A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes [PDF]
, 1995 In many tissues, inwardly rectifying K channels are coupled to seven- helix receptors via the Gi/Go family of heterotrimeric G proteins. This activation proceeds at least partially via G beta gamma subunits.
Dascal, Nathan +4 more
core +2 more sources
Regulation of the G2/M Transition in Rodent Oocytes [PDF]
, 2010 Regulation of maturation in meiotically competent mammalian oocytes is a complex process involving the carefully coordinated exchange of signals between the somatic and germ cell compartments of the ovarian follicle via paracrine and cell–cell coupling ...
Downs, Stephen
core +2 more sources
Production of mouse offspring from inactivated spermatozoa using horse PLCζ mRNA
The Journal of Reproduction and Development, 2019 Improving artificial oocyte activation is essential for assisted reproduction or animal biotechnology that can obtain healthy offspring with a high success rate.
Yunosuke YAMAMOTO +6 more
doaj +1 more source
Preimplantation Developmental Competence of Bovine and Porcine Oocytes Activated by Zinc Chelation
Animals, 2022 After sperm-oocyte fusion, intracytoplasmic rises of calcium (Ca) induce the release of zinc (Zn) out of the oocyte (Zn sparks). Both phenomena are known to play an essential role in the oocyte activation process.
Juan P. Cabeza +5 more
doaj +1 more source
Stac3 enhances expression of human CaV1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels. [PDF]
, 2018 Mutations of CaV1.1, the pore-forming subunit of the L-type Ca2+ channel in skeletal muscle, are an established cause of hypokalemic periodic paralysis (HypoPP).
Cannon, Stephen C +3 more
core +1 more source
Microinjected Xenopus oocytes synthesize active human plasminogen activator [PDF]
Nucleic Acids Research, 1981 Induction of synthesis of the protease plasminogen activator (PA) by hormones, oncogenic viruses and tumor promoters occurs at the transcription level. A novel bioassay for PA messenger RNA was developed to study the regulation of PA synthesis and the genetic elements involved in it.
R, Miskin, H, Soreq
openaire +2 more sources
Osmolarity-regulated swelling initiates egg activation in Drosophila
Open Biology, 2021 Egg activation is a series of highly coordinated processes that prepare the mature oocyte for embryogenesis. Typically associated with fertilization, egg activation results in many downstream outcomes, including the resumption of the meiotic cell cycle ...
Anna H. York-Andersen +4 more
doaj +1 more source
Stimulation of TRPV1 by green laser light [PDF]
, 2012 Low-level laser irradiation of visible light had been introduced as a medical treatment already more than 40 years ago, but its medical application still remains controversial.
Gu, Quanbao +3 more
core +2 more sources
Methylglyoxal-dependent glycative stress and deregulation of SIRT1 functional network in the ovary of PCOS mice [PDF]
, 2020 Advanced glycation end-products (AGEs) are involved in the pathogenesis and consequences of polycystic ovary syndrome (PCOS), a complex metabolic disorder associated with female infertility.
Amicarelli, F +10 more
core +1 more source
Fatty Acid Oxidation and Meiotic Resumption in Mouse Oocytes [PDF]
, 2009 We have examined the potential role of fatty acid oxidation (FAO) in AMP-activated protein kinase (AMPK)-induced meiotic maturation. Etomoxir and malonyl CoA, two inhibitors of carnitine palmitoyl transferase-1 (CPT1), and thus FAO, blocked meiotic ...
Downs, Stephen +2 more
core +2 more sources