A Four-Antigen Mixture for Rapid Assessment of Onchocerca volvulus Infection [PDF]
PLoS Neglected Tropical Diseases, 2009 Onchocerciasis, an infection caused by the filarial nematode Onchocerca volvulus, is a major public health concern. Given the debilitating symptoms associated with onchocerciasis and concerns about recrudescence in areas of previous onchocerciasis ...
Peter D Burbelo, Thomas B Nutman
exaly +4 more sources
Onchocerca volvulus-specific antibody and cellular responses in onchocerciasis patients treated annually with ivermectin for 30 years and exposed to parasite transmission in central Togo [PDF]
PLoS Neglected Tropical Diseases, 2022 Background Annual mass drug administrations (MDA) of ivermectin will strongly reduce Onchocerca volvulus microfilariae (mf) in the skin and in the onchocerciasis patients’ eyes. Ivermectin treatment will also affect the expression of immunity in patients,
Saskia I. Johanns +10 more
doaj +3 more sources
Extracellular Onchocerca-derived small RNAs in host nodules and blood
Parasites and Vectors, 2015 Background microRNAs (miRNAs), a class of short, non-coding RNA can be found in a highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by parasitic nematodes in exosomes and have been detected in the serum of murine and ...
Juan F Quintana +2 more
exaly +2 more sources
Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates [PDF]
Vaccines, 2023 Onchocerciasis remains a debilitating neglected tropical disease. Due to the many challenges of current control methods, an effective vaccine against the causative agent Onchocerca volvulus is urgently needed.
Nathan M. Ryan +17 more
doaj +2 more sources
Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan [PDF]
Journal of Epidemiology and Global HealthBackground Onchocerciasis, a neglected tropical disease (NTD) caused by Onchocerca volvulus, is hyperendemic in many parts of Africa, including South Sudan.
Chiara Trevisan +7 more
doaj +2 more sources
The Functional Parasitic Worm Secretome: Mapping the Place of Onchocerca volvulus Excretory Secretory Products [PDF]
Pathogens, 2020 Nematodes constitute a very successful phylum, especially in terms of parasitism. Inside their mammalian hosts, parasitic nematodes mainly dwell in the digestive tract (geohelminths) or in the vascular system (filariae). One of their main characteristics
Luc Vanhamme +3 more
doaj +2 more sources
Observations onOnchocerca Volvulus
Annals of Tropical Medicine & Parasitology, 1922 J. W. S. Macfie, J. F. Corson
openalex +4 more sources
Onchocerca volvulus Mimicking Metastatic Breast Carcinoma. [PDF]
Am J Trop Med Hyg, 2020 Nava VE, Ejilemele AA.
europepmc +4 more sources
BMC Microbiology, 2021 Background During the last two decades research on animal filarial parasites, especially Onchocerca ochengi, infecting cattle in savanna areas of Africa revealed that O.
Ngwafu Nancy Ngwasiri +9 more
doaj +1 more source
The onchocerciasis hypothesis of nodding syndrome.
PLoS Neglected Tropical Diseases, 2023 Nodding syndrome (NS) is a phenotypic presentation of onchocerciasis-associated epilepsy (OAE). OAE is an important public health problem in areas with high ongoing Onchocerca volvulus transmission.
Robert Colebunders +2 more
doaj +1 more source