Results 31 to 40 of about 20,861 (258)

The Enigmatic Cytokine Oncostatin M and Roles in Disease [PDF]

ISRN Inflammation, 2013
Carl D. Richards
openalex   +3 more sources

Oncostatin-M functionalized cryogel microspheres for promoting diabetic bone defects regeneration. [PDF]

J Orthop Translat
Song R, Yuan X, Wan Z, Zhang L, Rao F, Zhao Y, Yuan Z.   +6 more
europepmc   +2 more sources

“Comparative study of serum and synovial fluid Oncostatin M level in rheumatoid arthritis and osteoarthritis patients”

Journal of Radiation Research and Applied Sciences, 2022
Background: Rheumatoid arthritis (RA) remains a long-standing inflammatory syndrome where the joint synovial membrane is inflamed, with subsequent joint deformation. Osteoarthritis (OA) is considered to be a progressive destruction of articular cartilage
Iman H. Bassyouni, Dina F. Elessawi, Mohamed S. Tawfik, Neveen M. Nosseir   +3 more
doaj   +1 more source

Oncostatin M blockade attenuates colitis [PDF]

Nature Reviews Drug Discovery, 2017
openaire   +3 more sources

Oncostatin M is a regulator of fibroblast growth factor 23 (FGF23) in UMR106 osteoblast-like cells

Scientific Reports, 2023
Renal phosphate and vitamin D metabolism is under the control of fibroblast growth factor 23 (FGF23), an endocrine and paracrine factor predominantly produced in bone. FGF23 formation is stimulated by active vitamin D, or parathyroid hormone (PTH), which
Sina Münz, Martina Feger, Michael Föller   +2 more
doaj   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis [PDF]

, 2012
Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis.
Anderson, G.P., Bozinovski, S., Ernst, M.R., Jarnicki, A.G., Jones, J., Knight, D.A., Lau, H.L., Laurent, G.J., McAnulty, R.J., McKenzie, B.S., Mutsaers, S.E., O'Donoghue, R.J.J., Prêle, C.M., Richards, C.D., Rose-John, S., Stumbles, P.A., Thiem, S., Vlahos, R., Wang, B., Zhu, H.J.   +19 more
core   +4 more sources

Macrophage-derived oncostatin M repairs the lung epithelial barrier during inflammatory damage. [PDF]

Science
Hoagland DA, Rodríguez-Morales P, Mann AO, Baez Vazquez AY, Yu S, Lai A, Kane H, Dang SM, Lin Y, Thorens L, Begum S, Castro MA, Pope SD, Lim J, Li S, Zhang X, Li MO, Kim CF, Jackson R, Medzhitov R, Franklin RA.   +20 more
europepmc   +2 more sources

The clinical relevance of OSM in inflammatory diseases: a comprehensive review

Frontiers in Immunology, 2023
Oncostatin M (OSM) is a pleiotropic cytokine involved in a variety of inflammatory responses such as wound healing, liver regeneration, and bone remodeling. As a member of the interleukin-6 (IL-6) family of cytokines, OSM binds the shared receptor gp130,
Cody L. Wolf, Clyde Pruett, Darren Lighter, Cheryl L. Jorcyk, Cheryl L. Jorcyk   +4 more
doaj   +1 more source

Association between Oncostatin M Expression and Inflammatory Phenotype in Experimental Arthritis Models and Osteoarthritis Patients

Cells, 2021
Pro-inflammatory cytokines are considered to play a major role in osteoarthritis (OA), yet so far, the specific cytokines involved in the pathology of OA have not been identified. Oncostatin M (OSM) is a cytokine from the interleukin 6 (IL-6) family that
Joao Pedro Garcia, Lizette Utomo, Imke Rudnik-Jansen, Jie Du, Nicolaas P.A. Zuithoff, Anita Krouwels, Gerjo J.V.M. van Osch, Laura B. Creemers   +7 more
doaj   +1 more source