Results 41 to 50 of about 79,883 (298)
Oocyte activation deficiency: a role for an oocyte contribution? [PDF]
Human Reproduction Update, 2015 Infertility affects between 10 and 16% of couples worldwide. Twenty to 30% of cases of infertility are due to a male factor, 20-35% to a female factor, and 25-40% are due to both male and female factors. In ∼10-25% of cases, the precise underlying cause remains unclear.
Yeste, M +4 more
openaire +3 more sources
Porcine oocyte maturation in vitro : role of cAMP and oocyte-secreted factors: a practical approach [PDF]
, 2016 Polyspermy or the penetration of more than one sperm cell remains a problem during porcine in vitro fertilization (IVF). After in vitro culture of porcine zygotes, only a low percentage of blastocysts develop and their quality is inferior to that of in ...
Appeltant, Ruth +4 more
core +2 more sources
MicroRNA Activity Is Suppressed in Mouse Oocytes [PDF]
Current Biology, 2010 MicroRNAs (miRNAs) are small endogenous RNAs that typically imperfectly base pair with 3' untranslated regions (3'UTRs) and mediate translational repression and mRNA degradation. Dicer, which generates small RNAs in the miRNA and RNA interference (RNAi) pathways, is essential for meiotic maturation of mouse oocytes.
Ma, J. +7 more
openaire +4 more sources
Zinc Dynamics during Drosophila Oocyte Maturation and Egg Activation
iScience, 2020 Summary: Temporal fluctuations in zinc concentration are essential signals, including during oogenesis and early embryogenesis. In mammals, zinc accumulation and release are required for oocyte maturation and egg activation, respectively.
Qinan Hu +6 more
doaj +1 more source
Managing the Oocyte Meiotic Arrest—Lessons from Frogs and Jellyfish
Cells, 2020 During oocyte development, meiosis arrests in prophase of the first division for a remarkably prolonged period firstly during oocyte growth, and then when awaiting the appropriate hormonal signals for egg release. This prophase arrest is finally unlocked
Catherine Jessus +2 more
doaj +1 more source
Evidence for Integrin Venus Kinase Receptor 1 Alliance in the Ovary of Schistosoma mansoni Females Controlling Cell Survival [PDF]
, 2017 Parasites of the genus Schistosoma cause schistosomiasis, a life-threatening infectious disease for humans and animals worldwide. Among the remarkable biological features of schistosomes is the differentiation of the female gonads which is controlled by ...
Cailliau, Katia +5 more
core +5 more sources
NLRP2 controls age-associated maternal fertility [PDF]
, 2016 Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are well-known for their key roles in the immune system. Ectopically expressed NLRP2 in immortalized cell lines assembles an inflammasome and inhibits activation of the proinflammatory ...
Agostini +24 more
core +2 more sources
How do spermatozoa activate oocytes? [PDF]
Reproductive BioMedicine Online, 2010 Although the spermatozoon is 500,000 times smaller in volume than the oocyte, it induces rapid and dramatic changes in oocyte physiology that lead to meiosis re-initiation. These oocyte activation events are described here, as is the evidence for a soluble activating factor in the spermatozoon.
Brian, Dale +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Journal of Human Reproductive Sciences, 2018 Globozoospermia, characterized by round-headed acrosomeless sperm, is a rare and severe form of teratozoospermia. We report a successful pregnancy in two cases of total globozoospermia after intracytoplasmic sperm injection (ICSI) with oocyte activation ...
Puneet Kaur Kochhar, Pranay Ghosh
doaj +1 more source