Results 81 to 90 of about 276,768 (304)

A Novel pH-Regulated, Unusual 603 bp Overlapping Protein Coding Gene pop Is Encoded Antisense to ompA in Escherichia coli O157:H7 (EHEC)

Frontiers in Microbiology, 2020
Antisense transcription is well known in bacteria. However, translation of antisense RNAs is typically not considered, as the implied overlapping coding at a DNA locus is assumed to be highly improbable.
Barbara Zehentner, Zachary Ardern, Michaela Kreitmeier, Siegfried Scherer, Siegfried Scherer, Klaus Neuhaus, Klaus Neuhaus   +6 more
doaj   +1 more source

Open reading frame analysis of the four larval midgut-predominant genes in Spodoptera litura.

, 2013
Open reading frame analysis of the four larval midgut-predominant genes in Spodoptera litura.
Wen-yin He (328143), Zhong-chen Rao (328146), Wei-hua Xu (5652397), Dao-hua Zhou (328149), Si-chun Zheng (328151), Qi-li Feng (5652400)   +5 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A Kunitz Type Protease Inhibitor Gene JcKTI High Expressed in the Roots and Stems of Jatropha curcas Showing Anti-pest Activity

四川大学学报. 自然科学版, 2016
The open reading frame (ORF) fragment of a Kunitz type protease inhibitor gene JcKTI was cloned by the RT-PCR and PCR technology, respectively, from the leaf cDNA and genomic DNA of Jatropha curcas.
NIU Bei, LI Rui, YANG Lin, FU Jia, TANG Lin, XU Ying   +5 more
doaj  

Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity

mBio, 2017
Neurospora crassa cpc-1 and Saccharomyces cerevisiae GCN4 are homologs specifying transcription activators that drive the transcriptional response to amino acid limitation.
Ivaylo P. Ivanov, Jiajie Wei, Stephen Z. Caster, Kristina M. Smith, Audrey M. Michel, Ying Zhang, Andrew E. Firth, Michael Freitag, Jay C. Dunlap, Deborah Bell-Pedersen, John F. Atkins, Matthew S. Sachs   +11 more
doaj   +1 more source

A Novel Epstein-Barr Virus Glycoprotein gp150 Expressed from the BDLF3 Open Reading Frame

, 1995
Analysis of cDNAs mapping to the BamHI D fragment of the Epstein-Barr virus (EBV) genome indicates that the BDLF3 open reading frame, which is predicted to encode a type 1 membrane protein of 234 amino acids, is expressed as an unspliced message ...
Heineman, Thomas, Kurilla, Michael G., Kieff, Elliott, Davenport, Lisa C., Hutt-Fletcher, Lindsey M.   +4 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Fusion of the Tumor-Suppressor Gene CHEK2 and the Gene for the Regulatory Subunit B of Protein Phosphatase 2 PPP2R2A in Childhood Teratoma

Neoplasia: An International Journal for Oncology Research, 2006
We characterized the molecular genetic consequences of a balanced chromosome translocation t(8;22)(p21; q12), which occurred as the sole cytogenetic aberration in short-term cultured cells from an intrathoracic mature teratoma in a 15-year-old girl ...
Yuesheng Jin, Fredrik Mertens, Carl-Magnus Kullendorff, loannis Panagopoulos   +3 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source