Results 11 to 20 of about 1,544,426 (289)

Oocyte activation deficiency: a role for an oocyte contribution? [PDF]

Human Reproduction Update, 2015
Infertility affects between 10 and 16% of couples worldwide. Twenty to 30% of cases of infertility are due to a male factor, 20-35% to a female factor, and 25-40% are due to both male and female factors. In ∼10-25% of cases, the precise underlying cause remains unclear.
Yeste, M, Jones, C, Amdani, S, Patel, S, Coward, K   +4 more
openaire   +4 more sources

Activation of Proteolysis During Oocyte In Vitro Maturation [PDF]

Molecular Reproduction and Development
ABSTRACTIn vitro maturation (IVM) is a form of assisted reproductive technology (ART) applied to obtain mature oocytes in culture. Decline in IVM success rates by age has led consideration of novel approaches based on cellular dynamics. Our aim was to achieve proteostasis in old bovine oocytes from 13 to 16‐year‐old bovine with a lower potential for ...
Filiz Tepekoy, Berk Bulut, Erdal Karaoz
openaire   +6 more sources

Bovine oocyte activation with bull or human sperm by conventional ICSI and Piezo-ICSI: Its relationship with PLCɀ activity [PDF]

Open Veterinary Journal
Background: Intracytoplasmic sperm injection (ICSI) technique has low efficiency in cattle. This has mainly been attributed to the oocyte activation failure due to oocyte and/or sperm factors.
Gabriel Martín Alvarez, Sofía Villanueva, Elizabeth Breininger, Marisa Geller, Claudio Ruhlmann, Gabriel Carlos Dalvit, Pablo Daniel Cetica, Masashige Kuwayama   +7 more
doaj   +2 more sources

Calcineurin role in porcine oocyte activation

Animal, 2016
Calcineurin is required for oocyte exit from meiotic block in metaphase II (MII) stage in invertebrates and also in lower vertebrates. However, the role of calcineurin in mammalian oocyte activation is still unclear.
L. Tůmová, E. Chmelíková, T. Žalmanová, V. Kučerová-Chrpová, R. Romar, M. Dvořáková, K. Hošková, J. Petr   +7 more
doaj   +3 more sources

Phospholipase C Zeta 1 (PLCZ1): The Function and Potential for Fertility Assessment and In Vitro Embryo Production in Cattle and Horses

Veterinary Sciences, 2023
Phospholipase C Zeta 1 (PLCZ1) is considered a major sperm-borne oocyte activation factor. After gamete fusion, PLCZ1 triggers calcium oscillations in the oocyte, resulting in oocyte activation.
Raul A. Gonzalez-Castro, Elaine M. Carnevale   +1 more
doaj   +1 more source

Oocyte activation

The Onco Fertility Journal, 2021
Though the application of advanced assisted reproductive technologies, such as in vitro fertilization and intracytoplasmic sperm injection (ICSI), circumvents many factors resulting in infertility, it still has its challenges.
P. M. Gopinath, Hema Vaithianathan
openaire   +1 more source

Regulation of [Ca2+]i oscillations and mitochondrial activity by various calcium transporters in mouse oocytes

Reproductive Biology and Endocrinology, 2020
Oocyte activation inefficiency is one of the reasons for female infertility and Ca2+ functions play a critical role in the regulation of oocyte activation.
Feng Wang, Ang Li, Tie-Gang Meng, Le-Yun Wang, Li-Juan Wang, Yi Hou, Heide Schatten, Qing-Yuan Sun, Xiang-Hong Ou   +8 more
doaj   +1 more source

Mitochondrial Ca2 + Is Related to Mitochondrial Activity and Dynamic Events in Mouse Oocytes

Frontiers in Cell and Developmental Biology, 2020
Mitochondrial energy insufficiency is strongly associated with oocyte activation disorders. Ca2+, especially that in the mitochondrial matrix, plays a pivotal role in mitochondrial energy supplementation, but the underlying mechanisms are still only ...
Feng Wang, Feng Wang, Tie-Gang Meng, Tie-Gang Meng, Jian Li, Yi Hou, Shi-Ming Luo, Heide Schatten, Qing-Yuan Sun, Qing-Yuan Sun, Xiang-Hong Ou   +10 more
doaj   +1 more source

Applications of advances in mRNA-based platforms as therapeutics and diagnostics in reproductive technologies

Frontiers in Cell and Developmental Biology, 2023
The recent COVID-19 pandemic led to many drastic changes in not only society, law, economics, but also in science and medicine, marking for the first time when drug regulatory authorities cleared for use mRNA-based vaccines in the fight against this ...
Wjdan S. Bafleh, Haia M. R. Abdulsamad, Sally M. Al-Qaraghuli, Riwa Y. El Khatib, Rawdah Taha Elbahrawi, Azhar Mohamud Abdukadir, Shaima M. Alsawae, Zakia Dimassi, Hamdan Hamdan, Hamdan Hamdan, Junaid Kashir, Junaid Kashir   +11 more
doaj   +1 more source

Assisted Oocyte Activation Method (Ca ACTIVATION) Improves Fertilization in Patients with Recurrent Fertilization Failure

, 2022
: Total fertilization failure (TFF) happens in 1–3% of total intracytoplasmic sperm injection (ICSI) cycles and may reoccur in sequent cycles. Regardless the high success rate with the applying of intracytoplasmic sperm injection (ICSI), there's still a ...
Mohammed H. Sayed Ahmad, Bahgat A. El-Fiky, Ayman S. El-Dorghamy   +2 more
core   +1 more source