Results 1 to 10 of about 26,538 (247)

Ongoing Transmission of Onchocerca volvulus after 25 Years of Annual Ivermectin Mass Treatments in the Vina du Nord River Valley, in North Cameroon. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Recent reports of transmission interruption of Onchocerca volvulus, the causing agent of river blindness, in former endemic foci in the Americas, and more recently in West and East Africa, raise the question whether elimination of this ...
Albert Eisenbarth, Mbunkah Daniel Achukwi, Alfons Renz   +2 more
doaj   +4 more sources

Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: Relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment [PDF]

BMC Infectious Diseases, 2020
Background Ivermectin is an excellent microfilaricide against Onchocerca volvulus. However, in some regions, long term use of ivermectin has resulted in sub-optimal responses to the treatment.
Raphael Awah Abong, Glory Ngongeh Amambo, Patrick W. Chounna Ndongmo, Abdel Jélil Njouendou, Ritter Manuel, Amuam Andrew Beng, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Fanny Fri Fombad, Theobald Mue Nji, Peter Ivo Enyong, Catherine B. Poole, Kenneth Pfarr, Achim Hoerauf, Clotilde K. S. Carlow, Samuel Wanji   +16 more
semanticscholar   +4 more sources

Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening

PLoS Neglected Tropical Diseases, 2021
Background Infections with Onchocerca volvulus nematodes remain a threat in Sub-Saharan Africa after three decades of ivermectin mass drug administration.
Narcisse Victor Tchamatchoua Gandjui, Abdel Jélil Njouendou, Eric Njih Gemeg, Fanny Fri Fombad, Manuel Ritter, Chi Anizette Kien, Valerine C. Chunda, Jerome Fru, Mathias Eyong Esum, Marc P. Hübner, Peter Enyong, Achim Hoerauf, Samuel Wanji   +12 more
openalex   +3 more sources

Not every worm wrapped around a stick is a guinea worm: a case of Onchocerca volvulus mimicking Dracunculus medinensis [PDF]

Parasites & Vectors, 2015
Background Despite being certified guinea worm free in 2007, Cameroon continues surveillance efforts to ensure rapid verification of any suspected reoccurrence.
Eta Ngole Mbong, Gerald Etapelong Sume, Flaubert Danbe, Walter Kang Kum, Valeri Oben Mbi, André Arsène Bita Fouda, Peter Atem   +6 more
doaj   +2 more sources

Pharmacokinetics of oral moxidectin in individuals with Onchocerca volvulus infection. [PDF]

PLoS Negl Trop Dis, 2022
Background Onchocerciasis (“river blindness”), is a neglected tropical disease caused by the filarial nematode Onchocerca volvulus and transmitted to humans through repeated bites by infective blackflies of the genus Simulium.
Tan B, Opoku N, Attah SK, Awadzi K, Kuesel AC, Lazdins-Helds J, Rayner C, Ryg-Cornejo V, Sullivan M, Fleckenstein L.   +9 more
europepmc   +2 more sources

Onchocerca volvulus and epilepsy: A comprehensive review using the Bradford Hill criteria for causation

PLoS Neglected Tropical Diseases, 2021
Background The possibility that onchocerciasis may cause epilepsy has been suggested for a long time, but thus far, an etiological link has not been universally accepted.
Robert Colebunders, Alfred K Njamnshi, An Hotterbeekx   +2 more
exaly   +2 more sources

Urine metabolites for the identification of Onchocerca volvulus infections in patients from Cameroon. [PDF]

Parasit Vectors, 2021
Background The tropical disease onchocerciasis (river blindness), caused by Onchocerca volvulus filarial nematodes, is targeted for elimination by mass treatment with nematocidal and antimicrobial drugs. Diagnosis of O.
Wewer V, Peisker H, Gutbrod K, Al-Bahra M, Menche D, Amambo NG, Fombad FF, Njouendou AJ, Pfarr K, Wanji S, Hoerauf A, Dörmann P.   +11 more
europepmc   +2 more sources

Nodding syndrome is unlikely to be an autoimmune reaction to leiomodin-1 after infection by Onchocerca volvulus [PDF]

Biochemistry and Biophysics Reports, 2023
Nodding syndrome is a neurological disease of children in northern Uganda. Infection with the nematode parasite Onchocerca volvulus has been epidemiologically implicated as the cause of the disease.
Kenneth G. Kodja, Sylvester Onzivua, David L. Kitara, Amanda Fong, Patrick Kim, Michael S. Pollanen   +5 more
doaj   +2 more sources

Application of loop mediated isothermal amplification (LAMP) assays for the detection of <i>Onchocerca volvulus</i>, <i>Loa loa</i> and <i>Mansonella perstans</i> in humans and vectors. [PDF]

Front Trop Dis, 2023
Conventional diagnosis of filarial infections is based on morphological identification of microfilariae using light microscopy and requires considerable expertise, is time-consuming, and can be subjective.
Amambo GN, Innocentia N, Abong RA, Fombad FF, Njouendou AJ, Nietcho F, Ekanya R, Kien CA, Ebai R, Lenz B, Ritter M, Esum ME, Deribe K, Cho JF, Beng AA, Enyong PI, Li Z, Hübner MP, Pfarr K, Hoerauf A, Carlow C, Wanji S.   +21 more
europepmc   +2 more sources

Epilepsy in Onchocerca volvulus Sero-Positive Patients From Northern Uganda—Clinical, EEG and Brain Imaging Features

Frontiers in Neurology, 2021
Globally, epilepsy is the most common chronic neurological disorder. The incidence in sub-Saharan Africa is 2-3 times higher than that in high income countries.
Rodney Ogwang, Rodney Ogwang, Rodney Ogwang, Albert Ningwa, Albert Ningwa, Pamela Akun, Pamela Akun, Paul Bangirana, Ronald Anguzu, Ronald Anguzu, Ronald Anguzu, Rajarshi Mazumder, Noriko Salamon, Oliver Johannes Henning, Charles R. Newton, Charles R. Newton, Catherine Abbo, Amos Deogratius Mwaka, Kevin Marsh, Richard Idro, Richard Idro, Richard Idro   +21 more
doaj   +2 more sources