Drug-induced anti-Ro positive subacute cutaneous lupus in a man treated with olmesartan [PDF]
, 2019 A 66-year-old man presented to the outpatient dermatology clinic with a chief complaint of a pruritic rash on his upper trunk and proximal upper extremities, which had been present for three weeks.
Farsi, Maheera +4 more
core
Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, EarlyView.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
IN SILICO EVALUATION OF ANGIOTENSIN II RECEPTOR ANTAGONIST’S PLASMA PROTEIN BINDING USING COMPUTED MOLECULAR DESCRIPTORS [PDF]
, 2014 The discovery of new pharmacologically active substances and drugs modeling led to necessity of predicting drugs properties and its ADME data. Angiotensin II receptor antagonists are a group of pharmaceuticals which modulate the renin-angiotensin ...
Jadranka Odović +1 more
core +1 more source
Steatocystoma Multiplex Suppurativa—A Case Report and Review of Treatments
Australasian Journal of Dermatology, EarlyView.ABSTRACT We report a case of Steatocystoma Multiplex Suppurativa (SMS), a rare condition that can mimic hidradenitis suppurativa (HS). We also present a review of the surgical and medical therapies, including potential biologic agents.
Justin Tam Vu, Alexis Daniel Lara Rivero
wiley +1 more source
Combination Therapy with Olmesartan and Amlodipine in the Treatment of Hypertension
Pharmaceuticals, 2009 Background: Combination therapy with antihypertensive agents utilises different mechanisms of action and may be responsible for a more effective decrease in blood pressure.
Menco G. Niemeijer, Ton J. Cleophas
doaj +1 more source
Health-related quality of life impact of a triple combination of olmesartan medoxomil, amlodipine besylate and hydrochlorotiazide in subjects with hypertension [PDF]
, 2015 Background A post-hoc analysis was performed on the data from a 54 weeks phase III study (ClinicalTrials.gov identifier: NCT00923091) to measure changes in the health-related quality of life (HRQoL) of 2,690 patients aged ≥18 with moderate-to-severe ...
Brazier, J.E. +4 more
core +2 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
ADMA, SDMA and L-arginine may be novel targets in pharmacotherapy for complications due to cardiopulmonary bypass [PDF]
Journal of Medical Biochemistry, 2017 Background: In this study, the effects of olmesartan therapy on asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA), L-arginine and inducible nitric oxide synthase (iNOS) levels were investigated in patients undergoing cardiopulmonary ...
Kahraman Aydin +2 more
doaj
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials [PDF]
, 2017 There is no treatment for the myelin loss in multiple sclerosis, ultimately resulting in the axonal degeneration that leads to the progressive phase of the disease.
Agresti, C. +11 more
core +2 more sources