Results 11 to 20 of about 5,473 (218)

Crystal structure of N-terminally hexahistidine-tagged Onchocerca volvulus macrophage migration inhibitory factor-1. [PDF]

Acta Crystallogr F Struct Biol Commun
N‐terminally hexahistidine‐tagged O. volvulus macrophage migration inhibitory factor‐1 has a unique jellyfish‐like structure with the prototypical macrophage migration inhibitory factor trimer as the `head' and a C‐terminal extension as the `tail'.Onchocerca volvulus causes blindness, onchocerciasis, skin infections and devastating neurological ...
Kimble AD, Dawson OCO, Liu L, Subramanian S, Cooper A, Battaile K, Craig J, Harmon E, Myler P, Lovell S, Asojo OA.   +10 more
europepmc   +2 more sources

A rare case of cutaneous onchocerciasis in North-East India, review of literature

Indian Dermatology Online Journal, 2020
Onchocerca volvulus is a spirurid nematode that mainly affects the rural poor of Sub-Saharan Africa, Yemen, and parts of Central and South America. River blindness caused by Onchocerca volvulus is considered to be the second most common infectious cause ...
M M Pasha, Chetan C Patil, M Tanuja, Debdeep Mitra   +3 more
doaj   +1 more source

Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.

PLoS Pathogens, 2021
Onchocerciasis (river blindness), caused by the filarial worm Onchocerca volvulus, is a neglected tropical disease mostly affecting sub-Saharan Africa and is responsible for >1.3 million years lived with disability. Current control relies almost entirely
Germanus S Bah, Sebastian Schneckener, Steffen R Hahnel, Nicolas H Bayang, Helena Fieseler, Gabriele M Schmuck, Ralph Krebber, Anouk Sarr, Carsten Terjung, Henrietta F Ngangyung, David D Ekale, Youssouf M Mfopit, Lucien Rufener, John Graham-Brown, Vincent N Tanya, Martin Glenschek-Sieberth, Daniel Kulke, Benjamin L Makepeace   +17 more
doaj   +1 more source

Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells. [PDF]

PLoS ONE, 2012
Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans.
Matthew A Pettengill, Verissa W Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, David M Ojcius   +4 more
doaj   +1 more source

Serotonin Levels in the Serum of Persons with Onchocerciasis-Associated Epilepsy: A Case-Control Study

Pathogens, 2021
Onchocerciasis-associated epilepsy (OAE) is a devastating childhood disorder occurring in areas with high Onchocerca volvulus transmission. Despite epidemiological evidence showing the association between O.
Melissa Krizia Vieri, An Hotterbeekx, Michel Mandro, Joseph Nelson Siewe Fodjo, Alfred Dusabimana, Francoise Nyisi, Deby Mukendi, Joe Gwatsvaira, Samir Kumar-Singh, Robert Colebunders   +9 more
doaj   +1 more source

Ongoing Transmission of Onchocerca volvulus after 25 Years of Annual Ivermectin Mass Treatments in the Vina du Nord River Valley, in North Cameroon. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Recent reports of transmission interruption of Onchocerca volvulus, the causing agent of river blindness, in former endemic foci in the Americas, and more recently in West and East Africa, raise the question whether elimination of this ...
Albert Eisenbarth, Mbunkah Daniel Achukwi, Alfons Renz   +2 more
doaj   +1 more source

Surveillance for Onchocerciasis-Associated Epilepsy and OV16 IgG4 Testing of Children 6–10 Years Old Should Be Used to Identify Areas Where Onchocerciasis Elimination Programs Need Strengthening

Pathogens, 2022
To eliminate onchocerciasis-associated morbidity, it is important to identify areas where there is still high ongoing Onchocerca volvulus transmission.
Alfred Dusabimana, Joseph Nelson Siewe Fodjo, Michel Mandro Ndahura, Bruno P. Mmbando, Stephen Raimon Jada, Annelies Boven, Eric De Smet, Tony Ukety, Alfred K. Njamnshi, Anne Laudisoit, Steven Abrams, Robert Colebunders   +11 more
doaj   +1 more source

Nodding syndrome (NS) and Onchocerca Volvulus (OV) in Northern Uganda

The Pan African Medical Journal, 2017
Nodding Syndrome (NS) is a childhood neurological disorder characterized by atonic seizures, cognitive decline, school dropout, muscle weakness, thermal dysfunction, wasting and stunted growth.
David Kitara Lagoro, Denis Anywar Arony
doaj   +1 more source

Observações preliminares sobre a transmissão de oncocercose no rio Toototobi, Amazonas, Brasil [PDF]

Acta Amazonica, 1976
Resumo Em dezembro de 1975 os autores estudaram vários fatores que influenciam a transmissão de Onchocerca volvulus ao norte do Amazonas, no rio Toototobi. Observaram que a densidade de microfilarias de O.
A. J. Shelley, J. A. S. Nunes de Mello, R. G. O. Rees   +2 more
doaj   +1 more source

Atividades preliminares do programa de controle e tratamento da oncocercose no território Yanomâmi, Roraima, Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 1997
Após caracterização clínico-epidemiológica da oncocercose na região Yanomâmi, RR, Brasil, iniciada em 1993, a Fundação Nacional de Saúde (FNS) implementou um projeto piloto de controle e tratamento nos pólos de base de Tootobi e Balawaú.
Giovanini E. Coelho, João B.F. Vieira, Cláudio E. Oliveira, Deise A. Francisco, Luís R. Pinheiro   +4 more
doaj   +1 more source