Activation of Proteolysis During Oocyte In Vitro Maturation [PDF]
ABSTRACTIn vitro maturation (IVM) is a form of assisted reproductive technology (ART) applied to obtain mature oocytes in culture. Decline in IVM success rates by age has led consideration of novel approaches based on cellular dynamics. Our aim was to achieve proteostasis in old bovine oocytes from 13 to 16‐year‐old bovine with a lower potential for ...
Filiz Tepekoy, Berk Bulut, Erdal Karaoz
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Oocyte activation with phospholipase Cζ mRNA induces repetitive intracellular Ca2+ rises and improves the quality of pig embryos after intracytoplasmic sperm injection [PDF]
For the intracytoplasmic sperm injection (ICSI) procedure in pigs, an electrical pulse (EP) has been used as an effective method for oocyte stimulation, but unlike sperm, EP is unable to induce Ca2+ oscillations.
Michiko NAKAI +4 more
doaj +2 more sources
Calcineurin role in porcine oocyte activation
Calcineurin is required for oocyte exit from meiotic block in metaphase II (MII) stage in invertebrates and also in lower vertebrates. However, the role of calcineurin in mammalian oocyte activation is still unclear.
L. Tůmová +7 more
doaj +3 more sources
ERK activation dynamics in maturing oocyte controls embryonic nuclear divisions in Caenorhabditis elegans [PDF]
Summary: ERK activity oscillates between sustained activation during oocyte formation and transient inactivation during oocyte maturation, fertilization, and early embryogenesis.
Han Bit Baek +4 more
doaj +3 more sources
Comparison of Human Oocyte Activation Between Round-Headed Sperm Injection Followed by Calcium Ionophore Treatment and Normal Sperm Injection in a Patient With Globozoospermia [PDF]
Fertilization failure is common in patients with round-headed sperm, a form of globozoospermia. Artificial oocyte activation is able to assist oocyte fertilization after sperm injection in these patients.
Xiangli Niu +3 more
doaj +2 more sources
Bovine oocyte activation with bull or human sperm by conventional ICSI and Piezo-ICSI: Its relationship with PLCɀ activity [PDF]
Background: Intracytoplasmic sperm injection (ICSI) technique has low efficiency in cattle. This has mainly been attributed to the oocyte activation failure due to oocyte and/or sperm factors.
Gabriel Martín Alvarez +7 more
doaj +2 more sources
Assisted Oocyte Activation Method (Ca ACTIVATION) Improves Fertilization in Patients with Recurrent Fertilization Failure [PDF]
: Total fertilization failure (TFF) happens in 1–3% of total intracytoplasmic sperm injection (ICSI) cycles and may reoccur in sequent cycles. Regardless the high success rate with the applying of intracytoplasmic sperm injection (ICSI), there's still a ...
Mohammed H. Sayed Ahmad +2 more
core +1 more source
Though the application of advanced assisted reproductive technologies, such as in vitro fertilization and intracytoplasmic sperm injection (ICSI), circumvents many factors resulting in infertility, it still has its challenges.
P. M. Gopinath, Hema Vaithianathan
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Phospholipase C Zeta 1 (PLCZ1) is considered a major sperm-borne oocyte activation factor. After gamete fusion, PLCZ1 triggers calcium oscillations in the oocyte, resulting in oocyte activation.
Raul A. Gonzalez-Castro +1 more
doaj +1 more source
Oocyte activation inefficiency is one of the reasons for female infertility and Ca2+ functions play a critical role in the regulation of oocyte activation.
Feng Wang +8 more
doaj +1 more source

