Results 71 to 80 of about 183,998 (331)
Bootstrapping ontology alignment methods with APFEL [PDF]
Special interest tracks and posters of the 14th international conference on World Wide Web - WWW '05, 2005 Ontology alignment is a prerequisite in order to allow for interoperation between different ontologies and many alignment strategies have been proposed to facilitate the alignment task by (semi-)automatic means. Due to the complexity of the alignment task, manually defined methods for (semi-)automatic alignment rarely constitute an optimal ...
Ehrig, M., Staab, S., Sure, Y.
openaire +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Bayesian Evaluation and Comparison of Ontology Alignment Systems
IEEE Access, 2019 Ontology alignment systems are evaluated by various performance scores, which are usually computed by a ratio related directly to the frequency of the true positives.
Majid Mohammadi
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Meaning Management: A Framework for Leadership Ontology [PDF]
, 2019 Leadership is a multifaceted and complex subject of research and demands a sound ontological stance that guides studies for the development of more integrative leadership theories.
Oral, Muhittin
core +1 more source
, 1939 With the proliferation of ontologies and their use in semantically-enabled applications, the issue of finding and repairing defects in ontologies has become increasingly important. Current work mostly targets debugging semantic defects in ontologies.
Lambrix, Patrick, Liu, Qiang
core +3 more sources
An API for Ontology Alignment [PDF]
, 2004 Ontologies are seen as the solution to data heterogeneity on the web. However, the available ontologies are themselves source of heterogeneity. This can be overcome by aligning ontologies, or finding the correspondence between their components. These alignments deserve to be treated as objects: they can be referenced on the web as such, be completed by
openaire +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Alignment of vaccine codes using an ontology of vaccine descriptions
Journal of Biomedical Semantics, 2022 Background Vaccine information in European electronic health record (EHR) databases is represented using various clinical and database-specific coding systems and drug vocabularies. The lack of harmonization constitutes a challenge in reusing EHR data in
Benedikt FH Becker +3 more
doaj +1 more source