Results 51 to 60 of about 13,454 (262)

Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study. [PDF]

open access: yes, 2002
BACKGROUND: The causes of metabolic syndrome (MS), which may be a precursor of coronary disease, are uncertain. We hypothesize that disturbances in neuroendocrine and cardiac autonomic activity (CAA) contribute to development of MS.
Andrew, R   +15 more
core   +1 more source

The Population Biology and Transmission Dynamics of Loa loa [PDF]

open access: yes, 2017
Endemic to Central Africa, loiasis – or African eye worm (caused by the filarial nematode Loa loa) – affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of public ...
Basáñez, M-G   +5 more
core   +1 more source

Tolerability, Safety, and Pharmacokinetics of Ivermectin After Nasal Application in Healthy Adult Subjects

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Nasal epithelium is the site of infection for SARS‐CoV2 viruses, with interactions of the viral spike protein with the ACE2 receptor of the host cell. Molecular docking studies have shown that ivermectin shields the spike protein and thereby prevents binding to ACE2.
Stefan Wissel   +5 more
wiley   +1 more source

The Functional Parasitic Worm Secretome: Mapping the Place of Onchocerca volvulus Excretory Secretory Products

open access: yesPathogens, 2020
Nematodes constitute a very successful phylum, especially in terms of parasitism. Inside their mammalian hosts, parasitic nematodes mainly dwell in the digestive tract (geohelminths) or in the vascular system (filariae). One of their main characteristics
Luc Vanhamme   +3 more
doaj   +1 more source

Factors affecting onchocerciasis transmission: Lessons for infection control [PDF]

open access: yes, 2017
Introduction: Onchocerca volvulus infects in excess of 15 million people. The vectors are Simulium blackflies, varieties of which differ in their ecologies, behaviour and vectorial abilities.
Cheke, Robert A.
core   +1 more source

Intestinal Parasites of Zoonotic Significance in Human and Domestic Animals in a Rural Setting in Nepal

open access: yesVeterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Intestinal parasites are shared among humans and domestic animals. Rural setting is critical to enhance parasite zoonosis in Nepal. ABSTRACT Intestinal parasitic (IP) species with zoonotic significance are major public health issues, mostly prevalent in developing countries, leading to high morbidity and mortality. The present study aimed to assess the
Prince Rai, Tirth Raj Ghimire
wiley   +1 more source

Potential value of triple drug therapy with ivermectin, diethylcarbamazine, and albendazole (IDA) to accelerate elimination of lymphatic filariasis and onchocerciasis in Africa [PDF]

open access: yes, 2017
<p>Background: Filarial nematodes are tissue-dwelling parasites that can be killed by Th2-driven immune effectors, but that have evolved to withstand immune attack and establish chronic infections by suppressing host immunity. As a consequence, the
Fischer, Peter U   +3 more
core   +14 more sources

Onchocerciasis control: biological research is still needed

open access: yesParasite, 2008
Achievements obtained by the onchocerciasis control programmes should not lead to a relaxation in the biological research on Onchocerca volvulus. Issues such as the Loa loa-related postivermectin serious adverse events, the uncertainties as to whether ...
Boussinesq M.
doaj   +1 more source

Unraveling cross-reactivity of anti-glycan IgG responses in filarial nematode infections

open access: yesFrontiers in Immunology, 2023
Parasitic nematodes responsible for filarial diseases cause chronic disablement in humans worldwide. Elimination programs have substantially reduced the rate of infection in certain areas, but limitations of current diagnostics for population ...
Laudine M. C. Petralia   +14 more
doaj   +1 more source

Efficacy of Immunostimulatory Adjuvants and Nano‐Adjuvants in Current SARS‐CoV‐2 Vaccines: A Comprehensive Review

open access: yesHealth Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims SARS‐CoV‐2 continues to pose global challenges, and current vaccines face limitations (variant escape, waning immunity). This review evaluates immunostimulatory adjuvants and nano‐adjuvants to enhance immune responses and optimize SARS‐CoV‐2 vaccine performance.
Peyman Kheirandish Zarandi   +5 more
wiley   +1 more source

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