Results 31 to 40 of about 370,247 (301)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Omega 3 y plasticidad neuronal
Práctica Familiar RuralEl omega-3, especialmente los ácidos grasos docosahexaenoico (DHA) y eicosapentaenoico (EPA), desempeña un papel crucial en la neuroplasticidad, la capacidad del cerebro para reorganizarse y formar nuevas conexiones neuronales en respuesta a ...
Andrea Alexandra Tufiño Aguilar +1 more
doaj +1 more source
Needs in omega 3 and ocular pathologies
Oléagineux, Corps gras, Lipides, 2011 Life expectancy at birth has regularly increased decade after decade, especially since the beginning of the 20th century: 15 years have been gained over the past 50 years.
Bretillon Lionel +5 more
doaj +1 more source
Omega-3 Polyunsaturated Fatty Acids and Heart Rate Variability [PDF]
, 2011 Omega-3 polyunsaturated fatty acids (PUFA) may modulate autonomic control of the heart because omega-3 PUFA is abundant in the brain and other nervous tissue as well as in cardiac tissue.
Jeppe Hagstrup Christensen
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
RBC and WBC fatty acid composition following consumption of an omega 3 supplement: Lessons for future clinical trials [PDF]
, 2010 Background: Results from increasing numbers of in vitro and in vivo studies have demonstrated that omega 3 fatty acids incorporated in cell culture media or in the diet of the animals can suppress the growth of cancers.
Witte, Theodore R. +3 more
core +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The role of fatty acids in attention deficit hyperactivity disorder
Acta Medica Alanya, 2022 Attention deficit hyperactivity disorder (ADHD) is a childhood-onset disorder that affects 5% to 12% of children worldwide. Etiological factors, including nutrition, contribute to this disease, which is characterized by inattention, impulsivity and ...
Fatih Gültekin +2 more
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
IDENTIFICATION OF PHYTOPLANKTON TYPES IN TAMBAK BANDENG WITH HIGH QUALITY OF OMEGA-3
JFMR-Journal of Fisheries and Marine Research, 2019 Microalgae as a source of nutrients, can be a good alternative to the use of high-level organisms. The abundant omega 3 content in plankton, especially phytoplankton, needs to be conducted research on the identification of the types of phytoplankton in ...
Endang Yuli Herawati
doaj +1 more source