Results 51 to 60 of about 20,326,064 (257)
One-Carbon Metabolism Nutrients, Genetic Variation, and Diabetes Mellitus [PDF]
Diabetes & Metabolism JournalDiabetes mellitus (DM) affects about 9.3% of the population globally. Hyperhomocysteinemia (HHcy) has been implicated in the pathogenesis of DM, owing to its promotion of oxidative stress, β-cell dysfunction, and insulin resistance.
Jie Zhu +4 more
doaj +1 more source
Chromium induced neurotoxicity by altering metabolism in zebrafish larvae
Ecotoxicology and Environmental Safety, 2021 Background: Recently, both trivalent chromium Cr (III) and hexavalent chromium Cr (VI) have been reported to produce neurotoxicity. However, the underlying mechanisms of the neurotoxicity caused by different chemical valence of chromium remain unclear ...
Yawen Xu +6 more
doaj +1 more source
Correction to: Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in Mexico [PDF]
, 2019 Correction to: "Maternal one carbon metabolism and arsenic methylation in a pregnancy cohort in ...
Gamble, Mary V. +8 more
core +1 more source
Metabolomics analysis reveals dysregulation in one carbon metabolism in Friedreich Ataxia [PDF]
, 2022 Friedreich Ataxia (FA) is a rare and often fatal autosomal recessive disease in which a mitochondrial protein, frataxin (FXN), is severely reduced in all tissues. With loss of FXN, mitochondrial metabolism is severely disrupted.
Payne, R. Mark +5 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
One carbon metabolism in anaerobic bacteria: Regulation of carbon and electron flow during organic acid production [PDF]
, 1992 This reporting period, progress is reported on the following: metabolic pathway of solvent production in B. methylotrophicum; the biochemical mechanism for metabolic regulation of the succinate fermentation; models to understand the physiobiochemical ...
Jain, M. K., Zeikus, J. G.
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Cancer MedicineBackground RT4 bladder cancer cell line, derived from a nonmuscle‐invasive low‐grade subtype, is one of the few neoplastic cell lineages that maintain high expression of the candidate tumor suppressor ALDH1L1.
Halle M. Meyers +9 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Nature Communications, 2023 Flavin containing monooxygenase 2 (FMO-2) is known to increase lifespan under dietary restriction through incompletely understood mechanisms. Here the authors report that FMO-2 modifies tryptophan and methionine metabolic pathways to enhance stress ...
Hyo Sub Choi +14 more
doaj +1 more source