Results 61 to 70 of about 276,768 (304)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Transcriptome analysis of Taenia solium cysticerci using Open Reading Frame ESTs (ORESTES)

open access: yesParasites & Vectors, 2009
Background Human infection by the pork tapeworm Taenia solium affects more than 50 million people worldwide, particularly in underdeveloped and developing countries. Cysticercosis which arises from larval encystation can be life threatening and difficult
Tyler Kevin M   +15 more
doaj   +1 more source

Identification of short open reading frames in plant genomes

open access: yesFrontiers in Plant Science, 2023
The roles of short/small open reading frames (sORFs) have been increasingly recognized in recent years due to the rapidly growing number of sORFs identified in various organisms due to the development and application of the Ribo-Seq technique, which sequences the ribosome-protected footprints (RPFs) of the translating mRNAs.
Yong Feng   +5 more
openaire   +3 more sources

Screen shot of Artemis showing GC Frame Plot and a wrong reading frame.

open access: yes, 2014
The GC frame plot shows a sliding window of the third codon position GC content for the three forward reading frames. The red line in the GC frame plot corresponds to the +1 reading frame, the green line corresponds to the +2 reading frame and blue line ...
LaTia Etheredge Scott (534326)   +1 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Frameshifting in the P6 cDNA Phage Display System

open access: yesMolecules, 2010
Phage display is a powerful technique that enables easy identification of targets for any type of ligand. Targets are displayed at the phage surface as a fusion protein to one of the phage coat proteins.
Veerle Somers   +3 more
doaj   +1 more source

Upstream Open Reading Frames as Regulators of mRNA Translation [PDF]

open access: yesMolecular and Cellular Biology, 2000
Continuing discoveries of new and surprising mechanisms of gene regulation suggest that our understanding of this complex and ubiquitous biological process remains incomplete. Emerging examples illustrate that many and perhaps all genes are regulated at multiple steps including transcription, posttranscriptional processing, nuclear export and ...
D R, Morris, A P, Geballe
openaire   +2 more sources

Open reading frame (ORF) length distribution from all contigs of M. amblycephala.

open access: yes, 2012
Open reading frame (ORF) length distribution from all contigs of M. amblycephala.
Cong Zeng (145162)   +6 more
core   +1 more source

Evidence for adaptive selection on the full open reading frame (ORF) of the JEV genome according to different assessment models.

open access: yes, 2023
Evidence for adaptive selection on the full open reading frame (ORF) of the JEV genome according to different assessment models.
Guowei Wang (1715704)   +15 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

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