Results 21 to 30 of about 1,058,979 (232)
The XVIII International Parvovirus Workshop Rimini, Italy, 14–17 June 2022
Viruses, 2023 The XVIII International Parvovirus Workshop took place in Rimini, Italy, from 14 to 17 June 2022 as an on-site event, continuing the series of meetings started in 1985 and continuously held every two years.
Giorgio Gallinella, Antonio Marchini
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Development of a WNT-selective oncolytic adenovirus for imaging the therapy of colorectal cancers. [PDF]
, 2008 PhDIntroduction: The concept of oncolytic adenoviruses has been validated in preclinical studies but clinical trials have demonstrated that the virus spread remains limited and the virus fails to infect all cancer cells in a tumour.
Peerlinck, Inge D. L.
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Assessment and development of adenovirus type 11 for cancer therapy [PDF]
, 2010 PhDThe efficacy of oncolytic virotherapy is influenced by the interactions between the tumour, virus and host immunity. The first generation of oncolytic adenoviruses, based on serotype 5 (Ad5), has achieved limited success in clinical trials.
Wong, Han Hsi
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Oncolytic H-1 Parvovirus Enters Cancer Cells through Clathrin-Mediated Endocytosis
Viruses, 2020 H-1 protoparvovirus (H-1PV) is a self-propagating virus that is non-pathogenic in humans and has oncolytic and oncosuppressive activities. H-1PV is the first member of the Parvoviridae family to undergo clinical testing as an anticancer agent.
Tiago Ferreira +5 more
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Molecular Therapy: Oncolytics, 2021 The oncolytic effect of virotherapy derives from the intrinsic capability of the applied virus in selectively infecting and killing tumor cells. Although oncolytic viruses of various constructions have been shown to efficiently infect and kill tumor ...
Divya Ravirala +3 more
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Recent advances in oncolytic virus therapy for hepatocellular carcinoma
Frontiers in Oncology, 2023 Hepatocellular carcinoma (HCC) is a highly refractory cancer and the fourth leading cause of cancer-related mortality worldwide. Despite the development of a detailed treatment strategy for HCC, the survival rate remains unsatisfactory.
Licheng Zhu +14 more
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Immune mediated and direct killing of colorectal cancer by reovirus [PDF]
, 2012 Colorectal cancer remains the second most prevalent cancer in the world. Novel treatment strategies are necessary, especially for the treatment of metastatic disease.
Adair, Robert Allan
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Suppression of CCDC6 sensitizes tumor to oncolytic virus M1
Neoplasia: An International Journal for Oncology Research, 2021 Oncolytic virus is an effective therapeutic strategy for cancer treatment, which exploits natural or manipulated viruses to selectively target and kill cancer cells.
Ying Liu +12 more
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Oncolytic Effects of a Novel Influenza A Virus Expressing Interleukin-15 from the NS Reading Frame [PDF]
, 2012 Oncolytic influenza A viruses with deleted NS1 gene (delNS1) replicate selectively in tumour cells with defective interferon response and/or activated Ras/Raf/MEK/ERK signalling pathway.
Martin Michaelis +32 more
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Oncolytic Viruses: Immunotherapy Drugs for Gastrointestinal Malignant Tumors
Frontiers in Cellular and Infection Microbiology, 2022 Oncolytic virus therapy has advanced rapidly in recent years. Natural or transgenic viruses can target tumor cells and inhibit tumor growth and metastasis in various ways without interfering with normal cell and tissue function.
Qingbo Li +9 more
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