Results 11 to 20 of about 6,429 (163)
Presage of oncolytic virotherapy for oral cancer with herpes simplex virus
Japanese Dental Science Review, 2017 A virus is a pathogenic organism that causes a number of infectious diseases in humans. The oral cavity is the site at which viruses enter and are excreted from the human body.
Yoshiaki Yura
doaj +3 more sources
Growth, Purification, and Titration of Oncolytic Herpes Simplex Virus. [PDF]
J Vis Exp, 2021 Oncolytic viruses (OVs), such as the oncolytic herpes simplex virus (oHSV), are a rapidly growing treatment strategy in the field of cancer immunotherapy. OVs, including oHSV, selectively replicate in and kill cancer cells (sparing healthy/normal cells) while inducing anti-tumor immunity.
Nguyen HM +4 more
europepmc +3 more sources
Potent anti-tumor effects of receptor-retargeted syncytial oncolytic herpes simplex virus [PDF]
Molecular Therapy - Oncolytics, 2021 Shigeru Yanagi +2 more
exaly +2 more sources
Nectin-1 Expression Correlates with the Susceptibility of Malignant Melanoma to Oncolytic Herpes Simplex Virus In Vitro and In Vivo [PDF]
Cancers, 2021 Beatrice Schuler-Thurner +2 more
exaly +2 more sources
Advances in antitumour therapy with oncolytic herpes simplex virus combinations. [PDF]
Discov OncolAbstractOncolytic Virus (OVs) is an emerging approach to tumour immunity that allows the use of natural or genetically modified viruses to specifically infect and lyse tumour cells without damaging normal cells. Oncolytic herpes simplex virus (oHSV) is one of the more widely researched and applied OVs in the field of oncology, which can directly kill ...
Qi X.
europepmc +4 more sources
Frontiers in Cellular and Infection Microbiology, 2023 Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis virus (VSV), parvovirus, mammalian reovirus (MRV), human adenovirus ...
Yi-Ying Wu +9 more
doaj +1 more source
Oncolytic herpes simplex virus vectors for cancer virotherapy [PDF]
Cancer Gene Therapy, 2002 Oncolytic herpes simplex virus type 1 (HSV-1) vectors are emerging as an effective and powerful therapeutic approach for cancer. Replication-competent HSV-1 vectors with mutations in genes that affect viral replication, neuropathogenicity, and immune evasiveness have been developed and tested for their safety and efficacy in a variety of mouse models ...
Susan, Varghese, Samuel D, Rabkin
openaire +2 more sources
Nature Communications, 2021 Oncolytic herpes simplex virus-1 lyses cancer cells while increases their immunogenicity. Blocking the CD47 “don’t eat me” signal on cancer cells promotes their phagocytosis by macrophages.
Bo Xu +12 more
doaj +1 more source
Molecular Therapy: Oncolytics, 2023 Oncolytic viruses, modified for tumor-restricted infection, are a promising cancer immunotherapeutic, yet much remains to be understood about factors driving their activity and outcome in the tumor microenvironment.
Jack Hedberg +17 more
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Oncolytic herpes simplex virus infects myeloma cells <i>in vitro</i> and <i>in vivo</i>. [PDF]
Mol Ther Oncolytics, 2021 Because most patients with multiple myeloma (MM) develop resistance to current regimens, novel approaches are needed. Genetically modified, replication-competent oncolytic viruses exhibit high tropism for tumor cells regardless of cancer stage and prior treatment.
Ghose J +17 more
europepmc +5 more sources