Results 61 to 70 of about 1,168,745 (259)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The value of GenAI for peer feedback provision: student perceptions and impacts

International Journal of Educational Technology in Higher Education
Generative Artificial Intelligence (GenAI) has sparked a global debate on its potential as a feedback source for students, yet research in this area remains limited. This study explores students’ use of GenAI during peer feedback provision.
Omid Noroozi, Golnoush Haddadian, Xingshi Gao, Christian Schunn, Maryam Alqassab, Seyyed Kazem Banihashem   +5 more
doaj   +1 more source

Self-directed learning skills for ODeL students in crisis situations: lessons from Zimbabwe Open University during Covid-19

Frontiers in Education
This study explores self-directed learning skills utilized by students at Zimbabwe Open University, Masvingo regional campus during the Covid-19 pandemic with the aim of identifying context-specific skills that can prepare ODeL students for future crisis
Logic Magwa, Johannes Nkosinathi Zongozzi   +1 more
doaj   +1 more source

Utilizing random forest algorithm for early detection of academic underperformance in open learning environments. [PDF]

PeerJ Comput Sci, 2023
Balabied SAA, Eid HF.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Sedentary Patterns and Sit-to-Stand Transitions in Open Learning Spaces and Conventional Classrooms among Primary School Students. [PDF]

Int J Environ Res Public Health, 2022
Hartikainen J, Haapala EA, Sääkslahti A, Poikkeus AM, Finni T.   +4 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Making long-term memories in minutes: a time pattern from memory research in education

Frontiers in Human Neuroscience, 2013
Memory systems select from environmental stimuli those to encode permanently. Repeated stimuli separated by timed spaces without stimuli can initiate Long-Term Potentiation (LTP) and long-term memory (LTM) encoding. These processes occur in time scales
Paul eKelley, Terry eWhatson
doaj   +1 more source

Exploring students' learning experience in online education: analysis and improvement proposals based on the case of a Spanish open learning university. [PDF]

Educ Technol Res Dev, 2021
Rivera-Vargas P, Anderson T, Cano CA.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source