Results 61 to 70 of about 1,440,104 (391)

Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]

, 2011
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A., Evans, D. J., Gould, E. A., Gritsun, T. S., Jones, I. M., Tuplin, A.   +5 more
core   +3 more sources

A novel vector for positive selection of inserts harboring an open reading frame by translational coupling

BioTechniques, 2007
We have developed a novel vector, pTCS, as a tool for efficient selection of open reading frame (ORF)-containing inserts. In pTCS clones containing an insert with an ORF, a downstream marker gene (immE3, conferring resistance to colicin) is activated via
Sumiko Ohashi-Kunihiro, Masafumi Yohda, Haruhiko Masaki, Masayuki Machida   +3 more
doaj   +1 more source

Upstream Open Reading Frames as Regulators of mRNA Translation [PDF]

Molecular and Cellular Biology, 2000
Continuing discoveries of new and surprising mechanisms of gene regulation suggest that our understanding of this complex and ubiquitous biological process remains incomplete. Emerging examples illustrate that many and perhaps all genes are regulated at multiple steps including transcription, posttranscriptional processing, nuclear export and ...
Adam P. Geballe, Adam P. Geballe, David R. Morris   +2 more
openaire   +2 more sources

Characterization of Hemagglutinin Negative Botulinum Progenitor Toxins

Toxins, 2017
Botulism is a disease involving intoxication with botulinum neurotoxins (BoNTs), toxic proteins produced by Clostridium botulinum and other clostridia. The 150 kDa neurotoxin is produced in conjunction with other proteins to form the botulinum progenitor
Suzanne R. Kalb, Jakub Baudys, Theresa J. Smith, Leonard A. Smith, John R. Barr   +4 more
doaj   +1 more source

An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition

Nucleic Acids Research, 2014
Between 6 and 30% of human and mouse transcripts are initiated from transposable elements. However, the promoters driving such transcriptional activity are mostly unknown.
Jingfeng Li, M. Kannan, Anna L. Trivett, Hongling Liao, Xiaolin Wu, K. Akagi, D. Symer   +6 more
semanticscholar   +1 more source

TRAPID : an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes [PDF]

, 2013
Transcriptome analysis through next-generation sequencing technologies allows the generation of detailed gene catalogs for non-model species, at the cost of new challenges with regards to computational requirements and bioinformatics expertise.
Deforce, Dieter, Proost, Sebastian, Van Bel, Michiel, Van de Peer, Yves, Van Neste, Christophe, Vandepoele, Klaas   +5 more
core   +2 more sources

Emerging role of long noncoding RNA-encoded micropeptides in cancer

Cancer Cell International, 2020
Increasing evidence has indicated that long noncoding RNAs (lncRNAs) play various important roles in the development of cancers. The widespread applications of ribosome profiling and ribosome nascent chain complex sequencing revealed that some short open
Mujie Ye, Jingjing Zhang, Meng Wei, Baihui Liu, Kuiran Dong   +4 more
doaj   +1 more source

Molecular Characterisation of Wnt4 and Wnt16 in the Water Flea (Daphnia pulex) and Their Expression Regulation by Polystyrene Nanoplastics

Diversity, 2022
The Wnt gene family is of ancient origin and is involved in various biological processes. In this study, Wnt4 and Wnt16 were cloned from Daphnia pulex, named DpWnt4 and DpWnt16, respectively.
Changan Ma, Di Zuo, Zhiquan Liu
doaj   +1 more source

A single inhibitory upstream open reading frame (uORF) is sufficient to regulate Candida albicans GCN4 translation in response to amino acid starvation conditions

RNA: A publication of the RNA Society, 2014
This study examines translational regulation of the GCN4 mRNA in Candida albicans. Surprisingly, unlike the homologous gene in budding yeast, a single upstream open reading frame is sufficient to regulate GCN4 translation in C. albicans.
Arunkumar Sundaram, C. Grant
semanticscholar   +1 more source

Translational control of Nrf2 within the open reading frame [PDF]

Biochemical and Biophysical Research Communications, 2013
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) is a transcription factor that is essential for the regulation of an effective antioxidant and detoxifying response. The regulation of its activity can occur at transcription, translation and post-translational levels.
Carlos A. Barrero, Salim Merali, Oscar Perez-Leal   +2 more
openaire   +3 more sources