Results 61 to 70 of about 21,326 (236)
Cardiac oxidative stress and inflammatory cytokines response after myocardial infarction [PDF]
, 2015 Oxidative stress in heart failure or during ischemia/reperfusion occurs as a result of the excessive generation or accumulation of free radicals or their oxidation products.
Cerretani D. +6 more
core +1 more source
Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis
Arthritis &Rheumatology, Accepted Article.Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm +2 more
wiley +1 more source
Oncostatin M and its role in fibrosis [PDF]
Connective Tissue Research, 2018 Oncostain M, a member of the IL-6 family of cytokines, is produced by immune cells in response to infections and tissue injury. OSM has a broad, often context-dependent effect on various cellular processes including differentiation, hematopoiesis, cell proliferation, and cell survival.
Lukasz, Stawski, Maria, Trojanowska
openaire +2 more sources
Journal of International Medical Research, 2020 Objective This study aimed to explore whether initial hyperbaric oxygen treatment affects the stemness of glioma stem cells using an in vivo basal ganglia glioma model. Methods A basal ganglia glioma rat model was established. Rats were exposed to normal
Kun Song +5 more
doaj +1 more source
Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response. [PDF]
, 2013 BackgroundTraumatic brain injury (TBI) results in irreversible damage at the site of impact and initiates cellular and molecular processes that lead to secondary neural injury in the surrounding tissue.
Ford, Byron D +5 more
core +2 more sources
Oncostatin M Confers Neuroprotection against Ischemic Stroke [PDF]
Journal of Neuroscience, 2015 Cell-surface receptors provide potential targets for the translation of bench-side findings into therapeutic strategies; however, this approach for the treatment of stroke is disappointing, at least partially due to an incomplete understanding of the targeted factors.
Sen, Guo +11 more
openaire +2 more sources
Frontiers in Molecular Biosciences, 2020 Therapeutics targeting cytokines such as the oncostatin M (OSM)-mediated inflammation represent a potential strategy for the treatment of inflammatory bowel disease (IBD). Despite the investigation of the specific role of the interactions between OSM and
Qingqing Du, Yan Qian, Weiwei Xue
doaj +1 more source
P282 High plasma oncostatin-M predicts non-response to tumour necrosis factor-alpha antagonists in inflammatory bowel disease [PDF]
, 2021 Angela Guo +8 more
openalex +1 more source
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objectives Eosinophilic esophagitis (EoE) is characterized by eosinophilic inflammation and epithelial remodeling. However, current biomarkers focus predominantly on eosinophilia, overlooking basal cell hyperplasia (BCH), a histologic feature that may persist despite treatment.
Adi Eindor‐Abarbanel +7 more
wiley +1 more source
Expression of nephronectin is inhibited by oncostatin M via both JAK/STAT and MAPK pathways
FEBS Open Bio, 2015 Nephronectin (Npnt), also called POEM, is an extracellular matrix protein considered to play critical roles as an adhesion molecule in the development and functions of various tissues, such as the kidneys, liver, and bones.
Tamaki Kurosawa +12 more
doaj +1 more source