Results 41 to 50 of about 22,278,301 (236)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Decolonizing the Engineering Curriculum

, 2022
Decolonizing the Engineering Curriculum is a set of adaptable resources developed to enable Engineering faculty to include Indigenous reconciliation in engineering courses. [OER Description: This unit plan provides adaptable resources developed to enable
Rattray, Curtis, Wolf, Pamela, Shaw, James, Harris, Ben, Gonzalez, Alex, Saha, Debalina, Martinussen, Nika   +6 more
core   +1 more source

Open Assessment of Learning: A Meta-Synthesis

International Review of Research in Open and Distributed Learning, 2016
Open Assessment of Learning (OAoL) is an emerging educational concept derived from the incorporation of Information and Communication Technologies (ICT) to education and is related with the Open Education Movement.
Andres Chiappe, Ricardo Alfonso Pinto, Vivian Arias   +2 more
doaj   +1 more source

The Open Page Project

Journal of Teaching and Learning, 2020
This paper overviews an Open Educational Resource (OER) project aimed at developing digital literacies and open educational practice within a Faculty of Education.
Bonnie Stewart
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Future Proofing Higher Education in the Pacific with Open and Flexible Learning

Journal of Learning for Development, 2018
Affordable access to higher education is a major challenge for small Pacific island nations. The University of the South Pacific which is owned and governed by twelve island nations in this region plays a special role in meeting this challenge.
Som Naidu, Keith Roberts
doaj  

Extending the Territory: From Open Educational Resources to Open Educational Practices

Journal of Open, Flexible and Distance Learning
This article examines the findings of the recent OPAL report Beyond OER: Shifting Focus from Resources to Practices. In doing so, it defines current understanding of open educational resources and open educational practices, and highlights the shift from
Ulf-Daniel Ehlers
doaj   +1 more source

An investigation into social learning activities by practitioners in open educational practices

International Review of Research in Open and Distributed Learning, 2014
By investigating how educational practitioners participate in activities around open educational practices (OEP), this paper aims at contributing to an understanding of open practices and how these practitioners learn to use OEP.
Bieke Schreurs, Antoine Van den Beemt, Fleur Prinsen, Gabi Witthaus, Grainne Conole, Maarten de Laat   +5 more
doaj   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Videobasiertes Lehr-Lernszenario in der Hochschule – theoretischer Hintergrund und struktureller Rahmen eines Praxisbeispiels zur Wertebildung

Bibliothek
Videobasierte Lehr-Lernszenarien bieten hervorragende Möglichkeiten, eine Brücke zur Praxis zu schlagen und die professionelle Wahrnehmung von Lernenden zu schulen.
Eckert Johanna, Zeelen Tim
doaj   +1 more source