Results 31 to 40 of about 84,026 (244)
Placebos without deception: a randomized controlled trial in irritable bowel syndrome. [PDF]
PLoS ONE, 2010 Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception.
Ted J Kaptchuk +9 more
doaj +1 more source
Motor- and cognition-related safety of pimavanserin in patients with Parkinson's disease psychosis
Frontiers in Neurology, 2022 BackgroundPimavanserin, a selective 5-HT2A inverse agonist/antagonist, is the only treatment approved by the US Food and Drug Administration for hallucinations and delusions associated with Parkinson's disease (PD) psychosis.AimWe aimed to evaluate motor-
Victor Abler +5 more
doaj +1 more source
Open-label placebos for menopausal hot flushes: a randomized controlled trial [PDF]
Scientific Reports, 2020 AbstractThis study investigated the efficacy of an open-label placebo (OLP) treatment for menopausal hot flushes. Women with at least five moderate or severe hot flushes per day were allocated to receive four weeks of OLP for twice a day or no-treatment. Intention-to-treat analyses included n = 100 women.
Pan, Yiqi +5 more
openaire +2 more sources
Effects of Open- and Closed-Label Nocebo and Placebo Suggestions on Itch and Itch Expectations
Frontiers in Psychiatry, 2019 Placebo and nocebo effects have been shown to influence subjective symptoms such as itch. These effects can be induced by influencing outcome expectations through, for example, combining the application of an inert substance (e.g., a cream) with verbal ...
Stefanie H. Meeuwis +12 more
doaj +1 more source
The role of positive information provision in open‐label placebo effects
Applied Psychology: Health and Well-Being, 2023 Abstract Open label placebos (OLPs) appear generally efficacious among clinical samples, but the empirical evidence regarding their use in non‐clinical and sub‐clinical samples, as well as when administered independent of a convincing rationale, is mixed. Healthy participants ( N
Kirsten Barnes +4 more
openaire +2 more sources
Effects of Open-Label Placebos on State Anxiety and Glucocorticoid Stress Responses [PDF]
Brain Sciences, 2021 Stress belongs to the most frequent negative feelings people are confronted with in daily life. Strategies against acute stress include, e.g., relaxation techniques or medications, but it is also known that placebos can successfully reduce negative emotional stress.
Schaefer, Michael +2 more
openaire +3 more sources
Open label placebo: can honestly prescribed placebos evoke meaningful therapeutic benefits?
BMJ, 2018 Results from small clinical trials suggesting that placebos can be ethically and effectively used in clinical practice warrant further study, argue Ted Kaptchuk and Franklin ...
Ted J, Kaptchuk, Franklin G, Miller
openaire +3 more sources
Medicines, 2020 Background: Placebo has been studied for many years and is ever-present in healthcare. In clinical practice, its use is limited by ethical issues raised by the deception entailed by its administration.
Leo Druart +6 more
doaj +1 more source
Frontiers in Medicine, 2020 Enterococcus faecium SF68® (SF68) is a licensed pharmaceutical for treatment and prevention of diarrhea in Austria, Italy and Switzerland. However, as for other probiotics, evidence for its efficacy is based on small to medium-sized studies.
Thomas Greuter +6 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source