Results 41 to 50 of about 18,093 (248)

Nodding syndrome research, lessons learned from the NSETHIO project

Cambridge Prisms: Global Mental Health, 2019
Background.Until recently, nodding syndrome (NS) was considered as a mysterious disease of unknown etiology. A link between onchocerciasis and epilepsy was suspected for a long time.
D. Geelhand de Merxem, J. N. Siewe Fodjo, S. Menon, A. Hotterbeekx, R. Colebunders   +4 more
doaj   +1 more source

Onchocerciasis Prevalence among Persons with Epilepsy in an Onchocerciasis Hypo-Endemic Area in the Democratic Republic of Congo: A Cross-Sectional Study

Pathogens, 2021
A high epilepsy prevalence has been reported in onchocerciasis meso- and hyper-endemic regions in sub-Saharan Africa, including in the Democratic Republic of Congo (DRC). We investigated whether onchocerciasis-associated epilepsy can also be suspected in
An Hotterbeekx, Kristien Verdonck, Deby Mukendi, Jean-Roger Lilo-Kalo, Pascal Lutumba, Marleen Boelaert, Liselotte Hardy, Barbara Barbé, Jan Jacobs, Emmanuel Bottieau, Robert Colebunders   +10 more
doaj   +1 more source

The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis Control: (1) priority areas for ivermectin treatment

Parasites & Vectors, 2014
Background The African Programme for Onchocerciasis Control (APOC) was created to control onchocerciasis as a public health problem in 20 African countries. Its main strategy is community directed treatment with ivermectin.
Mounkaila Noma, Honorat GM Zouré, Afework H Tekle, Peter AI Enyong, Bertram EB Nwoke, Jan HF Remme   +5 more
doaj   +1 more source

The World Health Organization 2030 goals for onchocerciasis: Insights and perspectives from mathematical modelling [version 1; peer review: 2 approved]

Gates Open Research, 2019
The World Health Organization (WHO) has embarked on a consultation process to refine the 2030 goals for priority neglected tropical diseases (NTDs), onchocerciasis among them.
NTD Modelling Consortium Onchocerciasis Group
doaj   +1 more source

Moxidectin: an oral treatment for human onchocerciasis

Expert Review of Anti-Infective Therapy, 2020
Introduction Moxidectin is a milbemycin endectocide recently approved for the treatment of human onchocerciasis. Onchocerciasis, earmarked for elimination of transmission, is a filarial infection endemic in Africa, Yemen, and the Amazonian focus ...
Philip Milton, Jonathan I D Hamley, M. Walker, M. Basáñez   +3 more
semanticscholar   +1 more source

Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch

Parasites & Vectors, 2015
Background Elimination of onchocerciasis in Africa is now regarded as an achievable goal in many areas. This makes monitoring changes in infection prevalence a key component of control programmes. Monitoring is currently based on determining the presence
K. Awadzi, Nicholas O. Opoku, Simon K. Attah, Janis K. Lazdins-Helds, Annette C. Kuesel   +4 more
doaj   +1 more source

The Role of the Maridi Dam in Causing an Onchocerciasis-Associated Epilepsy Epidemic in Maridi, South Sudan: An Epidemiological, Sociological, and Entomological Study

Pathogens, 2020
Background: An epilepsy prevalence of 4.4% was documented in onchocerciasis-endemic villages close to the Maridi River in South Sudan. We investigated the role of the Maridi dam in causing an onchocerciasis-associated epilepsy epidemic in these villages.
T. Lakwo, S. Raimon, M. Tionga, J. S. Fodjo, P. Alinda, Wilson Sebit, J. Carter, R. Colebunders   +7 more
semanticscholar   +1 more source

Elimination of onchocerciasis in Africa by 2025: an ambitious target requires ambitious interventions

Infectious Diseases of Poverty, 2019
To achieve the elimination of onchocerciasis transmission in all African countries will entail enormous challenges, as has been highlighted by the active discussion around onchocerciasis intervention strategies and evaluation procedures in this journal ...
Robert Colebunders, Wilma A. Stolk, Joseph Nelson Siewe Fodjo, Charles D. Mackenzie, Adrian Hopkins   +4 more
doaj   +1 more source

Persons with onchocerciasis-associated epilepsy and nodding seizures have a more severe form of epilepsy with more cognitive impairment and higher levels of Onchocerca volvulus infection.

Epileptic disorders, 2020
Following previous reports of very high epilepsy prevalence in the onchocerciasis-endemic villages in Maridi County, South Sudan, a study was conducted to investigate the association between the level of Onchocerca volvulus infection, epilepsy, and ...
G. Abd-Elfarag, J. Carter, S. Raimon, Wilson Sebit, Abozer Suliman, J. S. Fodjo, Peter Claver Olore, Kai Puok Biel, Morrish Ojok, M. Y. Logora, R. Colebunders   +10 more
semanticscholar   +1 more source

Evaluation of Lymphatic Filariasis and Onchocerciasis in Three Senegalese Districts Treated for Onchocerciasis with Ivermectin.

PLoS Neglected Tropical Diseases, 2016
In Africa, onchocerciasis and lymphatic filariasis (LF) are co-endemic in many areas. Current efforts to eliminate both diseases are through ivermectin-based mass drug administration (MDA).
Nana O Wilson, Alioune Badara Ly, Vitaliano A Cama, Paul T Cantey, Daniel Cohn, Lamine Diawara, Abdel Direny, Mawo Fall, Karla R Feeser, LeAnne M Fox, Achille Kabore, Amadou F Seck, Ngayo Sy, Daouda Ndiaye, Christine Dubray   +14 more
doaj   +1 more source