Results 51 to 60 of about 31,479 (242)

The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]

, 2014
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf, Agwuh, Basáñez, Basáñez, Bosshardt, Cattamanchi, Chib, Churcher, de Andrade, Debrah, Duke, Duke, Gardon, Gelman, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Mand, Mark J. Taylor, Martin Walker, María-Gloria Basáñez, Norton, Osei-Atweneboana, Plaisier, Plaisier, Roberts, Sabine Specht, Specht, Tamarozzi, Taylor, Taylor, Taylor, Taylor, Taylor, Thomas S. Churcher, van Rie, Wanji, Wearing, World Health Organization, Xia   +43 more
core   +2 more sources

Preliminary evaluations of 3-dimensional human skin models for their ability to facilitate in vitro the long-term development of the debilitating obligatory human parasite Onchocerca volvulus

PLoS Neglected Tropical Diseases, 2020
Onchocerciasis also known as river blindness is a neglected tropical disease and the world's second-leading infectious cause of blindness in humans; it is caused by Onchocerca volvulus.
Christoph Malkmus, Shabnam Jawahar, Nancy Tricoche, S. Lustigman, J. Hansmann   +4 more
semanticscholar   +1 more source

Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]

, 2006
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Basáñez, M-G, Boussinesq, M, Clarke, P, Filipe, JAN, Gardon, J, Kamgno, J, Pion, SDS   +6 more
core   +1 more source

Small RNAs and extracellular vesicles in filarial nematodes: from nematode development to diagnostics [PDF]

, 2016
Parasitic nematodes have evolved sophisticated mechanisms to communicate with their hosts in order to survive and successfully establish an infection. The transfer of RNA within extracellular vesicles (EVs) has recently been described as a mechanism that
Babayan, S.A., Buck, A.H., Quintana, J.F.   +2 more
core   +2 more sources

What's in your next-generation sequence data? An exploration of unmapped DNA and RNA sequence reads from the bovine reference individual. [PDF]

, 2015
BackgroundNext-generation sequencing projects commonly commence by aligning reads to a reference genome assembly. While improvements in alignment algorithms and computational hardware have greatly enhanced the efficiency and accuracy of alignments, a ...
Alexander, Leeson J, Decker, Jared E, Kim, JaeWoo, Medrano, Juan F, Schnabel, Robert D, Schroeder, Steven G, Sonstegard, Tad S, Taylor, Jeremy F, Tizioto, Polyana C, Whitacre, Lynsey K   +9 more
core   +1 more source

Onchocerca volvulus

Definitions, 2020
This datasheet on Onchocerca volvulus covers Identity, Distribution, Hosts/Species Affected, Vectors & Intermediate Hosts.
A. Truant, Irma Palazzo, Byung-Kuk Suh, Francis Au   +3 more
semanticscholar   +1 more source

Stage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle [PDF]

, 2016
Despite 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected.
Adam, Altschul, Altschul, Anon, Argueta, Armstrong, Armstrong, Arumugam, Babayan, Bazzocchi, Bendtsen, Benjamini, Bennuru, Bennuru, Berry, Berry, Board, Boatin, Brattig, Brattig, Brophy, Bulman, Burbelo, Burchard, Burket, Butler, Chandrashekar, Chawade, Chhabra, Choi, Claros, Constam, Cooray, Crump, Darby, Darby, Desjardins, Duckert, Edgar, Edwards, Erttmann, Finn, Franceschini, Frank, Gallin, Gardon, GBD 2013 Mortality and Causes of Death Collaborators, Geary, Ghali, Ghedin, Ghosh, Gilbert, Globisch, Godel, Gomez-Escobar, Gopal, Gotenstein, Gottsch, Grainger, Gretes, Guan, Guiliano, Hansen, Henrichfreise, Hewitson, Hewitson, Hewitson, Hotez, Hunter, Ichishita, Joseph, Joza, Kanazawa, Klion, Ko, Koonin, Korten, Krogh, Larkin, Li, Li, Liebau, Liebau, Liebau, Liebau, Littler, Liu, Longo, Lu, Lundquist, Lustigman, Lustigman, Mackenzie, Makepeace, Marti, McGarry, McSorley, Melnikow, Meyer, Michalski, Morales-Hojas, Moreno, Moreno, Morris, Mossmann, Nana-Djeunga, Nfon, Nicholson, Nomura, Ohtsuki, Ohtsuki, Osei-Atweneboana, Page, Pant, Parra, Petersen, Plaisier, Quintana, Ranjan, Rew, Rogalski, Roth, Saitou, Schulz-Key, Schulz-Key, Scocchi, Sheehan, Silva, Sommer, Srivastava, Tamarozzi, Tanikawa, Taylor, Tchakouté, Ternent, Tew, Thompson, Tiwari, Trees, Vogel, Wahl, Waterhouse, Westermann, Wildenburg, Willenbucher, Wilson, Wisniewski, Wu, Wu, Xie, Xie, Yamaguchi, Yang, Yasuda, Zanetti, Zipfel   +155 more
core   +6 more sources

Atividades preliminares do programa de controle e tratamento da oncocercose no território Yanomâmi, Roraima, Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 1997
Após caracterização clínico-epidemiológica da oncocercose na região Yanomâmi, RR, Brasil, iniciada em 1993, a Fundação Nacional de Saúde (FNS) implementou um projeto piloto de controle e tratamento nos pólos de base de Tootobi e Balawaú.
Giovanini E. Coelho, João B.F. Vieira, Cláudio E. Oliveira, Deise A. Francisco, Luís R. Pinheiro   +4 more
doaj   +1 more source

Observações preliminares sobre a transmissão de oncocercose no rio Toototobi, Amazonas, Brasil [PDF]

Acta Amazonica, 1976
Resumo Em dezembro de 1975 os autores estudaram vários fatores que influenciam a transmissão de Onchocerca volvulus ao norte do Amazonas, no rio Toototobi. Observaram que a densidade de microfilarias de O.
A. J. Shelley, J. A. S. Nunes de Mello, R. G. O. Rees   +2 more
doaj   +1 more source

The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness [PDF]

, 2017
Background: Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca ...
Basáñez, Maria-Gloria, Boussinesq, Michel, Chesnais, Cédric, Chippaux, Jean-Philippe, Ernould, Jean-Christophe, Fang, Hanwei, Garcia, André, Gardon, J., Kamgno, Joseph, Pion, Sébastien, Ranque, Stephane, Tchatchueng-Mbougua, Jules Brice, Walker, Martin   +12 more
core   +2 more sources