Results 61 to 70 of about 48,631 (292)
Epigenetic regulation of germ cell and early embryonic development by Polycomb group proteins [PDF]
, 2011 Mammalian development begins at fertilization, when two highly specialized gametes, sperm and oocyte fuse to form a zygote. It is well established that early development of the embryo is driven by factors that are inherited from the oocyte.
Pósfai, Eszter
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Time-lapse confocal imaging-induced calcium ion discharge from the cumulus-oocyte complex at the time of cattle oocyte activation [PDF]
, 2020 Oocyte activation, the dynamic transformation of an oocyte into an embryo, is largely driven by Ca²⁺ oscillations that vary in duration and amplitude across species.
McLennan, H.J. +4 more
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Reproductive Medicine and Biology, 2023 Background First successful human round spermatid injection (ROSI) was conducted by Tesarik et al. in 1996 for the sole treatment of nonobstructive azoospermic men whose most advanced spermatogenic cells were elongating round spermatids.
Atsushi Tanaka, Seiji Watanabe
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Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
Oocyte-dependent activation of MTOR in cumulus cells controls the development and survival of cumulus-oocyte complexes. [PDF]
, 2016 Communication between oocytes and their companion somatic cells promotes the healthy development of ovarian follicles, which is crucial for producing oocytes that can be fertilized and are competent to support embryogenesis.
Su, You-Qiang +11 more
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Czech Journal of Animal Science, 2007 Porcine oocytes matured in vitro were activated for parthenogenetic development using either calcium ionophore (50μM for 10 min) or nitric oxide donor SNAP (2mM for 23.5 hours).
J. Petr +4 more
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LACTATE DEHYDROGENASE ACTIVITY IN THE OOCYTES OF MAMMALS [PDF]
Reproduction, 1968 Summary. The mature oocyte dissected from the post-pubertal ovary has a lactate dehydrogenase activity similar to that found in the newly ovulated ovum in the mouse, rat, hamster and rabbit. There is very little interstrain or interbreed variation in ldh activity in the mouse and rabbit.
openaire +2 more sources
Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source
Artificial oocyte activation with calcium ionophore for frozen sperm cycles [PDF]
, 2018 WOS: 000445003100007PubMed ID: 29620419Fertilization problems are the major problems that may be faced in 30-55% of the patients during an intracytoplasmic sperm injection (ICSI) cycle.
Keskin, İlknur +4 more
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Advanced Science, EarlyView.STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang +8 more
wiley +1 more source