Mathematical modeling of tumor therapy with oncolytic viruses: Effects of parametric heterogeneity on cell dynamics [PDF]
arXiv, 2006 One of the mechanisms that ensure cancer robustness is tumor heterogeneity, and its effects on tumor cells dynamics have to be taken into account when studying cancer progression. There is no unifying theoretical framework in mathematical modeling of carcinogenesis that would account for parametric heterogeneity.
arxiv
Effect of Oncolytic Virotherapy With Herpes Simplex Virus Mutants on Human Oral Squamous Cell Carcinoma Cells [PDF]
, 2007 Fumi Ogawa
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Molecular Therapy: Oncolytics, 2023 Tumor antigen-driven responses to weakly immunogenic self-antigens and neoantigens directly affect treatment efficacy following immunotherapy. Using orthotopically grown SV40 T antigen+ ovarian carcinoma in antigen-naive wild-type or TgMISIIR-TAg-Low ...
Anna Mistarz +11 more
doaj
763. Mutual Sensitization with Telomerase-Specific Oncolytic Virotherapy and Ionizing Radiation in Cytotoxic Activity Against Human Cancer [PDF]
, 2007 openalex +1 more source
TGF-β Inhibition Improves Oncolytic Herpes Viroimmunotherapy in Murine Models of Rhabdomyosarcoma
Molecular Therapy: Oncolytics, 2017 Oncolytic viruses are an emerging class of cancer therapeutics that couple cytotoxicity with the induction of an anti-tumor immune response. Host-virus interactions are complex and modulated by a tumor microenvironment whose immunosuppressive activities ...
Brian Hutzen +8 more
doaj
Fighting Fire With Fire: Effects of Oncolytic Virotherapy on Underlying Viral Hepatitis in Hepatocellular Carcinoma [PDF]
, 2008 Tony Reid
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Population models with singular equilibrium [PDF]
arXiv, 2006 A class of models of biological population and communities with a singular equilibrium at the origin is analyzed; it is shown that these models can possess a dynamical regime of deterministic extinction, which is crucially important from the biological standpoint.
arxiv
Molecular Therapy: Oncolytics, 2018 Ewing sarcoma is a highly aggressive cancer that promotes the infiltration and activation of pro-tumor M2-like macrophages. Oncolytic virotherapy that selectively infects and destroys cancer cells is a promising option for treating Ewing sarcoma.
Nicholas L. Denton +11 more
doaj
Preclinical evaluation of synergistic effect of telomerase-specific oncolytic virotherapy and gemcitabine for human lung cancer [PDF]
, 2009 Dong Liu +8 more
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Interim results of a clinical trial using oncolytic virotherapy in Kaposi's sarcoma-associated herpesvirus (KSHV) associated-Multicentric Castleman's Disease (MCD) [PDF]
, 2009 Robert Yarchoan +11 more
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