Results 51 to 60 of about 780,027 (226)

From DNA sequence to application: possibilities and complications [PDF]

, 1999
The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages.
A Bruttin, A Bruttin, A Kraus, A Nauta, A Nauta, A Nauta, A Sazicu, AK Aggarwal, B Christiansen, B Christiansen, BC Lokman, BC Lokman, BM Chassy, C Delorme, C Hill, C Schouler, CA Alpert, CA Shearman, CJ Hueck, CO Pabo, CT Verrips, D Botstein, D Lillehaug, D Lillehaug, D Sinderen, DJ O’Sullivan, DJ O’Sullivan, DO Gostick, DO Gostick, E Küster, E Maguin, E Stanley, EJ Luesink, EJ Luesink, EJ Luesink, F Desiere, F Desiere, G Buist, G Buist, G Ramsay, G Vriend, GM Djordjevic, GM Djordjevic, H Brüssow, H Holo, H Neve, I Biswas, J Bardowski, J Bernhardt, J Green, J Law, J Payne, J Stülke, JB Luchansky, JD Boyce, JW Sanders, JW Sanders, JW Sanders, K Chung, K Leenhouts, K Leenhouts, K Leenhouts, K Schnetz, KI Kodaira, KJ Leenhouts, L Dupont, L Dupont, LJ Beamer, LR Garcia, M Curie, M de Guchte, M de Guchte, M Lieb, M Ptashne, MG Johnsen, MJ Gasson, MJ Weickert, MM Sheehan, MW Lubbers, MW Lubbers, N Goupil-Feuillerat, OP Kuipers, P Hals, PG Ruyter, PGGA Ruyter, PL Madsen, PS Chandry, R Parreira, R Schmid, R Young, R Young, RR Raya, S Challou, S Lucchini, S Lucchini, S Simonen, S Spiro, S Spiro, SA Walker, SB Mclvilc, SG Kim, SM Heller, SM Madsen, SR Swindell, T Sasaki, TM Ramseier, V Vagner, WM Vos, WM Vos, WM Vos, Y Fujita   +110 more
core   +3 more sources

Stochastic Gain and Loss of Novel Transcribed Open Reading Frames in the Human Lineage

Genome Biology and Evolution, 2020
In addition to known genes, much of the human genome is transcribed into RNA. Chance formation of novel open reading frames (ORFs) can lead to the translation of myriad new proteins.
Daniel Dowling, Jonathan F. Schmitz, E. Bornberg-Bauer   +2 more
semanticscholar   +1 more source

The Translation of Non-Canonical Open Reading Frames Controls Mucosal Immunity

Nature, 2018
The annotation of the mammalian protein-coding genome is incomplete. Arbitrary size restriction of open reading frames (ORFs) and the absolute requirement for a methionine codon as the sole initiator of translation have constrained the identification of ...
Ruaidhri Jackson, Lina Kroehling, Alexandra Khitun, Will Bailis, Abigail Jarret, A. York, Omair M. Khan, J. R. Brewer, Mathias H. Skadow, C. Duizer, Christian C. D. Harman, Lelina Chang, Piotr Bielecki, Angel G Solis, H. Steach, Sarah A. Slavoff, Sarah A. Slavoff, R. Flavell, R. Flavell   +18 more
semanticscholar   +1 more source

Conserved elements within open reading frames of mammalian Hox genes

Journal of Biology, 2009
A recent study in BMC Evolutionary Biology shows that many of the open reading frames in mammalian Hox genes are more conserved than expected on the basis of their protein sequence.
Woltering Joost M, Duboule Denis
doaj   +1 more source

Finding errors in DNA sequences [PDF]

, 1992
An algorithm is described that can detect certain errors within coding regions of DNA sequences. The algorithm is based on the idea that an insertion or deletion error within a coding sequence would interrupt the reading frame and cause the correct ...
Posfai, J., Roberts, R. J.
core   +1 more source

uORF-Tools-Workflow for the determination of translation-regulatory upstream open reading frames.

PLoS ONE, 2019
Ribosome profiling (ribo-seq) provides a means to analyze active translation by determining ribosome occupancy in a transcriptome-wide manner. The vast majority of ribosome protected fragments (RPFs) resides within the protein-coding sequence of mRNAs ...
Anica Scholz, Florian Eggenhofer, Rick Gelhausen, Björn Grüning, Kathi Zarnack, Bernhard Brüne, Rolf Backofen, Tobias Schmid   +7 more
doaj   +1 more source

Translation inhibitors cause abnormalities in ribosome profiling experiments [PDF]

, 2014
Ribosome profiling and high-throughput sequencing provide unprecedented opportunities for the analysis of mRNA translation. Using this novel method, several studies have demonstrated the widespread role of short upstream reading frames in translational ...
Gerashchenko, Maxim V., Gladyshev, Vadim N.   +1 more
core   +1 more source

Evidence of a Set of Core-Function Genes in 16 Bacillus Podoviral Genomes with Considerable Genomic Diversity

Viruses, 2023
Bacteriophage genomes represent an enormous level of genetic diversity and provide considerable potential to acquire new insights about viral genome evolution. In this study, the genome sequences of sixteen Bacillus-infecting bacteriophages were explored
Ahmed Ismail, Tanuj Saini, Ahmed Al Qaffas, Ivan Erill, Steven M. Caruso, Louise Temple, Allison A. Johnson   +6 more
doaj   +1 more source

Genome sequence of jumbo phage vB_AbaM_ME3 of Acinetobacter baumanni [PDF]

, 2016
Bacteriophage (phage) vB_AbaM_ME3 was previously isolated from wastewater effluent using the propagating host Acinetobacter baumannii DSM 30007. The full genome was sequenced, revealing it to be the largest Acinetobacter bacteriophage sequenced to date ...
Buttimer, Colin, Coffey, Aidan, Elbreki, Mohamed, Hill, Colin, McAuliffe, Olivia, Neve, Horst, O'Mahony, Jim, O'Sullivan, Lisa, Ross, R. Paul   +8 more
core   +2 more sources

RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs

Genome Biology, 2018
RNA secondary structures in the 5′-untranslated regions (5′-UTR) of mRNAs are key to the post-transcriptional regulation of gene expression. While it is evident that non-canonical Hoogsteen-paired G-quadruplex (rG4) structures somehow contribute to the ...
Pierre Murat, Giovanni Marsico, B. Herdy, A. Ghanbarian, G. Portella, S. Balasubramanian   +5 more
semanticscholar   +1 more source