Results 41 to 50 of about 1,409,999 (372)
Evolutionary divergence of novel open reading frames in cichlids speciation [PDF]
Scientific Reports, 2020 AbstractNovel open reading frames (nORFs) with coding potential may arise from noncoding DNA. Not much is known about their emergence, functional role, fixation in a population or contribution to adaptive radiation. Cichlids fishes exhibit extensive phenotypic diversification and speciation.
Yagnesh Urmania +12 more
openaire +8 more sources
The Hepatitis E Virus Open Reading Frame 2 Protein: Beyond Viral Capsid
Frontiers in Microbiology, 2021 Hepatitis E virus (HEV) is a zoonotic pathogen causing hepatitis in both human and animal hosts, which is responsible for acute hepatitis E outbreaks worldwide. The 7.2 kb genome of the HEV encodes three well-defined open reading frames (ORFs), where the
Zhaobin Zhou +6 more
doaj +1 more source
PAX6 mutations: genotype-phenotype correlations [PDF]
, 2005 BACKGROUND: The PAX6 protein is a highly conserved transcriptional regulator that is important for normal ocular and neural development. In humans, heterozygous mutations of the PAX6 gene cause aniridia (absence of the iris) and related developmental eye
Hanson, Isabel M +2 more
core +3 more sources
Identification of a protein encoded in the EB-viral open reading frame BMRF2 [PDF]
, 1992 Using monospecific rabbit sera against a peptide derived from a potential antigenic region of the Epstein-Barr viral amino acid sequence encoded in the open reading frame BMRF2 we could identify a protein-complex of 53/55 kDa in chemically induced B95-8,
A. v. Brunn +37 more
core +2 more sources
Conserved upstream open reading frames in higher plants [PDF]
BMC Genomics, 2008 Abstract Background Upstream open reading frames (uORFs) can down-regulate the translation of the main open reading frame (mORF) through two broad mechanisms: ribosomal stalling and reducing reinitiation efficiency. In distantly related plants, such as rice and Arabidopsis, it has been found that conserved uORFs are ...
Tran, M., Schultz, C., Baumann, U.
openaire +5 more sources
Molecular Plant-Microbe Interactions, 1999 The cell wall acts as the first line of defense during pathogen invasion. Polygalacturonases (PGs) are a class of cell-wall-modifying enzymes with precise temporal and organ-specific expression.
Ramamurthy Mahalingam +2 more
doaj +1 more source
OrfM: a fast open reading frame predictor for metagenomic data
Bioinform., 2016 Summary: Finding and translating stretches of DNA lacking stop codons is a task common in the analysis of sequence data. However, the computational tools for finding open reading frames are sufficiently slow that they are becoming a bottleneck as the ...
B. Woodcroft, J. Boyd, G. Tyson
semanticscholar +1 more source
Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements. [PDF]
, 2017 In single stranded (+)-sense RNA viruses, RNA structural elements (SEs) play essential roles in the infection process from replication to encapsidation.
Aviran, Sharon +5 more
core +2 more sources
Biochemical and Biophysical Research Communications, 2000 The suppressor of cytokine signalling 1 protein (SOCS-1) belongs to a novel family of cytokine inducible factors which function as inhibitors of the JAK/STAT pathway. While SOCS-1 previously has been described as a single-exon gene, here we present evidence for an additional 5' exon, separated by a 509 bp intron from exon 2.
Schluter, G. +2 more
openaire +4 more sources
TRAPID : an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes [PDF]
, 2013 Transcriptome analysis through next-generation sequencing technologies allows the generation of detailed gene catalogs for non-model species, at the cost of new challenges with regards to computational requirements and bioinformatics expertise.
Deforce, Dieter +5 more
core +2 more sources