assay and variable HPV DNA chip tests, although each method has different sensitivities and specificities.
Ho Young Jung, Hye Seung Han, Hyo Bin Kim, Seo Young Oh, Sun-Joo Lee, Wook Youn Kim   +5 more
doaj   +1 more source