Oocyte activation deficiency: a role for an oocyte contribution? [PDF]
Human Reproduction Update, 2016 Infertility affects between 10 and 16% of couples worldwide. Twenty to 30% of cases of infertility are due to a male factor, 20-35% to a female factor, and 25-40% are due to both male and female factors. In ∼10-25% of cases, the precise underlying cause remains unclear.
Marc Yeste +2 more
exaly +6 more sources
Chloroquine inhibits artificial oocyte activation induced by ethanol or Sr2+ but not by sperm in mice [PDF]
The Journal of Reproduction and DevelopmentCalcium release from the endoplasmic reticulum via sperm-derived phospholipase C zeta is crucial for oocyte activation during fertilization. Chloroquine (CQ) inhibits the increase in cytoplasmic calcium.
Tadashi YAMAZAKI +2 more
doaj +2 more sources
Fertility and Sterility, 2019 OBJECTIVE To investigate the extent to which assisted oocyte activation (AOA) improves clinical outcomes in patients diagnosed with oocyte activation deficiencies (OADs).
Davina Bonte +2 more
exaly +2 more sources
Artificial oocyte activation: physiological, pathophysiological and ethical aspects
Systems Biology in Reproductive Medicine, 2018 Infertile couples with low oocyte yield in combination with abnormal semen parameters may experience intra-cytoplasmic sperm injection (ICSI) failure. An established factor associated with ICSI failure is oocyte activation deficiency (AOD).
G. Anifandis +9 more
semanticscholar +2 more sources
Oocyte activation with phospholipase Cζ mRNA induces repetitive intracellular Ca2+ rises and improves the quality of pig embryos after intracytoplasmic sperm injection [PDF]
The Journal of Reproduction and DevelopmentFor the intracytoplasmic sperm injection (ICSI) procedure in pigs, an electrical pulse (EP) has been used as an effective method for oocyte stimulation, but unlike sperm, EP is unable to induce Ca2+ oscillations.
Michiko NAKAI +4 more
doaj +2 more sources
Activation of Proteolysis During Oocyte In Vitro Maturation
Molecular Reproduction and DevelopmentABSTRACTIn vitro maturation (IVM) is a form of assisted reproductive technology (ART) applied to obtain mature oocytes in culture. Decline in IVM success rates by age has led consideration of novel approaches based on cellular dynamics. Our aim was to achieve proteostasis in old bovine oocytes from 13 to 16‐year‐old bovine with a lower potential for ...
Filiz Tepekoy, Berk Bulut, Erdal Karaoz
openaire +7 more sources
Comparison of Human Oocyte Activation Between Round-Headed Sperm Injection Followed by Calcium Ionophore Treatment and Normal Sperm Injection in a Patient With Globozoospermia [PDF]
Frontiers in Endocrinology, 2020 Fertilization failure is common in patients with round-headed sperm, a form of globozoospermia. Artificial oocyte activation is able to assist oocyte fertilization after sperm injection in these patients.
Xiangli Niu +3 more
doaj +2 more sources
Cell ReportsSummary: ERK activity oscillates between sustained activation during oocyte formation and transient inactivation during oocyte maturation, fertilization, and early embryogenesis.
Han Bit Baek +4 more
doaj +3 more sources
Calcineurin role in porcine oocyte activation
Animal, 2016 Calcineurin is required for oocyte exit from meiotic block in metaphase II (MII) stage in invertebrates and also in lower vertebrates. However, the role of calcineurin in mammalian oocyte activation is still unclear.
L. Tůmová +7 more
doaj +3 more sources
Bovine oocyte activation with bull or human sperm by conventional ICSI and Piezo-ICSI: Its relationship with PLCɀ activity [PDF]
Open Veterinary JournalBackground: Intracytoplasmic sperm injection (ICSI) technique has low efficiency in cattle. This has mainly been attributed to the oocyte activation failure due to oocyte and/or sperm factors.
Gabriel Martín Alvarez +7 more
doaj +2 more sources