Results 21 to 30 of about 341,624 (160)
The Impact of One Carbon Metabolism on Histone Methylation
Frontiers in Genetics, 2019 The effect of one carbon metabolism on DNA methylation has been well described, bridging nutrition, metabolism, and epigenetics. This modification is mediated by the metabolite S-adenosyl methionine (SAM), which is also the methyl-donating substrate of ...
Magdalini Serefidou +2 more
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The Antioxidant Role of One-Carbon Metabolism on Stroke
Antioxidants, 2020 One-carbon (1C) metabolism is a metabolic network that is centered on folate, a B vitamin; it integrates nutritional signals with biosynthesis, redox homeostasis, and epigenetics.
Kassidy Burgess +5 more
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Abnormalities in one-carbon metabolism in young patients with psychosis
Frontiers in Psychiatry, 2023 IntroductionFolates, the main actors in one-carbon (C1) metabolism, are involved in synthesising monoamines and maintaining genomic stability. Previous studies support the association between C1 metabolism and schizophrenia.
Ariel Frajerman +13 more
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Cancer & Metabolism, 2017 Background Folate-dependent one-carbon metabolism provides one-carbon units for several biological processes. This pathway is highly compartmentalized in eukaryotes, with the mitochondrial pathway producing formate for use in cytoplasmic processes.
Minhye Shin +2 more
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One-Carbon Metabolism: Pulling the Strings behind Aging and Neurodegeneration
Cells, 2022 One-carbon metabolism (OCM) is a network of biochemical reactions delivering one-carbon units to various biosynthetic pathways. The folate cycle and methionine cycle are the two key modules of this network that regulate purine and thymidine synthesis ...
Eirini Lionaki +2 more
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Sex differences in hepatic one-carbon metabolism [PDF]
BMC Systems Biology, 2018 There are large differences between men and women of child-bearing age in the expression level of 5 key enzymes in one-carbon metabolism almost certainly caused by the sex hormones. These male-female differences in one-carbon metabolism are greatly accentuated during pregnancy.
Farrah Sadre-Marandi +3 more
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One-carbon metabolism in psychiatric illness [PDF]
Nutrition Research Reviews, 2006 The cost of psychiatric illness to the UK economy was recently estimated at £77 billion annually. Despite years of research no firm aetiological explanation exists, and with no physiological or biochemical markers diagnosis is made entirely on a behavioural basis. All current pharmacological therapies are associated with serious long-term side effects.
openaire +2 more sources
IDH3α regulates one-carbon metabolism in glioblastoma [PDF]
Science Advances, 2019 IDH3α promotes glioblastoma progression and links mitochondrial metabolism to cSHMT-controlled one-carbon metabolism.
Jasmine L. May +13 more
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Targeted Proteomics for Monitoring One-Carbon Metabolism in Liver Diseases
Metabolites, 2022 Liver diseases cause approximately 2 million deaths per year worldwide and had an increasing incidence during the last decade. Risk factors for liver diseases include alcohol consumption, obesity, diabetes, the intake of hepatotoxic substances like ...
Laura Guerrero +2 more
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Clinical Nutrition Experimental, 2016 Background: Homeostatic mechanisms that regulate long-term circulating concentrations of choline and one-carbon metabolites can obscure the relationship between diet and nutritional response.
Clara E. Cho +5 more
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