Results 11 to 20 of about 79,883 (298)

Calcineurin role in porcine oocyte activation

open access: yesAnimal, 2016
Calcineurin is required for oocyte exit from meiotic block in metaphase II (MII) stage in invertebrates and also in lower vertebrates. However, the role of calcineurin in mammalian oocyte activation is still unclear.
L. Tůmová   +7 more
doaj   +3 more sources

Bovine oocyte activation with bull or human sperm by conventional ICSI and Piezo-ICSI: Its relationship with PLCɀ activity [PDF]

open access: yesOpen Veterinary Journal
Background: Intracytoplasmic sperm injection (ICSI) technique has low efficiency in cattle. This has mainly been attributed to the oocyte activation failure due to oocyte and/or sperm factors.
Gabriel Martín Alvarez   +7 more
doaj   +2 more sources

Cortical granule exocytosis is mediated by alpha-SNAP and N-Ethilmaleimide sensitive factor in mouse eggs [PDF]

open access: yes, 2015
Cortical granule exocytosis (CGE), also known as cortical reaction, is a calciumregulated secretion that represents a membrane fusion process during meiotic cell division of eggs.
Bello, Oscar Daniel   +2 more
core   +11 more sources

Oocyte activation

open access: yesThe Onco Fertility Journal, 2021
Though the application of advanced assisted reproductive technologies, such as in vitro fertilization and intracytoplasmic sperm injection (ICSI), circumvents many factors resulting in infertility, it still has its challenges.
P. M. Gopinath, Hema Vaithianathan
openaire   +1 more source

Phospholipase C Zeta 1 (PLCZ1): The Function and Potential for Fertility Assessment and In Vitro Embryo Production in Cattle and Horses

open access: yesVeterinary Sciences, 2023
Phospholipase C Zeta 1 (PLCZ1) is considered a major sperm-borne oocyte activation factor. After gamete fusion, PLCZ1 triggers calcium oscillations in the oocyte, resulting in oocyte activation.
Raul A. Gonzalez-Castro   +1 more
doaj   +1 more source

Regulation of [Ca2+]i oscillations and mitochondrial activity by various calcium transporters in mouse oocytes

open access: yesReproductive Biology and Endocrinology, 2020
Oocyte activation inefficiency is one of the reasons for female infertility and Ca2+ functions play a critical role in the regulation of oocyte activation.
Feng Wang   +8 more
doaj   +1 more source

Mitochondrial Ca2 + Is Related to Mitochondrial Activity and Dynamic Events in Mouse Oocytes

open access: yesFrontiers in Cell and Developmental Biology, 2020
Mitochondrial energy insufficiency is strongly associated with oocyte activation disorders. Ca2+, especially that in the mitochondrial matrix, plays a pivotal role in mitochondrial energy supplementation, but the underlying mechanisms are still only ...
Feng Wang   +10 more
doaj   +1 more source

Applications of advances in mRNA-based platforms as therapeutics and diagnostics in reproductive technologies

open access: yesFrontiers in Cell and Developmental Biology, 2023
The recent COVID-19 pandemic led to many drastic changes in not only society, law, economics, but also in science and medicine, marking for the first time when drug regulatory authorities cleared for use mRNA-based vaccines in the fight against this ...
Wjdan S. Bafleh   +11 more
doaj   +1 more source

The Cyclin B2/CDK1 Complex Conservatively Inhibits Separase Activity in Oocyte Meiosis II

open access: yesFrontiers in Cell and Developmental Biology, 2021
Recently, we have reported that the cyclin B2/CDK1 complex regulates homologous chromosome segregation through inhibiting separase activity in oocyte meiosis I, which further elucidates the compensation of cyclin B2 on cyclin B1’s function in meiosis I ...
Jian Li   +7 more
doaj   +1 more source

Oocyte maturation in the toad Rhinella arenarum (Amphibia, Anura): Evidence of cAMP involvement in steroid production and action [PDF]

open access: yes, 2018
In this work, we describe the participation of the adenylate cyclase/3′-5′-cyclic adenonsine monophosphate (cAMP) pathway in the seasonal follicular secretion of progesterone (P 4 ) and testosterone (T), and its relationship with the maturation of ...
Arias Torres   +48 more
core   +1 more source

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