The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay +7 more
wiley +1 more source
Leptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemma [PDF]
, 2015 The prevalence of global obesity is increasing. Obesity is associated with general cancer-related morbidity and mortality and is a known risk factor for development of specific cancers.
Alfraidi, Albandri +5 more
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Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid
Advanced Functional Materials, Volume 36, Issue 7, 22 January 2026.In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang +16 more
wiley +1 more source
Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]
, 1999 Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Prelle, Katja +4 more
core +1 more source
Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses [PDF]
, 2022 Piotr Topolewski +6 more
openalex +1 more source
Borate‐Ion‐Stimulated Macrophages Promote Osteogenic Differentiation of Mesenchymal Stem Cells
Advanced Healthcare Materials, Volume 15, Issue 2, 14 January 2026.The immune responses of mouse macrophages stimulated by borate ions promote the osteogenic differentiation and mineralization of mouse bone marrow–derived mesenchymal stem cells in an ion‐dose‐dependent manner by providing cytokines, including BMP‐2.
Kazumasa Ikedo +4 more
wiley +1 more source
Бюллетень сибирской медициныAim. To determine concentrations and identify the relationship of biomarkers (endocan / cell-specific molecule-1, fatty acid binding protein 4 (FABP 4), placental growth factor (PlGF), oncostatin M), with parameters of collageninduced platelet ...
O. A. Trubacheva +6 more
doaj +1 more source
Indicators of endocrine function of muscle and fat tissue in athletes participating in martial arts
Спортивная медицина: наука и практикаPurpose of the study: the aim of that study was an investigation of the level of adipokines, myokines and growth factors in the blood of athletes involved in acyclic sports — martial arts.Materials and methods: we have investigated 15 male athletes aged ...
A. V. Shestopalov +7 more
doaj +1 more source
Transcriptome adaptation of the bovine mammary gland to diets rich in unsaturated fatty acids shows greater impact of linseed oil over safflower oil on gene expression and metabolic pathways [PDF]
, 2016 Differentially expressed genes implicated in apoptosis of cows in LSO treatment as compared to the same cows on the control diet. Expression direction of several genes predicted to decrease apoptosis.
Adolf A. Ammah +6 more
core +14 more sources
Combined Use of Fecal Biomarkers in Inflammatory Bowel Diseases: Oncostatin M and Calprotectin
Journal of Inflammation Research, 2021 Ying Cao,1,* Yibei Dai,1,* Lingyu Zhang,1 Danhua Wang,1 Wen Hu,2 Qiao Yu,3 Xuchu Wang,1 Pan Yu,1 Weiwei Liu,1 Ying Ping,1 Tao Sun,1 Yiwen Sang,1 Zhenping Liu,4 Yan Chen,3 Zhihua Tao1 1Department of Laboratory Medicine, Zhejiang University School ...
Cao Y +14 more
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