Not every worm wrapped around a stick is a guinea worm: a case of Onchocerca volvulus mimicking Dracunculus medinensis [PDF]
Parasites & Vectors, 2015 Background Despite being certified guinea worm free in 2007, Cameroon continues surveillance efforts to ensure rapid verification of any suspected reoccurrence.
Eta Ngole Mbong +6 more
doaj +2 more sources
Nodding syndrome is unlikely to be an autoimmune reaction to leiomodin-1 after infection by Onchocerca volvulus [PDF]
Biochemistry and Biophysics Reports, 2023 Nodding syndrome is a neurological disease of children in northern Uganda. Infection with the nematode parasite Onchocerca volvulus has been epidemiologically implicated as the cause of the disease.
Kenneth G. Kodja +5 more
doaj +2 more sources
Prevalence and risk factors for Active Convulsive Epilepsy in Kintampo, Ghana [PDF]
The Pan African Medical Journal, 2015 INTRODUCTION: epilepsy is common in sub-Saharan Africa, but there is little data in West Africa, to develop public health measures for epilepsy in this region.
Kenneth Ayuurebobi Ae-Ngibise +9 more
doaj +5 more sources
Onchocerca volvulus-specific antibody and cellular responses in onchocerciasis patients treated annually with ivermectin for 30 years and exposed to parasite transmission in central Togo [PDF]
PLoS Neglected Tropical Diseases, 2022 Background Annual mass drug administrations (MDA) of ivermectin will strongly reduce Onchocerca volvulus microfilariae (mf) in the skin and in the onchocerciasis patients’ eyes. Ivermectin treatment will also affect the expression of immunity in patients,
Saskia I. Johanns +10 more
doaj +3 more sources
Crystal structure of N-terminally hexahistidine-tagged Onchocerca volvulus macrophage migration inhibitory factor-1. [PDF]
Acta Crystallogr F Struct Biol CommunN‐terminally hexahistidine‐tagged O. volvulus macrophage migration inhibitory factor‐1 has a unique jellyfish‐like structure with the prototypical macrophage migration inhibitory factor trimer as the `head' and a C‐terminal extension as the `tail'.Onchocerca volvulus causes blindness, onchocerciasis, skin infections and devastating neurological ...
Kimble AD +10 more
europepmc +2 more sources
Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum. [PDF]
PLoS Neglected Tropical Diseases, 2018 BackgroundThe study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection.
John B Patton +7 more
doaj +4 more sources
Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates [PDF]
Vaccines, 2023 Onchocerciasis remains a debilitating neglected tropical disease. Due to the many challenges of current control methods, an effective vaccine against the causative agent Onchocerca volvulus is urgently needed.
Nathan M. Ryan +17 more
doaj +2 more sources
A preliminary analysis of the population genetics and molecular phylogenetics of Onchocerca volvulus (Nematoda: Filarioidea) using nuclear ribosomal second internal transcribed spacer sequences [PDF]
Memorias do Instituto Oswaldo Cruz, 2007 Nuclear internal transcribed spacer 2 (ITS2) rDNA sequences were used for a molecular phylogenetics analysis of five Onchocerca species. The sister species of the human parasite O. volvulus was found to be the cattle parasite O.
Ramiro Morales-Hojas +2 more
doaj +4 more sources
Phylogenetic relationships of the Wolbachia of nematodes and arthropods. [PDF]
PLoS Pathogens, 2006 Wolbachia are well known as bacterial symbionts of arthropods, where they are reproductive parasites, but have also been described from nematode hosts, where the symbiotic interaction has features of mutualism.
Katelyn Fenn +6 more
doaj +6 more sources
Comparison of Structural Changes in Nodding Syndrome and Other Epilepsies Associated With Onchocerca volvulus. [PDF]
Neurol Neuroimmunol Neuroinflamm, 2023 Mazumder R +13 more
europepmc +3 more sources