Results 31 to 40 of about 23,985 (238)

Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect [PDF]

, 2017
: With the advancement of a growing number of oncolytic viruses (OVs) to clinical development, drug delivery is becoming an important barrier to overcome for optimal therapeutic benefits.

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Measles virus causes immunogenic cell death in human melanoma [PDF]

, 2011
NoOncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Russell, S, Selby, P., Hadac, E., Donnelly, Oliver G, Jennings, V., Errington-Mais, F., Melcher, Alan A, Hadac, Elizabeth, Bond, J, Melcher, A.A., Bond, Jacquelyn, Selby, P, Bond, J., Peach, H., Vile, Richard, Steele, L., Vile, R., Hadac, E, Donnelly, O.G., Russell, Stephen, Harrington, K.J., Harrington, K, Peach, Howard, Steele, Lynette, Melcher, AA, Errington-Mais, Fiona, Harrington, Kevin, Russell, S., Phillips, Roger M., Pandha, H.S., Selby, Peter, Errington-Mais, F, Jennings, V, Scott, K, Phillips, RM, Phillips, Roger M, Scott, K., Pandha, Hardev, Vile, R, Jennings, Victoria, Steele, L, Pandha, H, Scott, Karen, Donnelly, OG, Peach, H   +44 more
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Key parameters of measles virus production for oncolytic virotherapy [PDF]

, 2012
Attenuated measles virus has revealed selective tumor cell killing and is currently tested in clinical trials for the therapy of cancer patients. The amount of infectious particles per dose needed for oncolytic therapy can be more than a million times ...
Salzig, Denise, Mühlebach, Michael D., Salzig, D., Pörtner, Ralf, Cichutek, K., Czermak, Peter, Mühlebach, M. D., Weiss, Katja, Cichutek, Klaus, Pörtner, R., Weiss, K.   +10 more
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Enhanced Therapeutic Efficacy of a Novel Oncolytic Herpes Simplex Virus Type 2 Encoding an Antibody Against Programmed Cell Death 1

Molecular Therapy: Oncolytics, 2019
The efficacy of immune checkpoint blockade therapy against immunologically “cold” tumors can be enhanced by applying the checkpoint inhibitors in combination with oncolytic viruses.
Yujie Zhu, Xiao Hu, Lin Feng, Zhenrong Yang, Lulin Zhou, Xinchun Duan, Shujun Cheng, Wen Zhang, Binlei Liu, Kaitai Zhang   +9 more
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Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1

Journal for ImmunoTherapy of Cancer, 2023
Background Transgenes deliver therapeutic payloads to improve oncolytic virus immunotherapy. Transgenes encoded within oncolytic viruses are designed to be highly transcribed, but protein synthesis is often negatively affected by viral infection ...
Huy-Dung Hoang, Aida Said, Nasana Vaidya, Victoria H Gilchrist, Kyle Malone, Usha Kabilan, Serena Topshee, Xiao Xiang, An-Dao Yang, David Olagnier, Karen Mossman, Shawn T Beug, Seyed Mehdi Jafarnejad, Samuel T Workenhe, Tyson E Graber, Tommy Alain   +15 more
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The Oncolytic Virus in Cancer Diagnosis and Treatment

Frontiers in Oncology, 2020
Cancer has always been an enormous threat to human health and survival. Surgery, radiotherapy, and chemotherapy could improve the survival of cancer patients, but most patients with advanced cancer usually have a poor survival or could not afford the ...
Guo-dong Cao, Xiao-bo He, Qiang Sun, Sihan Chen, Ke Wan, Xin Xu, Xudong Feng, Peng-ping Li, Bo Chen, Mao-ming Xiong   +9 more
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Development and application of oncolytic viruses as the nemesis of tumor cells

Frontiers in Microbiology, 2023
Viruses and tumors are two pathologies that negatively impact human health, but what occurs when a virus encounters a tumor? A global consensus among cancer patients suggests that surgical resection, chemotherapy, radiotherapy, and other methods are the ...
Xiao Zhu, Xiao Zhu, Xiao Zhu, Chenyang Fan, Zhuolong Xiong, Mingwei Chen, Zesong Li, Tao Tao, Xiuqing Liu   +8 more
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Research progress of oncolytic virus combined with PD-1/PD-L1 inhibitors [PDF]

Jichu yixue yu linchuang, 2022
Oncolytic viruses are often used in combination with immune checkpoint inhibitors represented in two ways by programmed cell death 1/programmed cell death-Ligand 1 (PD-1/PD-L1).
GAN Zi-ying, TANG Hui
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New frontiers in oncolytic viruses: optimizing and selecting for virus strains with improved efficacy [PDF]

, 2018
Kenneth Lundstrom PanTherapeutics, Lutry, Switzerland Abstract: Oncolytic viruses have demonstrated selective replication and killing of tumor cells.
Lundstrom K, Kenneth Lundstrom
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Pre-made Oncolytic Vaccinia Virus [PDF]

, 2023
 Among the several types of anti-cancer treatments, Pre-made Oncolytic Vaccinia Virus targets and kills tumor cells only, sparing healthy cells. 
candy swift (14858320)
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