A mathematical model of oncolytic virotherapy with time delay
Mathematical Biosciences and Engineering, 2019 Oncolytic virotherapy is an emerging treatment modality which uses replication-competent viruses to destroy cancers without causing harm to normal tissues.
Zizi Wang, Zhiming Guo, Hal Smith
doaj +1 more source
922. Engineering of Oncolytic Adenoviruses for Targeted and Efficient Virotherapy of Malignant Melanoma [PDF]
, 2003 openalex +1 more source
Molecular Therapy: Oncolytics, 2019 As a clinical setting in which novel treatment options are urgently needed, hepatocellular carcinoma (HCC) exhibits intriguing opportunities for oncolytic virotherapy.
Yong Luo +11 more
doaj
Current landscape and perspective of oncolytic viruses and their combination therapies
Translational Oncology, 2022 Oncolytic virotherapy has become an important strategy in cancer immunotherapy. Oncolytic virus (OV) can reshape the tumor microenvironment (TME) through its replication-mediated oncolysis and transgene-produced anticancer effect, inducing an antitumor ...
Yinghan Su, Changqing Su, Lunxiu Qin
doaj
77. Production and Purification of Measles Virus for Oncolytic Virotherapy Clinical Trials [PDF]
, 2004 Dhanalakshmi Chinnasamy +5 more
openalex +1 more source
327. Retargetable Oncolytic Measles Viruses for Cancer Virotherapy [PDF]
, 2004 Takafumi Nakamura +3 more
openalex +1 more source
A phenotype-structured mathematical model for the influence of hypoxia on oncolytic virotherapy [PDF]
arXivThe effectiveness of oncolytic virotherapy is significantly affected by several elements of the tumour microenvironment, which reduce the ability of the virus to infect cancer cells. In this work, we focus on the influence of hypoxia on this therapy and develop a novel continuous mathematical model that considers both the spatial and epigenetic ...
arxiv
949. Oncolytic Autonomous Parvovirus (rH1-yCD) Targeting with P4/Carcinoembryonic Antigen Chimeric Promoter for Virotherapy of Pancreatic Cancer [PDF]
, 2006 Soukaina Réjiba +2 more
openalex +1 more source
Oncolytic virotherapy for ovarian carcinomatosis using a replication-selective vaccinia virus armed with a yeast cytosine deaminase gene [PDF]
, 2007 Sricharan Chalikonda +10 more
openalex +1 more source
Oncolytic virotherapy – Forging its place in the immunomodulatory paradigm for Multiple Myeloma
Cancer Treatment and Research Communications, 2021 The treatment focus for multiple myeloma (MM) has recently pivoted towards immune modulating strategies, with T-cell redirection therapies currently at the forefront of drug development.
Joselle Cook, MD +4 more
doaj