Results 21 to 30 of about 26,229 (182)

Onchocerca volvulus is not detected in the cerebrospinal fluid of persons with onchocerciasis-associated epilepsy

International Journal of Infectious Diseases, 2020
Objectives: Epidemiological evidence links onchocerciasis with the development of epilepsy. The aim of this study was to detect Onchocerca volvulus microfilariae or its bacterial endosymbiont, Wolbachia, in the cerebrospinal fluid (CSF) of persons with ...
An Hotterbeekx, Stephen Raimon, Gasim Abd-Elfarag, Jane Y. Carter, Wilson Sebit, Abozer Suliman, Joseph Nelson Siewe Fodjo, Peter De Witte, Makoy Yibi Logora, Robert Colebunders, Samir Kumar-Singh   +10 more
doaj   +2 more sources

Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan [PDF]

Journal of Epidemiology and Global Health
Background Onchocerciasis, a neglected tropical disease (NTD) caused by Onchocerca volvulus, is hyperendemic in many parts of Africa, including South Sudan.
Chiara Trevisan, Amber Hadermann, Stephen Raimon Jada, Raphael A. Abong, Yak Yak Bol, Joseph N. Siewe Fodjo, Katja Polman, Robert Colebunders   +7 more
doaj   +2 more sources

An Antibody Biomarker Associated with Onchocerca volvulus Microfilariae Identified by Proteomic Analysis of Parasite Tissues Isolated from Paraffin Embedded O. volvulus Nodules by Laser Capture Microdissection. [PDF]

Am J Trop Med Hyg
Greene SE, Fischer K, Di Maggio LS, Rosa BA, Huang Y, Diekmann I, Cho BK, Lukowski J, Goo YA, Mitreva M, Opoku N, Weil GJ, Fischer PU.   +12 more
europepmc   +3 more sources

Virtual screening, MMGBSA, and molecular dynamics approaches for identification of natural products from South African biodiversity as potential Onchocerca volvulus pi-class glutathione S-transferase inhibitors [PDF]

Heliyon
We investigated 1012 molecules from natural products previously isolated from the South African biodiversity (SANCDB, https://sancdb.rubi.ru.ac.za/), for putative inhibition of Onchocerca volvulus pi-class glutathione S-transferase (Ov-GST2) by virtual ...
Mbah Bake Maraf, Bel Youssouf G. Mountessou, Tsahnang Fofack Hans Merlin, Pouyewo Ariane, Joëlle Nadia Nouping Fekoua, Takoua Bella Jean Yves, Tchuifon Tchuifon Donald Raoul, Auguste Abouem A Zintchem, Gouet Bebga, Ndassa Ibrahim Mbouombouo, Ponnadurai Ramasami   +10 more
doaj   +2 more sources

Histopathological evaluation of Onchocerca volvulus nodules by microscopy and by digital image analysis for the study of macrofilaricidal drug efficacy. [PDF]

Front Med (Lausanne), 2023
Fischer K, Dubben B, Debrah LB, Kuehlwein JM, Ricchiuto A, Debrah AY, Hoerauf A, Weil GJ, Fischer PU, Klarmann-Schulz U.   +9 more
europepmc   +2 more sources

Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum.

PLoS Neglected Tropical Diseases, 2018
BackgroundThe study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection.
John B Patton, Sasisekhar Bennuru, Mark L Eberhard, Jessica A Hess, April Torigian, Sara Lustigman, Thomas B Nutman, David Abraham   +7 more
doaj   +2 more sources

A Novel Biplex <i>Onchocerca volvulus</i> Rapid Diagnostic Test Evaluated Among 3- to 9-Year-Old Children in Maridi, South Sudan. [PDF]

Diagnostics (Basel)
Hadermann A, Jada SR, Lubbers C, Amaral LJ, Biamonte M, de Souza DK, Bol YY, Siewe Fodjo JN, Colebunders R.   +8 more
europepmc   +3 more sources

Optimized strategy for real-time qPCR detection of Onchocerca volvulus DNA in pooled Simulium sp. blackfly vectors. [PDF]

PLoS Negl Trop Dis, 2023
Doherty M, Grant JR, Pilotte N, Bennuru S, Fischer K, Fischer PU, Lustigman S, Nutman TB, Pfarr K, Hoerauf A, Unnasch TR, Hassan HK, Wanji S, Lammie PJ, Ottesen E, Mackenzie C, Williams SA.   +16 more
europepmc   +3 more sources

Real-Time Polymerase Chain Reaction Method for the Detection of Onchocerca volvulus in Post-Elimination Surveillance of Onchocerciasis in Ecuador. [PDF]

Am J Trop Med Hyg, 2023
Salazar E, Morales D, Febrer-Sendra B, Fernández-Soto P, López-Abán J, Quinatoa P, Guevara Á, Muro A.   +7 more
europepmc   +3 more sources

Assessing <i>Onchocerca volvulus</i> Intensity of Infection and Genetic Diversity Using Mitochondrial Genome Sequencing of Single Microfilariae Obtained before and after Ivermectin Treatment. [PDF]

Pathogens, 2023
Hedtke SM, Choi YJ, Kode A, Chalasani GC, Sirwani N, Jada SR, Hotterbeekx A, Mandro M, Siewe Fodjo JN, Amambo GN, Abong RA, Wanji S, Kuesel AC, Colebunders R, Mitreva M, Grant WN.   +15 more
europepmc   +3 more sources